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    nhr-142 Nuclear Hormone Receptor family [ Caenorhabditis elegans ]

    Gene ID: 185740, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nhr-142
    Official Full Name
    Nuclear Hormone Receptor family
    Primary source
    WormBase:WBGene00018430
    Locus tag
    CELE_F44E7.8
    See related
    AllianceGenome:WB:WBGene00018430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nhr-142 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (5785957..5790553, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene F-box domain-containing protein Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene ncRNA Neighboring gene Rab5-interacting protein Neighboring gene N-acetylgalactosaminide beta-1,3-galactosyltransferase Neighboring gene UDP-galactose transporter

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A gene-centered C. elegans protein-DNA interaction network provides a framework for functional predictions. Fuxman Bass JI, et al. Mol Syst Biol, 2016 Oct 24. PMID 27777270, Free PMC Article
    2. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin. Karengera A, et al. Ecotoxicol Environ Saf, 2022 Mar 15. PMID 35219257
    3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nuclear Hormone Receptor family
    NP_001263836.1
    • Product from WormBase gene class nhr;
      Confirmed by transcript evidence
    NP_504518.3
    • Product from WormBase gene class nhr;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5785957..5790553 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001276907.4 → NP_001263836.1  Nuclear Hormone Receptor family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263836.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      J7SF93
      Conserved Domains (2) summary
      smart00399
      Location:50 → 119
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
      pfam00104
      Location:212 → 413
      Hormone_recep; Ligand-binding domain of nuclear hormone receptor

    2. NM_072117.5 → NP_504518.3  Nuclear Hormone Receptor family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504518.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MXK0
      Conserved Domains (2) summary
      smart00399
      Location:26 → 95
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
      pfam00104
      Location:188 → 394
      Hormone_recep; Ligand-binding domain of nuclear hormone receptor
    Nucleotide Protein
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