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    T20D3.6 HIG1 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177762, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T20D3.6
    Official Full Name
    HIG1 domain-containing protein
    Primary source
    WormBase:WBGene00011859
    Locus tag
    CELE_T20D3.6
    See related
    AllianceGenome:WB:WBGene00011859
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial respirasome assembly. Located in cytoplasm. Orthologous to several human genes including HIGD2A (HIG1 hypoxia inducible domain family member 2A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T20D3.6 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (9338587..9339305, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Cytochrome Oxidase Assembly subunits Neighboring gene CHCH domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Solute carrier family 25 member 51 Neighboring gene Vacuolar protein sorting-associated protein 26 Neighboring gene Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial respirasome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    HIG1 domain-containing protein
    NP_001293845.1
    • Confirmed by transcript evidence
    NP_501643.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      9338587..9339305 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069242.5 → NP_501643.1  HIG1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501643.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01257
      Conserved Domains (1) summary
      pfam04588
      Location:55 → 105
      HIG_1_N; Hypoxia induced protein conserved region

    2. NM_001306916.3 → NP_001293845.1  HIG1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293845.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      S6F503
      Conserved Domains (1) summary
      pfam04588
      Location:21 → 71
      HIG_1_N; Hypoxia induced protein conserved region
    Nucleotide Protein
    Heading Accession and Version

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