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    Snrpd1 small nuclear ribonucleoprotein D1 [ Mus musculus (house mouse) ]

    Gene ID: 20641, updated on 27-Nov-2024

    Summary

    Official Symbol
    Snrpd1provided by MGI
    Official Full Name
    small nuclear ribonucleoprotein D1provided by MGI
    Primary source
    MGI:MGI:98344
    See related
    Ensembl:ENSMUSG00000002477 AllianceGenome:MGI:98344
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SMD1
    Summary
    Predicted to enable RNA binding activity and U1 snRNP binding activity. Predicted to be involved in spliceosomal snRNP assembly. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in connective tissue disease; nephritis; proteinuria; and systemic lupus erythematosus. Orthologous to human SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in liver E14 (RPKM 92.1), CNS E11.5 (RPKM 90.4) and 14 other tissues See more
    Orthologs
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    Genomic context

    See Snrpd1 in Genome Data Viewer
    Location:
    18 A1; 18 5.25 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (10617796..10628230)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (10617796..10628230)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene growth regulation by estrogen in breast cancer-like Neighboring gene nuclear transport factor 2, pseudogene 2 Neighboring gene STARR-seq mESC enhancer starr_43798 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:10532920-10533103 Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 1 Neighboring gene abhydrolase domain containing 3 Neighboring gene RIKEN cDNA 4930563E18 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables U1 snRNP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables U1 snRNP binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in spliceosomal snRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spliceosomal snRNP assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spliceosomal snRNP assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of SMN-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SMN-Sm protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of SMN-Sm protein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U1 snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U1 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U12-type spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of U12-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type catalytic step 2 spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type precatalytic spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U2-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U4 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U4 snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U4 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U4/U6 x U5 tri-snRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U4/U6 x U5 tri-snRNP complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of commitment complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of methylosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of methylosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of pICln-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of pICln-Sm protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of pICln-Sm protein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    small nuclear ribonucleoprotein Sm D1
    Names
    sm-D autoantigen
    sm-D1
    snRNP core protein D1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009226.4NP_033252.1  small nuclear ribonucleoprotein Sm D1

      See identical proteins and their annotated locations for NP_033252.1

      Status: PROVISIONAL

      Source sequence(s)
      AC105947
      Consensus CDS
      CCDS29056.1
      UniProtKB/Swiss-Prot
      P62315, Q3UYM0
      Related
      ENSMUSP00000002551.4, ENSMUST00000002551.5
      Conserved Domains (1) summary
      cd01724
      Location:293
      Sm_D1; Sm protein D1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      10617796..10628230
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)