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    pqn-87 MATH domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174861, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pqn-87
    Official Full Name
    MATH domain-containing protein
    Primary source
    WormBase:WBGene00004167
    Locus tag
    CELE_Y57A10A.18
    See related
    AllianceGenome:WB:WBGene00004167
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable chromatin DNA binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of DNA-templated transcription. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pqn-87 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    15
    Sequence:
    Chromosome: II; NC_003280.10 (12209095..12225086, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene DNA-directed DNA polymerase Neighboring gene Trafficking protein particle complex subunit 5 Neighboring gene AQuaPorin or aquaglyceroporin related Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SRRM2 protein homolog rsr-2 Neighboring gene Stress-activated map kinase-interacting protein 1 homolog Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article
    2. ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1. Wang W, et al. Traffic, 2008 May. PMID 18298590, Free PMC Article
    3. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Kolundzic E, et al. Dev Cell, 2018 Sep 10. PMID 30078731, Free PMC Article
    4. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
    5. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables chromatin DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription coactivator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MATH domain-containing protein
    NP_001254335.1
    • Partially confirmed by transcript evidence
    NP_001254336.1
    • Partially confirmed by transcript evidence
    NP_001367160.1
    • Confirmed by transcript evidence
    NP_001368162.1
    • Confirmed by transcript evidence
    NP_496594.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12209095..12225086 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381625.2 → NP_001367160.1  MATH domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5PEX6
      Conserved Domains (2) summary
      PTZ00121
      Location:802 → 1136
      PTZ00121; MAEBL; Provisional
      cd03772
      Location:174 → 311
      MATH_HAUSP; Herpesvirus-associated ubiquitin-specific protease (HAUSP, also known as USP7) family, N-terminal MATH (TRAF-like) domain; composed of proteins similar to human HAUSP, an enzyme that specifically catalyzes the deubiquitylation of p53 and MDM2, hence ...

    2. NM_064193.4 → NP_496594.2  MATH domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496594.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U207
      Conserved Domains (2) summary
      PTZ00121
      Location:802 → 1136
      PTZ00121; MAEBL; Provisional
      cd03772
      Location:174 → 311
      MATH_HAUSP; Herpesvirus-associated ubiquitin-specific protease (HAUSP, also known as USP7) family, N-terminal MATH (TRAF-like) domain; composed of proteins similar to human HAUSP, an enzyme that specifically catalyzes the deubiquitylation of p53 and MDM2, hence ...

    3. NM_001381626.2 → NP_001368162.1  MATH domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      K8ESL3
      Conserved Domains (2) summary
      PTZ00121
      Location:829 → 1163
      PTZ00121; MAEBL; Provisional
      cd03772
      Location:174 → 311
      MATH_HAUSP; Herpesvirus-associated ubiquitin-specific protease (HAUSP, also known as USP7) family, N-terminal MATH (TRAF-like) domain; composed of proteins similar to human HAUSP, an enzyme that specifically catalyzes the deubiquitylation of p53 and MDM2, hence ...

    4. NM_001267407.4 → NP_001254336.1  MATH domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254336.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G2HK02
      Conserved Domains (2) summary
      PTZ00121
      Location:825 → 1159
      PTZ00121; MAEBL; Provisional
      cd03772
      Location:174 → 311
      MATH_HAUSP; Herpesvirus-associated ubiquitin-specific protease (HAUSP, also known as USP7) family, N-terminal MATH (TRAF-like) domain; composed of proteins similar to human HAUSP, an enzyme that specifically catalyzes the deubiquitylation of p53 and MDM2, hence ...

    5. NM_001267406.4 → NP_001254335.1  MATH domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254335.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G2HK03
      Conserved Domains (2) summary
      PTZ00121
      Location:828 → 1162
      PTZ00121; MAEBL; Provisional
      cd03772
      Location:174 → 311
      MATH_HAUSP; Herpesvirus-associated ubiquitin-specific protease (HAUSP, also known as USP7) family, N-terminal MATH (TRAF-like) domain; composed of proteins similar to human HAUSP, an enzyme that specifically catalyzes the deubiquitylation of p53 and MDM2, hence ...
    Nucleotide Protein
    Heading Accession and Version

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