U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    Or10al2 olfactory receptor family 10 subfamily AL member 2 [ Mus musculus (house mouse) ]

    Gene ID: 404308, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Or10al2provided by MGI
    Official Full Name
    olfactory receptor family 10 subfamily AL member 2provided by MGI
    Primary source
    MGI:MGI:2177501
    See related
    Ensembl:ENSMUSG00000080990 AllianceGenome:MGI:2177501
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr118; MOR263-13
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Or10al2 in Genome Data Viewer
    Location:
    17 B1; 17 19.16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (37982916..37983888)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (37672025..37672990)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 14 subfamily J member 10 Neighboring gene olfactory receptor family 2 subfamily G member 25 Neighboring gene olfactory receptor family 10 subfamily AL member 3 Neighboring gene Scoc pseudogene

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex. Amadou C, et al. Hum Mol Genet, 2003 Nov 15. PMID 14506126
    2. Odorant and vomeronasal receptor genes in two mouse genome assemblies. Zhang X, et al. Genomics, 2004 May. PMID 15081110
    3. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    4. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
    5. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC157604

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    olfactory receptor 118
    Names
    GA_x5J8B7TVMCU-697-290
    GA_x5J8B7TYMFE-883-533
    GA_x6K02T2PSCP-2131124-2132089

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213721.2 → NP_998886.2  olfactory receptor 118

      See identical proteins and their annotated locations for NP_998886.2

      Status: VALIDATED

      Source sequence(s)
      BC128012
      Consensus CDS
      CCDS28760.1
      UniProtKB/TrEMBL
      G5E8U0, Q6UAE3, Q7TRJ6
      Related
      ENSMUSP00000113988.2, ENSMUST00000122036.2
      Conserved Domains (2) summary
      pfam00001
      Location:47 → 296
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:39 → 314
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      37982916..37983888
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249887.2 → XP_030105747.1  olfactory receptor 118 isoform X1

      Conserved Domains (2) summary
      cd14964
      Location:32 → 58
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:31 → 167
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools