sup-26 RRM domain-containing protein [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: sup-26
Official Full Name: RRM domain-containing protein
Primary source: WormBase:WBGene00006331
Locus tag: CELE_R10E4.2
See related: AllianceGenome:WB:WBGene00006331
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Enables mRNA 3'-UTR binding activity. Involved in negative regulation of translation. Located in cytoplasm. Is expressed in several structures, including germ line and gonad. Orthologous to human RBMS1 (RNA binding motif single stranded interacting protein 1); RBMS2 (RNA binding motif single stranded interacting protein 2); and RBMS3 (RNA binding motif single stranded interacting protein 3). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See sup-26 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 6

Sequence:: Chromosome: III; NC_003281.10 (4276196..4280224, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that RNA binding proteins sup-26 and shep are required for the development of diverse cell types within the nematode and fly nervous systems during embryonic and larval stages.
Title: Drosophila Shep and C. elegans SUP-26 are RNA-binding proteins that play diverse roles in nervous system development.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

STS3-135 (e-PCR)
- UniSTS:241975

R10E4.2 (e-PCR)
- UniSTS:305874

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA 3'-UTR binding	IBA Inferred from Biological aspect of Ancestor more info
enables mRNA 3'-UTR binding	IDA Inferred from Direct Assay more info	PubMed
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables poly(A) binding	IBA Inferred from Biological aspect of Ancestor more info
enables poly(U) RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of translation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: RRM domain-containing protein

NP_001022716.1

Confirmed by transcript evidence

NP_001254892.1

Confirmed by transcript evidence

NP_001254893.1

Confirmed by transcript evidence

NP_001254894.1

Confirmed by transcript evidence

NP_001254898.1

Confirmed by transcript evidence

NP_001254900.1

Confirmed by transcript evidence

NP_001254903.1

Confirmed by transcript evidence

NP_001364668.1

Confirmed by transcript evidence

NP_001367243.1

Confirmed by transcript evidence

NP_001367244.1

Partially confirmed by transcript evidence

NP_001367245.1

Confirmed by transcript evidence

NP_001367246.1

Confirmed by transcript evidence

NP_001379085.1

Confirmed by transcript evidence

NP_001379516.1

Confirmed by transcript evidence

NP_001379517.1

Confirmed by transcript evidence

NP_497855.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

4276196..4280224 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001267971.4 → NP_001254900.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCQ1

Conserved Domains (2) summary

cd12243
Location:81 → 151

RRM1_MSSP; RNA recognition motif 1 in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:162 → 243

RRM2_MSSP; RNA recognition motif 2 in the c-myc gene single-strand binding proteins (MSSP) family
NM_001381832.2 → NP_001367243.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCQ3

Conserved Domains (3) summary

TIGR01648
Location:141 → 405

hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family

cd12243
Location:107 → 177

RRM1_MSSP; RNA recognition motif 1 (RRM1) found in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:188 → 269

RRM2_MSSP; RNA recognition motif 2 (RRM2) found in the c-myc gene single-strand binding proteins (MSSP) family
NM_001393318.1 → NP_001379516.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCQ2

Conserved Domains (3) summary

TIGR01648
Location:141 → 379

hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family

cd12243
Location:107 → 177

RRM1_MSSP; RNA recognition motif 1 (RRM1) found in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:188 → 269

RRM2_MSSP; RNA recognition motif 2 (RRM2) found in the c-myc gene single-strand binding proteins (MSSP) family
NM_065454.7 → NP_497855.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q21900

Conserved Domains (2) summary

cd12243
Location:107 → 177

RRM1_MSSP; RNA recognition motif 1 in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:188 → 269

RRM2_MSSP; RNA recognition motif 2 in the c-myc gene single-strand binding proteins (MSSP) family
NM_001267974.3 → NP_001254903.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCP9
NM_001393317.1 → NP_001379085.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q7JMB8

Conserved Domains (2) summary

cd12243
Location:81 → 151

RRM1_MSSP; RNA recognition motif 1 (RRM1) found in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:162 → 243

RRM2_MSSP; RNA recognition motif 2 (RRM2) found in the c-myc gene single-strand binding proteins (MSSP) family
NM_001267963.3 → NP_001254892.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCR3

Conserved Domains (2) summary

cd12243
Location:148 → 218

RRM1_MSSP; RNA recognition motif 1 in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:229 → 310

RRM2_MSSP; RNA recognition motif 2 in the c-myc gene single-strand binding proteins (MSSP) family
NM_001267964.3 → NP_001254893.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCR5

Conserved Domains (2) summary

cd12243
Location:43 → 113

RRM1_MSSP; RNA recognition motif 1 in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:124 → 205

RRM2_MSSP; RNA recognition motif 2 in the c-myc gene single-strand binding proteins (MSSP) family
NM_001267965.3 → NP_001254894.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCQ8

Conserved Domains (2) summary

cd12243
Location:43 → 113

RRM1_MSSP; RNA recognition motif 1 in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:124 → 205

RRM2_MSSP; RNA recognition motif 2 in the c-myc gene single-strand binding proteins (MSSP) family
NM_001381827.1 → NP_001367246.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCQ7

Conserved Domains (2) summary

cd12243
Location:81 → 151

RRM1_MSSP; RNA recognition motif 1 (RRM1) found in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:162 → 243

RRM2_MSSP; RNA recognition motif 2 (RRM2) found in the c-myc gene single-strand binding proteins (MSSP) family
NM_001381828.3 → NP_001367245.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCQ6

Conserved Domains (2) summary

cd12243
Location:107 → 177

RRM1_MSSP; RNA recognition motif 1 (RRM1) found in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:188 → 269

RRM2_MSSP; RNA recognition motif 2 (RRM2) found in the c-myc gene single-strand binding proteins (MSSP) family
NM_001381829.1 → NP_001367244.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCQ5

Conserved Domains (2) summary

cd12243
Location:107 → 177

RRM1_MSSP; RNA recognition motif 1 (RRM1) found in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:188 → 269

RRM2_MSSP; RNA recognition motif 2 (RRM2) found in the c-myc gene single-strand binding proteins (MSSP) family
NM_001267969.1 → NP_001254898.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCR4

Conserved Domains (2) summary

cd12243
Location:148 → 218

RRM1_MSSP; RNA recognition motif 1 in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:229 → 310

RRM2_MSSP; RNA recognition motif 2 in the c-myc gene single-strand binding proteins (MSSP) family
NM_001027545.4 → NP_001022716.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q7Z204
NM_001393316.1 → NP_001379517.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCQ4

Conserved Domains (3) summary

TIGR01648
Location:77 → 315

hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family

cd12243
Location:43 → 113

RRM1_MSSP; RNA recognition motif 1 (RRM1) found in the c-myc gene single-strand binding proteins (MSSP) family

cd12244
Location:124 → 205

RRM2_MSSP; RNA recognition motif 2 (RRM2) found in the c-myc gene single-strand binding proteins (MSSP) family
NM_001377919.2 → NP_001364668.1 RRM domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

D5MCQ0