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    UNC13B unc-13 homolog B [ Trachypithecus francoisi (Francois's langur) ]

    Gene ID: 117099019, updated on 19-Mar-2024

    Summary

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    Gene symbol
    UNC13B
    Gene description
    unc-13 homolog B
    See related
    EnsemblRapid:ENSTFRG00000013039
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Trachypithecus francoisi
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Trachypithecus
    Orthologs
    human mouse all
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    Genomic context

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    See UNC13B in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    100 current Tfra_2.0 (GCF_009764315.1) Unplaced Scaffold NW_022681461.1 (92315217..92488832, complement)

    NW_022681461.1Genomic Context describing neighboring genes Neighboring gene ciliary microtubule inner protein 2B Neighboring gene RUN and SH3 domain containing 2 Neighboring gene phospholipid-transporting ATPase FetA-like Neighboring gene protein FAM205A-like Neighboring gene SPATA31 subfamily F member 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_022681461 Unplaced Scaffold Reference Tfra_2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables diacylglycerol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables syntaxin-1 binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dense core granule priming IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuromuscular junction development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in presynaptic dense core vesicle exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle docking IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle maturation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle priming IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuromuscular junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynaptic active zone cytoplasmic component IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in terminal bouton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein unc-13 homolog B

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Trachypithecus francoisi Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Tfra_2.0 Primary Assembly

    Genomic

    1. NW_022681461.1 Reference Tfra_2.0 Primary Assembly

      Range
      92315217..92488832 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033238183.1 → XP_033094074.1  protein unc-13 homolog B isoform X1

      Related
      ENSTFRP00000019429.1, ENSTFRT00000024416.1
      Conserved Domains (6) summary
      cd04027
      Location:3299 → 3425
      C2B_Munc13; C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins
      cd08395
      Location:4138 → 4257
      C2C_Munc13; C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins
      pfam06292
      Location:3617 → 3721
      DUF1041; Domain of Unknown Function (DUF1041)
      pfam10540
      Location:3964 → 4100
      Membr_traf_MHD; Munc13 (mammalian uncoordinated) homology domain
      cd20859
      Location:3158 → 3239
      C1_Munc13-2-like; protein kinase C conserved region 1 (C1 domain) found in Munc13-2, Munc13-3 and similar proteins
      cl14603
      Location:1 → 78
      C2; C2 domain

    2. XM_033238185.1 → XP_033094076.1  protein unc-13 homolog B isoform X3

      Conserved Domains (6) summary
      cd04027
      Location:551 → 677
      C2B_Munc13; C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins
      cd08395
      Location:1390 → 1509
      C2C_Munc13; C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins
      pfam06292
      Location:869 → 973
      DUF1041; Domain of Unknown Function (DUF1041)
      pfam10540
      Location:1216 → 1352
      Membr_traf_MHD; Munc13 (mammalian uncoordinated) homology domain
      cd20859
      Location:410 → 491
      C1_Munc13-2-like; protein kinase C conserved region 1 (C1 domain) found in Munc13-2, Munc13-3 and similar proteins
      cl14603
      Location:1 → 78
      C2; C2 domain

    3. XM_033238186.1 → XP_033094077.1  protein unc-13 homolog B isoform X4

      Related
      ENSTFRP00000019457.1, ENSTFRT00000024457.1
      Conserved Domains (6) summary
      cd04027
      Location:551 → 677
      C2B_Munc13; C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins
      cd08395
      Location:1409 → 1528
      C2C_Munc13; C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins
      pfam06292
      Location:869 → 973
      DUF1041; Domain of Unknown Function (DUF1041)
      pfam10540
      Location:1216 → 1352
      Membr_traf_MHD; Munc13 (mammalian uncoordinated) homology domain
      cd20859
      Location:410 → 491
      C1_Munc13-2-like; protein kinase C conserved region 1 (C1 domain) found in Munc13-2, Munc13-3 and similar proteins
      cl14603
      Location:1 → 78
      C2; C2 domain

    4. XM_033238184.1 → XP_033094075.1  protein unc-13 homolog B isoform X2

      Conserved Domains (6) summary
      cd04027
      Location:551 → 677
      C2B_Munc13; C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins
      cd08395
      Location:1408 → 1527
      C2C_Munc13; C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins
      pfam06292
      Location:869 → 972
      DUF1041; Domain of Unknown Function (DUF1041)
      pfam10540
      Location:1215 → 1351
      Membr_traf_MHD; Munc13 (mammalian uncoordinated) homology domain
      cd20859
      Location:410 → 491
      C1_Munc13-2-like; protein kinase C conserved region 1 (C1 domain) found in Munc13-2, Munc13-3 and similar proteins
      cl14603
      Location:1 → 78
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version

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