U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    ST18 ST18 C2H2C-type zinc finger transcription factor [ Homo sapiens (human) ]

    Gene ID: 9705, updated on 9-Dec-2024

    Summary

    Official Symbol
    ST18provided by HGNC
    Official Full Name
    ST18 C2H2C-type zinc finger transcription factorprovided by HGNC
    Primary source
    HGNC:HGNC:18695
    See related
    Ensembl:ENSG00000147488 MIM:617155; AllianceGenome:HGNC:18695
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NZF3; NZF-3; ZNF387; ZC2H2C3; ZC2HC10
    Summary
    Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cytokine-mediated signaling pathway; negative regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Located in nucleus. Part of protein-DNA complex. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in brain (RPKM 3.7), stomach (RPKM 0.7) and 3 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ST18 in Genome Data Viewer
    Location:
    8q11.23
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (52110838..52409879, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (52486561..52785956, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (53023398..53322439, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27339 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27340 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27341 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr8:52837590-52838789 Neighboring gene PCMTD1 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19187 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27342 Neighboring gene uncharacterized LOC124901944 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27343 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:52959497-52959996 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:53013330-53014276 Neighboring gene uncharacterized LOC124901945 Neighboring gene uncharacterized LOC101929341 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:53125987-53126195 Neighboring gene VISTA enhancer hs698 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_103338 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27344 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27345 Neighboring gene MPRA-validated peak7016 silencer Neighboring gene ribosomal protein L34 pseudogene 17 Neighboring gene ST18-FAM150A intergenic CAGE-defined low expression enhancer Neighboring gene MED14-independent group 3 enhancer GRCh37_chr8:53458378-53459577 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:53476246-53477222 Neighboring gene MPRA-validated peak7018 silencer Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr8:53512288-53512788 Neighboring gene ALK and LTK ligand 1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:53541841-53542555 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr8:53566637-53567138 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr8:53567139-53567638 Neighboring gene RB1 inducible coiled-coil 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19188 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19189 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19190 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19191

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA0535

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in chromatin ISA
    Inferred from Sequence Alignment
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of protein-DNA complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    suppression of tumorigenicity 18 protein
    Names
    ST18, C2H2C-type zinc finger
    neural zinc finger transcription factor 3
    suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
    suppression of tumorigenicity 18, zinc finger
    zinc finger protein 387

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001352826.2NP_001339755.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    2. NM_001352827.2NP_001339756.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    3. NM_001352828.2NP_001339757.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Related
      ENSP00000514122.1, ENST00000699087.1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    4. NM_001352829.2NP_001339758.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    5. NM_001352830.2NP_001339759.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    6. NM_001352831.2NP_001339760.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Related
      ENSP00000508476.1, ENST00000693301.1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    7. NM_001352832.2NP_001339761.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    8. NM_001352833.2NP_001339762.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    9. NM_001352834.2NP_001339763.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    10. NM_001352835.2NP_001339764.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    11. NM_001352836.2NP_001339765.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    12. NM_001352837.2NP_001339766.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Related
      ENSP00000509475.1, ENST00000689386.1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    13. NM_001352838.2NP_001339767.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915, AC103831
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    14. NM_001352839.2NP_001339768.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (15) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    15. NM_001352840.2NP_001339769.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (16) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    16. NM_001352841.2NP_001339770.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (17) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    17. NM_001352842.2NP_001339771.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (18) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    18. NM_001352843.2NP_001339772.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (19) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    19. NM_001352844.2NP_001339773.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (20) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    20. NM_001352845.2NP_001339774.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (21) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    21. NM_001352846.2NP_001339775.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (22) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    22. NM_001352847.2NP_001339776.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (23) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    23. NM_001352848.2NP_001339777.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (24) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    24. NM_001352849.2NP_001339778.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (25) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    25. NM_001352850.2NP_001339779.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (26) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    26. NM_001352851.2NP_001339780.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (27) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    27. NM_001352852.2NP_001339781.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (28) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    28. NM_001352853.2NP_001339782.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (29) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    29. NM_001352854.2NP_001339783.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (30) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    30. NM_001352855.2NP_001339784.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (31) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    31. NM_001352856.2NP_001339785.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (32) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    32. NM_001352857.2NP_001339786.1  suppression of tumorigenicity 18 protein isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (33) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AC021915
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    33. NM_001352858.2NP_001339787.1  suppression of tumorigenicity 18 protein isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (43) encodes isoform c. Variants 43-45 all encode isoform c.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:738766
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:450686
      MYT1; Myelin transcription factor 1
      cl25732
      Location:892963
      SMC_N; RecF/RecN/SMC N terminal domain
    34. NM_001352859.2NP_001339788.1  suppression of tumorigenicity 18 protein isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (44) encodes isoform c. Variants 43-45 all encode isoform c.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:738766
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:450686
      MYT1; Myelin transcription factor 1
      cl25732
      Location:892963
      SMC_N; RecF/RecN/SMC N terminal domain
    35. NM_001352860.2NP_001339789.1  suppression of tumorigenicity 18 protein isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (45) encodes isoform c. Variants 43-45 all encode isoform c.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:738766
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:450686
      MYT1; Myelin transcription factor 1
      cl25732
      Location:892963
      SMC_N; RecF/RecN/SMC N terminal domain
    36. NM_001352861.2NP_001339790.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (34) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:732760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886957
      SMC_N; RecF/RecN/SMC N terminal domain
    37. NM_001352862.2NP_001339791.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (35) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:732760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886957
      SMC_N; RecF/RecN/SMC N terminal domain
    38. NM_001352863.2NP_001339792.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (36) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:732760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886957
      SMC_N; RecF/RecN/SMC N terminal domain
    39. NM_001352864.2NP_001339793.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (37) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886957
      SMC_N; RecF/RecN/SMC N terminal domain
    40. NM_001352865.2NP_001339794.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (38) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886957
      SMC_N; RecF/RecN/SMC N terminal domain
    41. NM_001352866.2NP_001339795.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (39) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886957
      SMC_N; RecF/RecN/SMC N terminal domain
    42. NM_001352867.2NP_001339796.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (40) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886957
      SMC_N; RecF/RecN/SMC N terminal domain
    43. NM_001352868.2NP_001339797.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (41) encodes isoform b. Variants 34-42 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886957
      SMC_N; RecF/RecN/SMC N terminal domain
    44. NM_001352869.2NP_001339798.1  suppression of tumorigenicity 18 protein isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (42) encodes isoform b. Variants 46-51 all encode isoform b.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:732760
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:444680
      MYT1; Myelin transcription factor 1
      cl25732
      Location:886957
      SMC_N; RecF/RecN/SMC N terminal domain
    45. NM_001352870.2NP_001339799.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (46) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:685713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839910
      SMC_N; RecF/RecN/SMC N terminal domain
    46. NM_001352871.2NP_001339800.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (47) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:685713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839910
      SMC_N; RecF/RecN/SMC N terminal domain
    47. NM_001352872.2NP_001339801.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (48) encodes isoform d. Variants 34-42 all encode isoform d.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:685713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839910
      SMC_N; RecF/RecN/SMC N terminal domain
    48. NM_001352873.2NP_001339802.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (49) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:685713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839910
      SMC_N; RecF/RecN/SMC N terminal domain
    49. NM_001352874.2NP_001339803.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (50) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:685713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839910
      SMC_N; RecF/RecN/SMC N terminal domain
    50. NM_001352875.2NP_001339804.1  suppression of tumorigenicity 18 protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (51) encodes isoform d. Variants 46-51 all encode isoform d.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:685713
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479633
      MYT1; Myelin transcription factor 1
      cl25732
      Location:839910
      SMC_N; RecF/RecN/SMC N terminal domain
    51. NM_001352876.2NP_001339805.1  suppression of tumorigenicity 18 protein isoform f

      Status: VALIDATED

      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:421449
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:215369
      MYT1; Myelin transcription factor 1
      cl25732
      Location:575646
      SMC_N; RecF/RecN/SMC N terminal domain
    52. NM_001352877.2NP_001339806.1  suppression of tumorigenicity 18 protein isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (52) encodes isoform e. Variants 52 and 53 both encode isoform e.
      Source sequence(s)
      AC021915, AC103831
      Conserved Domains (3) summary
      pfam01530
      Location:414442
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:126362
      MYT1; Myelin transcription factor 1
      cl25732
      Location:568639
      SMC_N; RecF/RecN/SMC N terminal domain
    53. NM_001352878.2NP_001339807.1  suppression of tumorigenicity 18 protein isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (53) encodes isoform e. Variants 52 and 53 both encode isoform e.
      Source sequence(s)
      AC021915
      Conserved Domains (3) summary
      pfam01530
      Location:414442
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:126362
      MYT1; Myelin transcription factor 1
      cl25732
      Location:568639
      SMC_N; RecF/RecN/SMC N terminal domain
    54. NM_001352879.1NP_001339808.1  suppression of tumorigenicity 18 protein isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (55) encodes isoform g. Variants 55-58 all encode isoform g.
      Source sequence(s)
      AC103831
    55. NM_001352880.1NP_001339809.1  suppression of tumorigenicity 18 protein isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (56) encodes isoform g. Variants 55-58 all encode isoform g.
      Source sequence(s)
      AC103831
    56. NM_001352881.1NP_001339810.1  suppression of tumorigenicity 18 protein isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (57) encodes isoform g. Variants 55-58 all encode isoform g.
      Source sequence(s)
      AC021915, AC103831
    57. NM_001352882.1NP_001339811.1  suppression of tumorigenicity 18 protein isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (58) encodes isoform g. Variants 55-58 all encode isoform g.
      Source sequence(s)
      AC103831
    58. NM_001352883.2NP_001339812.1  suppression of tumorigenicity 18 protein isoform h

      Status: VALIDATED

      Description
      Transcript Variant: This variant (59) encodes isoform h. Variants 59 and 60 both encode isoform h.
      Source sequence(s)
      AC103831
      Related
      ENST00000522102.5
    59. NM_001352884.2NP_001339813.1  suppression of tumorigenicity 18 protein isoform h

      Status: VALIDATED

      Description
      Transcript Variant: This variant (60) encodes isoform h. Variants 59 and 60 both encode isoform h.
      Source sequence(s)
      AC103831
    60. NM_014682.3NP_055497.1  suppression of tumorigenicity 18 protein isoform a

      See identical proteins and their annotated locations for NP_055497.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform a. Variants 1-33 all encode isoform a.
      Source sequence(s)
      AB011107, BC117147, BQ639545, DA288225
      Consensus CDS
      CCDS6149.1
      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Related
      ENSP00000276480.7, ENST00000276480.11
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain

    RNA

    1. NR_148195.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC021915, AC103831
    2. NR_148196.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC021915

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      52110838..52409879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047422485.1XP_047278441.1  suppression of tumorigenicity 18 protein isoform X2

    2. XM_047422486.1XP_047278442.1  suppression of tumorigenicity 18 protein isoform X2

    3. XM_047422487.1XP_047278443.1  suppression of tumorigenicity 18 protein isoform X2

    4. XM_024447349.2XP_024303117.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    5. XM_047422484.1XP_047278440.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1
    6. XM_017014058.2XP_016869547.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1
      Conserved Domains (3) summary
      pfam01530
      Location:767795
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:479715
      MYT1; Myelin transcription factor 1
      cl25732
      Location:921992
      SMC_N; RecF/RecN/SMC N terminal domain
    7. XM_024447350.2XP_024303118.1  suppression of tumorigenicity 18 protein isoform X3

      Conserved Domains (3) summary
      pfam01530
      Location:414442
      zf-C2HC; Zinc finger, C2HC type
      pfam08474
      Location:126362
      MYT1; Myelin transcription factor 1
      cl25732
      Location:568639
      SMC_N; RecF/RecN/SMC N terminal domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      52486561..52785956 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054361604.1XP_054217579.1  suppression of tumorigenicity 18 protein isoform X2

    2. XM_054361605.1XP_054217580.1  suppression of tumorigenicity 18 protein isoform X2

    3. XM_054361606.1XP_054217581.1  suppression of tumorigenicity 18 protein isoform X2

    4. XM_054361602.1XP_054217577.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1
    5. XM_054361601.1XP_054217576.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1
    6. XM_054361603.1XP_054217578.1  suppression of tumorigenicity 18 protein isoform X1

      UniProtKB/Swiss-Prot
      O60284, Q17RY1
    7. XM_054361607.1XP_054217582.1  suppression of tumorigenicity 18 protein isoform X3