haf-8 HAlF transporter (PGP related) [Caenorhabditis elegans] - Gene

Summary

Official Symbol: haf-8
Official Full Name: HAlF transporter (PGP related)
Primary source: WormBase:WBGene00001818
Locus tag: CELE_Y57G11C.1
See related: AllianceGenome:WB:WBGene00001818
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); bronchial disease (multiple); cervical cancer (multiple); and systemic scleroderma (multiple). Orthologous to human ABCB9 (ATP binding cassette subfamily B member 9); TAP1 (transporter 1, ATP binding cassette subfamily B member); and TAP2 (transporter 2, ATP binding cassette subfamily B member). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in response to chemical	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

NP_502776.1

Product from WormBase gene class haf;
Partially confirmed by transcript evidence

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The following sections contain reference sequences that belong to a specific genome build. Explain