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    Snapc2 small nuclear RNA activating complex, polypeptide 2 [ Mus musculus (house mouse) ]

    Gene ID: 102209, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snapc2provided by MGI
    Official Full Name
    small nuclear RNA activating complex, polypeptide 2provided by MGI
    Primary source
    MGI:MGI:1914861
    See related
    Ensembl:ENSMUSG00000011837 AllianceGenome:MGI:1914861
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610007H10Rik
    Summary
    Predicted to enable RNA polymerase II general transcription initiation factor activity. Predicted to be involved in snRNA transcription and transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nuclear body. Is expressed in several structures, including 1st branchial arch; egg cylinder; genitourinary system; limb; and sensory organ. Orthologous to human SNAPC2 (small nuclear RNA activating complex polypeptide 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 32.8), adrenal adult (RPKM 22.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Snapc2 in Genome Data Viewer
    Location:
    8 A1.1; 8 1.99 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (4303102..4306220)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (4253102..4256220)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase 7 Neighboring gene transforming growth factor, beta receptor III-like Neighboring gene cortexin 1 Neighboring gene translocase of inner mitochondrial membrane 44 Neighboring gene STARR-positive B cell enhancer ABC_E4988

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA polymerase II general transcription initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in snRNA transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear body IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    snRNA-activating protein complex subunit 2
    Names
    SNAPc 45 kDa subunit
    SNAPc subunit 2
    snRNA-activating protein complex 45 kDa subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133968.1 → NP_598729.1  snRNA-activating protein complex subunit 2

      See identical proteins and their annotated locations for NP_598729.1

      Status: PROVISIONAL

      Source sequence(s)
      BC011147
      Consensus CDS
      CCDS22081.1
      UniProtKB/Swiss-Prot
      Q3UK17, Q8CBS9, Q91XA5
      Related
      ENSMUSP00000011981.4, ENSMUST00000011981.5
      Conserved Domains (1) summary
      pfam11035
      Location:1 → 355
      SnAPC_2_like; Small nuclear RNA activating complex subunit 2, SNAP190 Myb

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      4303102..4306220
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508683.5 → XP_006508746.1  snRNA-activating protein complex subunit 2 isoform X1

      Conserved Domains (1) summary
      pfam11035
      Location:6 → 276
      SnAPC_2_like; Small nuclear RNA activating complex subunit 2, SNAP190 Myb
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q91XA5.1 GenPept UniProtKB/Swiss-Prot:Q91XA5

    Gene LinkOut

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