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    Xlr5c X-linked lymphocyte-regulated 5C [ Mus musculus (house mouse) ]

    Gene ID: 27084, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Xlr5cprovided by MGI
    Official Full Name
    X-linked lymphocyte-regulated 5Cprovided by MGI
    Primary source
    MGI:MGI:1350981
    See related
    Ensembl:ENSMUSG00000067764 AllianceGenome:MGI:1350981
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Xlr5
    Summary
    Predicted to be involved in meiotic cell cycle and spermatid development. Located in chromosome and nucleus. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; hindgut diverticulum; lung; and skin. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward placenta adult (RPKM 12.6) See more
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    Genomic context

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    See Xlr5c in Genome Data Viewer
    Location:
    X A7.3; X 37.29 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (72326967..72337469, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (73283361..73293863, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene X-linked lymphocyte-regulated 4C Neighboring gene X-linked lymphocyte-regulated 3C Neighboring gene STARR-seq mESC enhancer starr_47345 Neighboring gene PWWP domain containing 4, pseudogene Neighboring gene nucleoside diphosphate kinase B pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification and Characterization of Xlr5c as a Novel Nuclear Localization Protein in Mouse Germ Cells. Zhuang XJ, et al. PLoS One, 2015. PMID 26075718, Free PMC Article
    2. A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Levin ML, et al. Genome Res, 1996 Jun. PMID 8828036
    3. Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice. Davies W, et al. Nat Genet, 2005 Jun. PMID 15908950
    4. Identification of a cluster of X-linked imprinted genes in mice. Raefski AS, et al. Nat Genet, 2005 Jun. PMID 15908953
    5. Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. Mallon AM, et al. Genome Res, 2000 Jun. PMID 10854409, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC141130

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spermatid development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in synaptonemal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    X-linked lymphocyte-regulated protein 5C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031493.1 → NP_113681.1  X-linked lymphocyte-regulated protein 5C

      See identical proteins and their annotated locations for NP_113681.1

      Status: PROVISIONAL

      Source sequence(s)
      AL049866
      Consensus CDS
      CCDS30198.1
      UniProtKB/Swiss-Prot
      Q9JJR2
      UniProtKB/TrEMBL
      A2BI49
      Related
      ENSMUSP00000085796.4, ENSMUST00000088450.4
      Conserved Domains (1) summary
      pfam04803
      Location:78 → 177
      Cor1; Cor1/Xlr/Xmr conserved region

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      72326967..72337469 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006528067.3 → XP_006528130.1  X-linked lymphocyte-regulated protein 5C isoform X1

      See identical proteins and their annotated locations for XP_006528130.1

      UniProtKB/TrEMBL
      A2AIE6, Q80UK6
      Conserved Domains (1) summary
      pfam04803
      Location:78 → 207
      Cor1; Cor1/Xlr/Xmr conserved region

    2. XM_030251358.1 → XP_030107218.1  X-linked lymphocyte-regulated protein 5C isoform X2

      UniProtKB/TrEMBL
      Q80UK6
      Conserved Domains (1) summary
      pfam04803
      Location:78 → 174
      Cor1; Cor1/Xlr/Xmr conserved region

    3. XM_006528064.3 → XP_006528127.1  X-linked lymphocyte-regulated protein 5C isoform X1

      See identical proteins and their annotated locations for XP_006528127.1

      UniProtKB/TrEMBL
      A2AIE6, Q80UK6
      Related
      ENSMUSP00000110147.3, ENSMUST00000114503.9
      Conserved Domains (1) summary
      pfam04803
      Location:78 → 207
      Cor1; Cor1/Xlr/Xmr conserved region

    4. XM_006528065.3 → XP_006528128.1  X-linked lymphocyte-regulated protein 5C isoform X1

      See identical proteins and their annotated locations for XP_006528128.1

      UniProtKB/TrEMBL
      A2AIE6, Q80UK6
      Conserved Domains (1) summary
      pfam04803
      Location:78 → 207
      Cor1; Cor1/Xlr/Xmr conserved region

    5. XM_006528066.3 → XP_006528129.1  X-linked lymphocyte-regulated protein 5C isoform X1

      See identical proteins and their annotated locations for XP_006528129.1

      UniProtKB/TrEMBL
      A2AIE6, Q80UK6
      Conserved Domains (1) summary
      pfam04803
      Location:78 → 207
      Cor1; Cor1/Xlr/Xmr conserved region

    6. XM_011247607.2 → XP_011245909.1  X-linked lymphocyte-regulated protein 5C isoform X3

      Conserved Domains (1) summary
      pfam04803
      Location:24 → 153
      Cor1; Cor1/Xlr/Xmr conserved region
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9JJR2.1 GenPept UniProtKB/Swiss-Prot:Q9JJR2

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