Lyc2 lysozyme C type 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Lyc2provided by RGD
Full Name: lysozyme C type 2provided by RGD
Primary source: RGD:1593616
See related: EnsemblRapid:ENSRNOG00000034139 AllianceGenome:RGD:1593616
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Lyz2
Summary: Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Predicted to be located in extracellular region. Orthologous to human LYZ (lysozyme). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Lung (RPKM 19666.0) and Spleen (RPKM 1647.9) See more
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Genomic context

Location:: 7q22

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (54773009..54780352)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (52887104..52894447)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (60316045..60323610)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH127643 (e-PCR)
- UniSTS:210953

D7MGH22 (e-PCR)
- UniSTS:120500

RH127838 (e-PCR)
- UniSTS:211148

RH94553 (e-PCR)
- UniSTS:119801

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables lysozyme activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in defense response to Gram-negative bacterium	IBA Inferred from Biological aspect of Ancestor more info
involved_in defense response to Gram-positive bacterium	IBA Inferred from Biological aspect of Ancestor more info
involved_in killing of cells of another organism	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative lysozyme C-2

Names: 1,4-beta-N-acetylmuramidase C

NP_001381322.1

EC 3.2.1.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001394393.1 → NP_001381322.1 putative lysozyme C-2 precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000007

UniProtKB/Swiss-Prot

Q05820

UniProtKB/TrEMBL

A6IGS3

Conserved Domains (1) summary

smart00263
Location:19 → 147

LYZ1; Alpha-lactalbumin / lysozyme C