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    Gm14434 predicted gene 14434 [ Mus musculus (house mouse) ]

    Gene ID: 668039, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Gm14434provided by MGI
    Official Full Name
    predicted gene 14434provided by MGI
    Primary source
    MGI:MGI:3702417
    See related
    Ensembl:ENSMUSG00000078881 AllianceGenome:MGI:3702417
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF20 (zinc finger protein 20). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 7.6), bladder adult (RPKM 7.6) and 24 other tissues See more
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    Genomic context

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    See Gm14434 in Genome Data Viewer
    Location:
    2 H4; 2 98.91 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (176155593..176178644, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (176470369..176486853, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 11009 Neighboring gene RIKEN cDNA 2210418O10 gene Neighboring gene zinc finger protein 968, pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr2:176131206-176131506 Neighboring gene zinc finger protein 967 Neighboring gene predicted gene 14308

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
    5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    KRAB box and zinc finger, C2H2 type domain containing protein
    Names
    novel KRAB box and zinc finger, C2H2 type domain containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101804.1 → NP_001095274.1  KRAB box and zinc finger, C2H2 type domain containing protein

      See identical proteins and their annotated locations for NP_001095274.1

      Status: PROVISIONAL

      Source sequence(s)
      CR848808
      Consensus CDS
      CCDS57197.1
      UniProtKB/TrEMBL
      A2ART4
      Related
      ENSMUSP00000112478.3, ENSMUST00000122097.9
      Conserved Domains (3) summary
      COG5048
      Location:74 → 486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:217 → 237
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 44
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      176155593..176178644 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251964.2 → XP_030107824.1  KRAB box and zinc finger, C2H2 type domain containing protein isoform X3

      Conserved Domains (2) summary
      COG5048
      Location:42 → 454
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:185 → 205
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_036162486.1 → XP_036018379.1  KRAB box and zinc finger, C2H2 type domain containing protein isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:42 → 454
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:185 → 205
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_030251963.2 → XP_030107823.1  KRAB box and zinc finger, C2H2 type domain containing protein isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:42 → 454
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:185 → 205
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_030251962.2 → XP_030107822.1  KRAB box and zinc finger, C2H2 type domain containing protein isoform X1

      UniProtKB/TrEMBL
      A2ART4
      Conserved Domains (3) summary
      COG5048
      Location:74 → 486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:217 → 237
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 44
      KRAB; KRAB box

    5. XM_036162485.1 → XP_036018378.1  KRAB box and zinc finger, C2H2 type domain containing protein isoform X1

      UniProtKB/TrEMBL
      A2ART4
      Conserved Domains (3) summary
      COG5048
      Location:74 → 486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:217 → 237
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:3 → 44
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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