U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    plcd4.L phospholipase C delta 4 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 735225, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    plcd4.L
    Official Full Name
    phospholipase C delta 4 L homeolog
    Primary source
    Xenbase:XB-GENE-965139
    Locus tag
    XELAEV_18044519mg
    See related
    EnsemblRapid:ENSXLAG00005028156 AllianceGenome:Xenbase:XB-GENE-965139
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    plcd4
    Summary
    Predicted to enable calcium ion binding activity and phosphatidylinositol phospholipase C activity. Predicted to act upstream of or within intracellular signal transduction and lipid catabolic process. Predicted to be located in endoplasmic reticulum; membrane; and nucleus. Orthologous to human PLCD4 (phospholipase C delta 4). [provided by Alliance of Genome Resources, Jan 2025]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See plcd4.L in Genome Data Viewer
    Location:
    chromosome: 9_10L
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (63299011..63326689, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (52771421..52785518, complement)

    Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121398284 Neighboring gene uncharacterized LOC121398283 Neighboring gene cytochrome P450, family 27, subfamily A, polypeptide 1 Neighboring gene BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone L homeolog Neighboring gene zinc finger protein 142 L homeolog Neighboring gene CCR4-NOT transcription complex subunit 9L homeolog Neighboring gene ubiquitin specific peptidase 37 L homeolog

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC131193

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
    Names
    PLC-delta-4
    phosphoinositide phospholipase C delta-4
    phospholipase C-delta-4
    NP_001090146.1
    XP_041431701.1
    XP_041431702.1
    XP_041431703.1
    XP_041431704.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001096677.1 → NP_001090146.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

      Status: PROVISIONAL

      Source sequence(s)
      BC108618
      UniProtKB/Swiss-Prot
      Q32NH8
      UniProtKB/TrEMBL
      A0A1L8EVR6, A0A974H3F7
      Related
      ENSXLAP00005083881.1, ENSXLAT00005085519.1
      Conserved Domains (4) summary
      cd00275
      Location:621 → 749
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08631
      Location:289 → 589
      PI-PLCc_delta4; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta4
      cd13363
      Location:18 → 133
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16219
      Location:138 → 277
      EFh_PI-PLCdelta4; EF-hand motif found in phosphoinositide phospholipase C delta 4 (PI-PLC-delta4)

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      63299011..63326689 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041575769.1 → XP_041431703.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1

      UniProtKB/Swiss-Prot
      Q32NH8
      UniProtKB/TrEMBL
      A0A1L8EVR6, A0A974H3F7
      Conserved Domains (4) summary
      cd00275
      Location:621 → 749
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08631
      Location:289 → 589
      PI-PLCc_delta4; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta4
      cd13363
      Location:18 → 133
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16219
      Location:138 → 277
      EFh_PI-PLCdelta4; EF-hand motif found in phosphoinositide phospholipase C delta 4 (PI-PLC-delta4)

    2. XM_041575768.1 → XP_041431702.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1

      UniProtKB/Swiss-Prot
      Q32NH8
      UniProtKB/TrEMBL
      A0A1L8EVR6, A0A974H3F7
      Conserved Domains (4) summary
      cd00275
      Location:621 → 749
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08631
      Location:289 → 589
      PI-PLCc_delta4; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta4
      cd13363
      Location:18 → 133
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16219
      Location:138 → 277
      EFh_PI-PLCdelta4; EF-hand motif found in phosphoinositide phospholipase C delta 4 (PI-PLC-delta4)

    3. XM_041575767.1 → XP_041431701.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1

      UniProtKB/Swiss-Prot
      Q32NH8
      UniProtKB/TrEMBL
      A0A1L8EVR6, A0A974H3F7
      Conserved Domains (4) summary
      cd00275
      Location:621 → 749
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08631
      Location:289 → 589
      PI-PLCc_delta4; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta4
      cd13363
      Location:18 → 133
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16219
      Location:138 → 277
      EFh_PI-PLCdelta4; EF-hand motif found in phosphoinositide phospholipase C delta 4 (PI-PLC-delta4)

    4. XM_041575770.1 → XP_041431704.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1

      UniProtKB/Swiss-Prot
      Q32NH8
      UniProtKB/TrEMBL
      A0A1L8EVR6, A0A974H3F7
      Conserved Domains (4) summary
      cd00275
      Location:621 → 749
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08631
      Location:289 → 589
      PI-PLCc_delta4; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta4
      cd13363
      Location:18 → 133
      PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
      cd16219
      Location:138 → 277
      EFh_PI-PLCdelta4; EF-hand motif found in phosphoinositide phospholipase C delta 4 (PI-PLC-delta4)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32NH8.1 GenPept UniProtKB/Swiss-Prot:Q32NH8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials