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    faxc-2 Failed axon connections homolog [ Caenorhabditis elegans ]

    Gene ID: 190020, updated on 9-Dec-2024

    Summary

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    Official Symbol
    faxc-2
    Official Full Name
    Failed axon connections homolog
    Primary source
    WormBase:WBGene00012987
    Locus tag
    CELE_Y48C3A.3
    See related
    AllianceGenome:WB:WBGene00012987
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in cytoplasm. Orthologous to human FAXC (failed axon connections homolog, metaxin like GST domain containing). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See faxc-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (13309290..13311488)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serine-rich adhesin for platelets;Uncharacterized protein;uncharacterized protein Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein mac-1 Neighboring gene Single-stranded DNA-binding protein homolog sam-10 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SPD-3 is required for spindle alignment in Caenorhabditis elegans embryos and localizes to mitochondria. Dinkelmann MV, et al. Genetics, 2007 Nov. PMID 17947426, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Failed axon connections homolog
    NP_496813.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      13309290..13311488
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064412.2 → NP_496813.1  Failed axon connections homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496813.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NAG5
      Conserved Domains (2) summary
      cd03193
      Location:218 → 287
      GST_C_Metaxin; C-terminal, alpha helical domain of Metaxin and related proteins
      cd03080
      Location:58 → 132
      GST_N_Metaxin_like; GST_N family, Metaxin subfamily, Metaxin-like proteins; a heterogenous group of proteins, predominantly uncharacterized, with similarity to metaxins and GSTs. Metaxin 1 is a component of a preprotein import complex of the mitochondrial outer membrane. It ...
    Nucleotide Protein
    Heading Accession and Version

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