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    Celf1 CUGBP, Elav-like family member 1 [ Mus musculus (house mouse) ]

    Gene ID: 13046, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Celf1provided by MGI
    Official Full Name
    CUGBP, Elav-like family member 1provided by MGI
    Primary source
    MGI:MGI:1342295
    See related
    Ensembl:ENSMUSG00000005506 AllianceGenome:MGI:1342295
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CUGBP; NAB50; CUG-BP; Cugbp1; HNAB50; Brunol2; CUG-BP1; D2Wsu101e; 1600010O03Rik
    Summary
    Enables lncRNA binding activity; mRNA binding activity; and translation initiation factor binding activity. Acts upstream of or within several processes, including mRNA splice site recognition; regulation of alternative mRNA splicing, via spliceosome; and spermatid development. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including branchial arch; central nervous system; early embryo; musculature; and testis. Orthologous to human CELF1 (CUGBP Elav-like family member 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 28.2), whole brain E14.5 (RPKM 28.2) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Celf1 in Genome Data Viewer
    Location:
    2 E1; 2 50.44 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (90770604..90849842)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (90940259..91019497)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene kelch repeat and BTB (POZ) domain containing 4 Neighboring gene protein tyrosine phosphatase, mitochondrial 1 Neighboring gene STARR-seq mESC enhancer starr_05099 Neighboring gene STARR-seq mESC enhancer starr_05101 Neighboring gene STARR-positive B cell enhancer mm9_chr2:90854051-90854352 Neighboring gene STARR-positive B cell enhancer ABC_E5944 Neighboring gene receptor-associated protein of the synapse Neighboring gene STARR-positive B cell enhancer ABC_E7840 Neighboring gene predicted gene 13778 Neighboring gene proteasome (prosome, macropain) 26S subunit, ATPase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Evaluating the effects of CELF1 deficiency in a mouse model of RNA toxicity. Kim YK, et al. Hum Mol Genet, 2014 Jan 15. PMID 24001600, Free PMC Article
    2. Inactivation of the Celf1 gene that encodes an RNA-binding protein delays the first wave of spermatogenesis in mice. Cibois M, et al. PLoS One, 2012. PMID 23056285, Free PMC Article
    3. The role of CUGBP1 in age-dependent changes of liver functions. Jones K, et al. Ageing Res Rev, 2012 Sep. PMID 22446383, Free PMC Article
    4. CELF1 contributes to aberrant alternative splicing patterns in the type 1 diabetic heart. Belanger K, et al. Biochem Biophys Res Commun, 2018 Sep 18. PMID 30158053, Free PMC Article
    5. Correction of GSK3β at young age prevents muscle pathology in mice with myotonic dystrophy type 1. Wei C, et al. FASEB J, 2018 Apr. PMID 29203592, Free PMC Article

    See all (96) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology.
      Title: High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology.
    2. Long noncoding RNA uc.230/CUG-binding protein 1 axis sustains intestinal epithelial homeostasis and response to tissue injury.
      Title: Long noncoding RNA uc.230/CUG-binding protein 1 axis sustains intestinal epithelial homeostasis and response to tissue injury.
    3. Increased nuclear but not cytoplasmic activities of CELF1 protein leads to muscle wasting.
      Title: Increased nuclear but not cytoplasmic activities of CELF1 protein leads to muscle wasting.
    4. CELF1 promotes vascular endothelial growth factor degradation resulting in impaired microvasculature in heart failure.
      Title: CELF1 promotes vascular endothelial growth factor degradation resulting in impaired microvasculature in heart failure.
    5. The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development.
      Title: The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development.
    6. RNA-seq analysis of mouse neocortical polysomes demonstrated that the translation of distinct mRNA isoforms of the RNA binding protein (RBP), Elavl4, in radial glia progenitors and early neurons depends on its alternative 5' UTRs. 5' UTR-driven Elavl4 isoform-specific translation depends on upstream control by another RBP, Celf1. Celf1 regulation of Elavl4 translation dictates development of glutamatergic neurons.
      Title: Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development.
    7. miR-206 helped rescue myogenic deficiency by inhibiting CUGBP1 accumulation in cell models of myotonic dystrophy. These data suggest that increased miR-206 levels in myoblasts may lead to better skeletal muscle differentiation.
      Title: Mir-206 partially rescues myogenesis deficiency by inhibiting CUGBP1 accumulation in the cell models of myotonic dystrophy.
    8. These results indicate that CELF1 target RNAs are aberrantly spliced in the Type 1 diabetic heart leading to abnormal gene expression.
      Title: CELF1 contributes to aberrant alternative splicing patterns in the type 1 diabetic heart.
    9. this study shows that the absence of Celf1 causes neonatal cardiac dysfunction and transcriptome changes
      Title: Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1.
    10. Results found that the blood level of CUGBP1 in mice was decreased during the progression of acute myocardial infarction (AMI) and demonstrate that CUGBP1 is functionally important in AMI. This finding reveals the roles of CUGBP1 in the heart not only during development but also in cardiac disease.
      Title: Reconstitution of HuR-Inhibited CUGBP1 Expression Protects Cardiomyocytes from Acute Myocardial Infarction-Induced Injury.
    Submit: New GeneRIF Correction See all GeneRIFs (38)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 
    • Targeted (3)  1 citation

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables BRE binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables BRE binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables lncRNA binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA 3'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables pre-mRNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables translation initiation factor binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cerebral cortex development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA destabilization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in mRNA splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within mRNA splice site recognition IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mRNA splice site recognition ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of negative regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of epithelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within positive regulation of multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in post-transcriptional gene silencing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of RNA splicing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of RNA splicing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of inflammatory response ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytoplasmic stress granule ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in male germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in perinucleolar compartment ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CUGBP Elav-like family member 1
    Names
    50 kDa nuclear polyadenylated RNA-binding protein
    CELF-1
    CUG triplet repeat RNA-binding protein 1
    CUG-BP- and ETR-3-like factor 1
    EDEN-BP homolog
    RNA-binding protein BRUNOL-2
    brain protein F41
    bruno-like protein 2
    deadenylation factor CUG-BP
    deadenylation factor EDEN-BP
    embryo deadenylation element-binding protein homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001244891.2 → NP_001231820.1  CUGBP Elav-like family member 1 isoform 2

      See identical proteins and their annotated locations for NP_001231820.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has an alternate exon in the 5' region, which results in a downstream AUG start codon, and has an additional segment in the 3' UTR, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1.
      Source sequence(s)
      AL672241
      Consensus CDS
      CCDS16421.1
      UniProtKB/Swiss-Prot
      A2AFW9, A2AFX0, A2AFX1, A2AFX2, P28659, Q3U0N2, Q3UP93, Q3UY22, Q8R532, Q99PE1, Q9CXE5, Q9EPJ8, Q9JI37
      Related
      ENSMUSP00000136109.2, ENSMUST00000177642.8
      Conserved Domains (3) summary
      cd12638
      Location:394 → 485
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:15 → 98
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107 → 187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    2. NM_001244903.2 → NP_001231832.1  CUGBP Elav-like family member 1 isoform 2

      See identical proteins and their annotated locations for NP_001231832.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an exon in the 5' region, which results in a downstream AUG start codon, and has an additional segment in the 3' UTR, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1.
      Source sequence(s)
      AL672241
      Consensus CDS
      CCDS16421.1
      UniProtKB/Swiss-Prot
      A2AFW9, A2AFX0, A2AFX1, A2AFX2, P28659, Q3U0N2, Q3UP93, Q3UY22, Q8R532, Q99PE1, Q9CXE5, Q9EPJ8, Q9JI37
      Related
      ENSMUSP00000070438.8, ENSMUST00000068747.14
      Conserved Domains (3) summary
      cd12638
      Location:394 → 485
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:15 → 98
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107 → 187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    3. NM_001406164.1 → NP_001393093.1  CUGBP Elav-like family member 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL672241
      Related
      ENSMUSP00000107082.3, ENSMUST00000111455.9

    4. NM_001406165.1 → NP_001393094.1  CUGBP Elav-like family member 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL672241

    5. NM_001406166.1 → NP_001393095.1  CUGBP Elav-like family member 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL672241
      UniProtKB/Swiss-Prot
      A2AFW9, A2AFX0, A2AFX1, A2AFX2, P28659, Q3U0N2, Q3UP93, Q3UY22, Q8R532, Q99PE1, Q9CXE5, Q9EPJ8, Q9JI37

    6. NM_001406167.1 → NP_001393096.1  CUGBP Elav-like family member 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL672241
      UniProtKB/Swiss-Prot
      A2AFW9, A2AFX0, A2AFX1, A2AFX2, P28659, Q3U0N2, Q3UP93, Q3UY22, Q8R532, Q99PE1, Q9CXE5, Q9EPJ8, Q9JI37
      Related
      ENSMUSP00000107076.2, ENSMUST00000111449.8

    7. NM_001406168.1 → NP_001393097.1  CUGBP Elav-like family member 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL672241

    8. NM_001406169.1 → NP_001393098.1  CUGBP Elav-like family member 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL672241

    9. NM_001406170.1 → NP_001393099.1  CUGBP Elav-like family member 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL672241

    10. NM_001406171.1 → NP_001393100.1  CUGBP Elav-like family member 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL672241

    11. NM_001406172.1 → NP_001393101.1  CUGBP Elav-like family member 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL672241
      UniProtKB/TrEMBL
      A0A0R4J0T5

    12. NM_001406173.1 → NP_001393102.1  CUGBP Elav-like family member 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL672241
      UniProtKB/TrEMBL
      A0A0R4J0T5

    13. NM_001406174.1 → NP_001393103.1  CUGBP Elav-like family member 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL672241
      UniProtKB/TrEMBL
      A0A0R4J0T5
      Related
      ENSMUSP00000064323.7, ENSMUST00000068726.13

    14. NM_001406175.1 → NP_001393104.1  CUGBP Elav-like family member 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL672241
      UniProtKB/TrEMBL
      A0A0R4J0T5

    15. NM_001406176.1 → NP_001393105.1  CUGBP Elav-like family member 1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL672241

    16. NM_001406177.1 → NP_001393106.1  CUGBP Elav-like family member 1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL672241

    17. NM_001406178.1 → NP_001393107.1  CUGBP Elav-like family member 1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL672241

    18. NM_001406179.1 → NP_001393108.1  CUGBP Elav-like family member 1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL672241

    19. NM_001406180.1 → NP_001393109.1  CUGBP Elav-like family member 1 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AL672241

    20. NM_001406181.1 → NP_001393110.1  CUGBP Elav-like family member 1 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AL672241

    21. NM_001406182.1 → NP_001393111.1  CUGBP Elav-like family member 1 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AL672241

    22. NM_001406183.1 → NP_001393112.1  CUGBP Elav-like family member 1 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AL672241

    23. NM_001406184.1 → NP_001393113.1  CUGBP Elav-like family member 1 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AL672241

    24. NM_017368.4 → NP_059064.2  CUGBP Elav-like family member 1 isoform 1

      See identical proteins and their annotated locations for NP_059064.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AL672241
      Consensus CDS
      CCDS16420.1
      UniProtKB/Swiss-Prot
      P28659
      Related
      ENSMUSP00000005643.8, ENSMUST00000005643.14
      Conserved Domains (3) summary
      cd12638
      Location:421 → 512
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:42 → 125
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:134 → 214
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    25. NM_198683.3 → NP_941955.1  CUGBP Elav-like family member 1 isoform 2

      See identical proteins and their annotated locations for NP_941955.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon in the 5' region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1.
      Source sequence(s)
      AL672241
      Consensus CDS
      CCDS16421.1
      UniProtKB/Swiss-Prot
      A2AFW9, A2AFX0, A2AFX1, A2AFX2, P28659, Q3U0N2, Q3UP93, Q3UY22, Q8R532, Q99PE1, Q9CXE5, Q9EPJ8, Q9JI37
      Related
      ENSMUSP00000107078.4, ENSMUST00000111451.10
      Conserved Domains (3) summary
      cd12638
      Location:394 → 485
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:15 → 98
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107 → 187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      90770604..90849842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036158049.1 → XP_036013942.1  CUGBP Elav-like family member 1 isoform X13

      Conserved Domains (3) summary
      cd12638
      Location:334 → 423
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:15 → 98
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107 → 187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    2. XM_030247110.1 → XP_030102970.1  CUGBP Elav-like family member 1 isoform X7

      Related
      ENSMUSP00000107075.2, ENSMUST00000111448.2
      Conserved Domains (3) summary
      cd12631
      Location:15 → 98
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107 → 187
      RRM2_CELF1_2; RNA recognition motif 2 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12638
      Location:391 → 482
      RRM3_CELF1_2; RNA recognition motif 3 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    3. XM_030247123.1 → XP_030102983.1  CUGBP Elav-like family member 1 isoform X1

      Conserved Domains (3) summary
      cd12638
      Location:422 → 513
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:42 → 125
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:134 → 214
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    4. XM_030247114.1 → XP_030102974.1  CUGBP Elav-like family member 1 isoform X9

      Conserved Domains (3) summary
      cd12638
      Location:362 → 451
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:42 → 125
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:134 → 214
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    5. XM_036158039.1 → XP_036013932.1  CUGBP Elav-like family member 1 isoform X9

      Conserved Domains (3) summary
      cd12638
      Location:362 → 451
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:42 → 125
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:134 → 214
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    6. XM_030247118.1 → XP_030102978.1  CUGBP Elav-like family member 1 isoform X10

      Conserved Domains (3) summary
      cd12631
      Location:42 → 125
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:134 → 214
      RRM2_CELF1_2; RNA recognition motif 2 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12638
      Location:361 → 450
      RRM3_CELF1_2; RNA recognition motif 3 in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    7. XM_030247086.1 → XP_030102946.1  CUGBP Elav-like family member 1 isoform X3

      Conserved Domains (3) summary
      cd12638
      Location:418 → 509
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:42 → 125
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:134 → 214
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    8. XM_017315295.1 → XP_017170784.1  CUGBP Elav-like family member 1 isoform X1

      Conserved Domains (3) summary
      cd12638
      Location:422 → 513
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:42 → 125
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:134 → 214
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    9. XM_036158048.1 → XP_036013941.1  CUGBP Elav-like family member 1 isoform X12

      Conserved Domains (3) summary
      cd12638
      Location:335 → 424
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:15 → 98
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107 → 187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    10. XM_036158029.1 → XP_036013922.1  CUGBP Elav-like family member 1 isoform X5

      UniProtKB/TrEMBL
      A0A0R4J0T5
      Conserved Domains (3) summary
      cd12638
      Location:395 → 486
      RRM3_CELF1_2; RNA recognition motif 3 (RRM3) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins
      cd12631
      Location:15 → 98
      RRM1_CELF1_2_Bruno; RNA recognition motif 1 (RRM1) found in CUGBP Elav-like family member CELF-1, CELF-2, Drosophila melanogaster Bruno protein and similar proteins
      cd12634
      Location:107 → 187
      RRM2_CELF1_2; RNA recognition motif 2 (RRM2) found in CUGBP Elav-like family member CELF-1, CELF-2 and similar proteins

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_198016.1: Suppressed sequence

      Description
      NM_198016.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P28659.2 GenPept UniProtKB/Swiss-Prot:P28659

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