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    Ly6a2 lymphocyte antigen 6 family member A2 [ Mus musculus (house mouse) ]

    Gene ID: 546643, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ly6a2provided by MGI
    Official Full Name
    lymphocyte antigen 6 family member A2provided by MGI
    Primary source
    MGI:MGI:3612406
    See related
    Ensembl:ENSMUSG00000121499 AllianceGenome:MGI:3612406
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    I830127L07Rik
    Expression
    Biased expression in liver E18 (RPKM 12.3), spleen adult (RPKM 2.0) and 4 other tissues See more
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    Genomic context

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    See Ly6a2 in Genome Data Viewer
    Location:
    15 D3; 15 34.29 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (75003141..75006977, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (75131292..75135128, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene 5960 Neighboring gene STARR-seq mESC enhancer starr_39009 Neighboring gene STARR-positive B cell enhancer ABC_E11591 Neighboring gene lymphocyte antigen 6 family memberC2 Neighboring gene lymphocyte antigen 6 family member G Neighboring gene predicted gene 28117

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse Ly-6 proteins and their extended family: markers of cell differentiation and regulators of cell signaling. Bamezai A. Arch Immunol Ther Exp (Warsz), 2004 Jul-Aug. PMID 15467490
    2. Organization, evolution and functions of the human and mouse Ly6/uPAR family genes. Loughner CL, et al. Hum Genomics, 2016 Apr 21. PMID 27098205, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    lymphocyte antigen 6 complex, locus A2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001378240.1 → NP_001365169.1  lymphocyte antigen 6 complex, locus A2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC116498
      UniProtKB/TrEMBL
      Q3U8E9
      Related
      ENSMUST00000246956.2
      Conserved Domains (1) summary
      cd00117
      Location:27 → 107
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

    2. NM_001378241.1 → NP_001365170.1  lymphocyte antigen 6 complex, locus A2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC116498
      UniProtKB/TrEMBL
      Q3U8E9
      Related
      ENSMUST00000242842.2
      Conserved Domains (1) summary
      cd00117
      Location:27 → 107
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      75003141..75006977 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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