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    slc6a9.L solute carrier family 6 member 9 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 108714278, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc6a9.L
    Official Full Name
    solute carrier family 6 member 9 L homeolog
    Primary source
    Xenbase:XB-GENE-17338334
    Locus tag
    XELAEV_18023105mg
    See related
    EnsemblRapid:ENSXLAG00005026097 AllianceGenome:Xenbase:XB-GENE-17338334
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    GlyT1; glyT-1; glyt1b; slc6a9; xGlyT1
    Summary
    Predicted to enable glycine:sodium symporter activity. Predicted to act upstream of or within regulation of glycinergic synaptic transmission. Predicted to be located in plasma membrane. Is expressed in visual system. Orthologous to human SLC6A9 (solute carrier family 6 member 9). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See slc6a9.L in Genome Data Viewer
    Location:
    chromosome: 4L
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (86884565..86976695)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (81591332..81683452)

    Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene Kruppel-like factor 17 L homeolog Neighboring gene uncharacterized LOC108714277 Neighboring gene coiled-coil domain containing 24 L homeolog Neighboring gene von Willebrand factor C domain-containing protein 2-like, gene 2 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression patterns of glycine transporters (xGlyT1, xGlyT2, and xVIAAT) in Xenopus laevis during early development. Wester MR, et al. Gene Expr Patterns, 2008 Apr. PMID 18262473
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The spatial and temporal expression patterns of xGlyT1 during early developmental stages of Xenopus laevis.
      Title: Expression patterns of glycine transporters (xGlyT1, xGlyT2, and xVIAAT) in Xenopus laevis during early development.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables amino acid:sodium symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycine:sodium symporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within neurotransmitter transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of synaptic transmission, glycinergic ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    sodium- and chloride-dependent glycine transporter 1
    Names
    glycine transporter 1
    solute carrier family 6 (neurotransmitter transporter, glycine), member 9 L homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110758.1 → NP_001104228.1  sodium- and chloride-dependent glycine transporter 1

      See identical proteins and their annotated locations for NP_001104228.1

      Status: PROVISIONAL

      Source sequence(s)
      EU117185
      UniProtKB/Swiss-Prot
      A7Y2W8
      Conserved Domains (1) summary
      cd11498
      Location:6 → 590
      SLC6sbd_GlyT1; Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      86884565..86976695
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018258359.2 → XP_018113848.1  sodium- and chloride-dependent glycine transporter 1 isoform X1

      UniProtKB/TrEMBL
      A0A1L8GM87, A0A974D6G5
      Related
      ENSXLAP00005077888.1, ENSXLAT00005079479.1
      Conserved Domains (1) summary
      cd11498
      Location:11 → 595
      SLC6sbd_GlyT1; Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain

    2. XM_041590440.1 → XP_041446374.1  sodium- and chloride-dependent glycine transporter 1 isoform X1

      UniProtKB/TrEMBL
      A0A1L8GM87, A0A974D6G5
      Conserved Domains (1) summary
      cd11498
      Location:11 → 595
      SLC6sbd_GlyT1; Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain

    3. XM_041590439.1 → XP_041446373.1  sodium- and chloride-dependent glycine transporter 1 isoform X1

      UniProtKB/TrEMBL
      A0A1L8GM87, A0A974D6G5
      Conserved Domains (1) summary
      cd11498
      Location:11 → 595
      SLC6sbd_GlyT1; Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain

    4. XM_018258361.2 → XP_018113850.1  sodium- and chloride-dependent glycine transporter 1 isoform X2

      UniProtKB/TrEMBL
      B7ZSD9
      Related
      ENSXLAP00005077791.1, ENSXLAT00005079382.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A7Y2W8.1 GenPept UniProtKB/Swiss-Prot:A7Y2W8

    Gene LinkOut

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