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    Psme3ip1 proteasome activator subunit 3 interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 102122, updated on 9-Dec-2024

    Summary

    Official Symbol
    Psme3ip1provided by MGI
    Official Full Name
    proteasome activator subunit 3 interacting protein 1provided by MGI
    Primary source
    MGI:MGI:1919637
    See related
    Ensembl:ENSMUSG00000031774 AllianceGenome:MGI:1919637
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nip30; Fam192a; 1700001O11Rik; 2310065K24Rik
    Summary
    Predicted to be involved in negative regulation of proteasomal protein catabolic process. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; nasal cavity epithelium; submandibular gland primordium; thymus primordium; and tooth. Orthologous to human PSME3IP1 (proteasome activator subunit 3 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 21.0), CNS E14 (RPKM 19.9) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Psme3ip1 in Genome Data Viewer
    Location:
    8 C5; 8 46.58 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (95301568..95328483, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (94574940..94601962, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene NLR family, CARD domain containing 5 Neighboring gene STARR-seq mESC enhancer starr_22357 Neighboring gene predicted gene, 51584 Neighboring gene microRNA 7072 Neighboring gene copine II Neighboring gene STARR-seq mESC enhancer starr_22358 Neighboring gene predicted gene, 38555 Neighboring gene STARR-seq mESC enhancer starr_22359 Neighboring gene STARR-positive B cell enhancer mm9_chr8:97125541-97125842 Neighboring gene predicted gene, 57522 Neighboring gene ring finger and SPRY domain containing 1 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E8257 Neighboring gene ADP-ribosylation factor-like 2 binding protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of proteasomal protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of proteasomal protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of protein binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    PSME3-interacting protein
    Names
    NEFA-interacting nuclear protein NIP30
    PA28G-interacting protein
    family with sequence similarity 192, member A
    protein FAM192A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363456.1NP_001350385.1  PSME3-interacting protein isoform a

      Status: VALIDATED

      Source sequence(s)
      AC102358
      Consensus CDS
      CCDS40439.1
      UniProtKB/Swiss-Prot
      Q3U9X3, Q8R0C9, Q91WE2
      Conserved Domains (1) summary
      pfam10187
      Location:1598
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    2. NM_001363457.1NP_001350386.1  PSME3-interacting protein isoform b

      Status: VALIDATED

      Source sequence(s)
      AC102358
      UniProtKB/TrEMBL
      A0A1D5RLU2
      Related
      ENSMUSP00000148506.2, ENSMUST00000212791.2
      Conserved Domains (1) summary
      pfam10187
      Location:1598
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    3. NM_028221.4NP_082497.2  PSME3-interacting protein isoform a

      See identical proteins and their annotated locations for NP_082497.2

      Status: VALIDATED

      Source sequence(s)
      AK050704, BC016088, BY245102
      Consensus CDS
      CCDS40439.1
      UniProtKB/Swiss-Prot
      Q3U9X3, Q8R0C9, Q91WE2
      Related
      ENSMUSP00000034226.7, ENSMUST00000034226.8
      Conserved Domains (1) summary
      pfam10187
      Location:1598
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30

    RNA

    1. NR_156692.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC102358

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      95301568..95328483 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530540.4XP_006530603.1  PSME3-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006530603.1

      UniProtKB/Swiss-Prot
      Q3U9X3, Q8R0C9, Q91WE2
      Conserved Domains (1) summary
      pfam10187
      Location:1598
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    2. XM_006530541.4XP_006530604.1  PSME3-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006530604.1

      UniProtKB/Swiss-Prot
      Q3U9X3, Q8R0C9, Q91WE2
      Conserved Domains (1) summary
      pfam10187
      Location:1598
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    3. XM_011248256.4XP_011246558.1  PSME3-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_011246558.1

      UniProtKB/Swiss-Prot
      Q3U9X3, Q8R0C9, Q91WE2
      Conserved Domains (1) summary
      pfam10187
      Location:1598
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    4. XM_036153704.1XP_036009597.1  PSME3-interacting protein isoform X1

      UniProtKB/Swiss-Prot
      Q3U9X3, Q8R0C9, Q91WE2
      Conserved Domains (1) summary
      pfam10187
      Location:1598
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    5. XM_036153703.1XP_036009596.1  PSME3-interacting protein isoform X1

      UniProtKB/Swiss-Prot
      Q3U9X3, Q8R0C9, Q91WE2
      Conserved Domains (1) summary
      pfam10187
      Location:1598
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30
    6. XM_006530542.4XP_006530605.1  PSME3-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006530605.1

      UniProtKB/Swiss-Prot
      Q3U9X3, Q8R0C9, Q91WE2
      Conserved Domains (1) summary
      pfam10187
      Location:1598
      Nefa_Nip30_N; N-terminal domain of NEFA-interacting nuclear protein NIP30