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    Y46E12A.3 Glutaredoxin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175323, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y46E12A.3
    Official Full Name
    Glutaredoxin domain-containing protein
    Primary source
    WormBase:WBGene00021593
    Locus tag
    CELE_Y46E12A.3
    See related
    AllianceGenome:WB:WBGene00021593
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in sensory perception of sound. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 25. Orthologous to human GRXCR1 (glutaredoxin and cysteine rich domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y46E12A.3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (1752183..1754942, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein Neighboring gene DUF72 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in sensory perception of sound IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Glutaredoxin domain-containing protein
    NP_497453.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1752183..1754942 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065052.1 → NP_497453.1  Glutaredoxin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497453.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3V8
      Conserved Domains (1) summary
      cd03031
      Location:73 → 230
      GRX_GRX_like; Glutaredoxin (GRX) family, GRX-like domain containing protein subfamily; composed of uncharacterized eukaryotic proteins containing a GRX-like domain having only one conserved cysteine, aligning to the C-terminal cysteine of the CXXC motif of GRXs. This ...
    Nucleotide Protein
    Heading Accession and Version

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