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    CG31559 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40749, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31559provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051559
    Locus tag
    Dmel_CG31559
    See related
    AllianceGenome:FB:FBgn0051559
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    31559; CG11461; CG15584; Dmel\CG31559
    Summary
    Predicted to be involved in sensory perception of sound. Is expressed in embryonic dorsal epidermis; embryonic head epidermis; embryonic hypopharynx; embryonic ventral epidermis; and gut section. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 25. Orthologous to human GRXCR1 (glutaredoxin and cysteine rich domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31559 in Genome Data Viewer
    Location:
    83D5-83D5; 3-47.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6150116..6157235, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1975838..1982957, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43486 Neighboring gene long non-coding RNA:CR43487 Neighboring gene uncharacterized protein Neighboring gene Osiris 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Natural Genetic Variation Screen in Drosophila Identifies Wnt Signaling, Mitochondrial Metabolism, and Redox Homeostasis Genes as Modifiers of Apoptosis. Palu RAS, et al. G3 (Bethesda), 2019 Dec 3. PMID 31570502, Free PMC Article
    2. Gbb glutathionylation promotes its proteasome-mediated degradation to inhibit synapse growth. Hossain MS, et al. J Cell Biol, 2023 Sep 4. PMID 37389657, Free PMC Article
    3. dusky-like is required to maintain the integrity and planar cell polarity of hairs during the development of the Drosophila wing. Adler PN, et al. Dev Biol, 2013 Jul 1. PMID 23623898, Free PMC Article
    4. Trichomes on female reproductive tract: rapid diversification and underlying gene regulatory network in Drosophila suzukii and its related species. Tanaka KM, et al. BMC Ecol Evol, 2022 Jul 28. PMID 35902820, Free PMC Article
    5. Early-life nutrition interacts with developmental genes to shape the brain and sleep behavior in Drosophila melanogaster. Olivares GH, et al. Sleep, 2023 Apr 12. PMID 36718043

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in sensory perception of sound IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31559-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6150116..6157235 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169127.3 → NP_731045.1  uncharacterized protein Dmel_CG31559 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731045.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SZ66, Q9VNL4
      Related
      FBpp0078265
      Conserved Domains (1) summary
      cd03031
      Location:306 → 451
      GRX_GRX_like; Glutaredoxin (GRX) family, GRX-like domain containing protein subfamily; composed of uncharacterized eukaryotic proteins containing a GRX-like domain having only one conserved cysteine, aligning to the C-terminal cysteine of the CXXC motif of GRXs. This ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VNL4.2 Q9VNL4

    Gene LinkOut

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