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    warf-1 ADP-ribosylation factor 1-like 1 [ Caenorhabditis elegans ]

    Gene ID: 191609, updated on 9-Dec-2024

    Summary

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    Official Symbol
    warf-1
    Official Full Name
    ADP-ribosylation factor 1-like 1
    Primary source
    WormBase:WBGene00000190
    Locus tag
    CELE_F45E4.1
    See related
    AllianceGenome:WB:WBGene00000190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTP binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in Golgi membrane. Predicted to be active in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See warf-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (7634786..7635712)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene EGF-like domain-containing protein Neighboring gene ncRNA Neighboring gene Transcriptional activator plp-1 Neighboring gene Peptidase M13 N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interaction of ARF-1.1 and neuronal calcium sensor-1 in the control of the temperature-dependency of locomotion in Caenorhabditis elegans. Todd PA, et al. Sci Rep, 2016 Jul 20. PMID 27435667, Free PMC Article
    2. Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome. Fan Y, et al. Nat Genet, 2004 Sep. PMID 15314642
    3. Galphao/i and Galphas signaling function in parallel with the MSP/Eph receptor to control meiotic diapause in C. elegans. Govindan JA, et al. Curr Biol, 2006 Jul 11. PMID 16824915
    4. Involvement of the actin cytoskeleton and homotypic membrane fusion in ER dynamics in Caenorhabditis elegans. Poteryaev D, et al. Mol Biol Cell, 2005 May. PMID 15716356, Free PMC Article
    5. GTPase-mediated regulation of the unfolded protein response in Caenorhabditis elegans is dependent on the AAA+ ATPase CDC-48. Caruso ME, et al. Mol Cell Biol, 2008 Jul. PMID 18458060, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in IRE1-mediated unfolded protein response HEP PubMed 
    involved_in endoplasmic reticulum unfolded protein response HEP PubMed 
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ADP-ribosylation factor 1-like 1
    NP_501242.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7634786..7635712
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068841.7 → NP_501242.1  ADP-ribosylation factor 1-like 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501242.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94231
      Conserved Domains (2) summary
      smart00178
      Location:1 → 175
      SAR; Sar1p-like members of the Ras-family of small GTPases
      cd00878
      Location:19 → 176
      Arf_Arl; ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94231.3

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