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    phyh-1 phytanoyl-CoA dioxygenase [ Caenorhabditis elegans ]

    Gene ID: 191350, updated on 9-Dec-2024

    Summary

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    Official Symbol
    phyh-1
    Official Full Name
    phytanoyl-CoA dioxygenase
    Primary source
    WormBase:WBGene00013999
    Locus tag
    CELE_ZK550.5
    See related
    AllianceGenome:WB:WBGene00013999
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phytanoyl-CoA dioxygenase activity. Predicted to be involved in fatty acid alpha-oxidation. Is expressed in nerve ring. Human ortholog(s) of this gene implicated in Refsum disease; Zellweger syndrome; orofacial cleft; and peroxisomal disease. Orthologous to human PHYH (phytanoyl-CoA 2-hydroxylase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See phyh-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (17257501..17259410, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene ncRNA Neighboring gene Peptidase M3A/M3B catalytic domain-containing protein Neighboring gene ncRNA Neighboring gene HTH TFE/IIEalpha-type domain-containing protein Neighboring gene ncRNA Neighboring gene putative phytanoyl-CoA dioxygenase Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phytanoyl-CoA dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phytanoyl-CoA dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid alpha-oxidation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fatty acid alpha-oxidation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    phytanoyl-CoA dioxygenase
    NP_503061.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      17257501..17259410 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070660.5 → NP_503061.1  phytanoyl-CoA dioxygenase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503061.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62514
      Conserved Domains (1) summary
      pfam05721
      Location:40 → 260
      PhyH; Phytanoyl-CoA dioxygenase (PhyH)
    Nucleotide Protein
    Heading Accession and Version

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