nup188 nucleoporin 188kDa [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: nup188provided by Xenbase
Official Full Name: nucleoporin 188kDaprovided by Xenbase
Primary source: Xenbase:XB-GENE-5933085
See related: Ensembl:ENSXETG00000012903 AllianceGenome:Xenbase:XB-GENE-5933085
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to be a structural constituent of nuclear pore. Acts upstream of or within cilium assembly. Predicted to be located in nucleus. Predicted to be part of nuclear pore inner ring. Is expressed in anatomical system; pharyngeal arch; and primary germ layer. Human ortholog(s) of this gene implicated in Sandestig-Stefanova syndrome and respiratory failure. Orthologous to human NUP188 (nucleoporin 188). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 8

Exon count:: 44

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	8	NC_030684.2 (22836127..22854354, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	8	NC_030684.1 (4058527..4076730)

Chromosome 8 - NC_030684.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables structural constituent of nuclear pore	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of nuclear pore	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA export from nucleus	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cilium assembly	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within mRNA transport	IEA Inferred from Electronic Annotation more info
involved_in protein import into nucleus	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of nuclear pore	IEA Inferred from Electronic Annotation more info
part_of nuclear pore inner ring	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: nucleoporin NUP188; nucleoporin NUP188 homolog

Names: Nucleoporin NUP188 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001113820.1 → NP_001107292.1 nucleoporin NUP188

See identical proteins and their annotated locations for NP_001107292.1

Status: PROVISIONAL

Source sequence(s)

BC155686

UniProtKB/Swiss-Prot

A9JRJ6, F6WXT2

UniProtKB/TrEMBL

A0A5S6M1K6

Related

ENSXETP00000028229.3, ENSXETT00000028229.4

Conserved Domains (1) summary

pfam10487
Location:30 → 935

Nup188; Nucleoporin subcomplex protein binding to Pom34

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

22836127..22854354 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_012967947.3 → XP_012823401.1 nucleoporin NUP188 homolog isoform X1

UniProtKB/Swiss-Prot

A9JRJ6, F6WXT2

UniProtKB/TrEMBL

A0A8J0SS94

Conserved Domains (1) summary

pfam10487
Location:30 → 935

Nup188; Nucleoporin subcomplex protein binding to Pom34