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    Zfp629 zinc finger protein 629 [ Mus musculus (house mouse) ]

    Gene ID: 320683, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp629provided by MGI
    Official Full Name
    zinc finger protein 629provided by MGI
    Primary source
    MGI:MGI:2444524
    See related
    Ensembl:ENSMUSG00000045639 AllianceGenome:MGI:2444524
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf629; 9330199A09Rik
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system; limb mesenchyme; nervous system; and retina layer. Orthologous to human ZNF629 (zinc finger protein 629). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 8.7), whole brain E14.5 (RPKM 7.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp629 in Genome Data Viewer
    Location:
    7 F3; 7 69.62 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (127206203..127215053, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127607028..127615785, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 40 Neighboring gene RIKEN cDNA 1700120K04 gene Neighboring gene predicted gene, 51458 Neighboring gene predicted gene, 53373

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
    2. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
    3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 629

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362196.2 → NP_001349125.1  zinc finger protein 629 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC122417
      Consensus CDS
      CCDS21873.1
      UniProtKB/Swiss-Prot
      Q6A085, Q8BG88, Q8BIR0
      Related
      ENSMUSP00000081612.4, ENSMUST00000084564.10
      Conserved Domains (3) summary
      COG5048
      Location:203 → 511
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:179 → 199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:149 → 171
      zf-C2H2; Zinc finger, C2H2 type

    2. NM_001362197.2 → NP_001349126.1  zinc finger protein 629 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC122417
      Consensus CDS
      CCDS21873.1
      UniProtKB/Swiss-Prot
      Q6A085, Q8BG88, Q8BIR0
      Related
      ENSMUSP00000113903.2, ENSMUST00000122066.8
      Conserved Domains (3) summary
      COG5048
      Location:203 → 511
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:179 → 199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:149 → 171
      zf-C2H2; Zinc finger, C2H2 type

    3. NM_001404400.1 → NP_001391329.1  zinc finger protein 629 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC122417
      UniProtKB/Swiss-Prot
      Q6A085, Q8BG88, Q8BIR0

    4. NM_001404402.1 → NP_001391331.1  zinc finger protein 629 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC122417
      UniProtKB/Swiss-Prot
      Q6A085, Q8BG88, Q8BIR0

    5. NM_001404403.1 → NP_001391332.1  zinc finger protein 629 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC122417
      UniProtKB/Swiss-Prot
      Q6A085, Q8BG88, Q8BIR0

    6. NM_001404404.1 → NP_001391333.1  zinc finger protein 629 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC122417
      UniProtKB/Swiss-Prot
      Q6A085, Q8BG88, Q8BIR0

    7. NM_001404405.1 → NP_001391334.1  zinc finger protein 629 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC122417

    8. NM_177226.7 → NP_796200.1  zinc finger protein 629 isoform a

      See identical proteins and their annotated locations for NP_796200.1

      Status: VALIDATED

      Source sequence(s)
      AC122417
      Consensus CDS
      CCDS21873.1
      UniProtKB/Swiss-Prot
      Q6A085, Q8BG88, Q8BIR0
      Related
      ENSMUSP00000053760.6, ENSMUST00000058038.12
      Conserved Domains (3) summary
      COG5048
      Location:203 → 511
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:179 → 199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:149 → 171
      zf-C2H2; Zinc finger, C2H2 type

    RNA

    1. NR_155450.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC122417

    2. NR_155451.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC122417

    3. NR_155452.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC122417

    4. NR_175840.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC122417

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      127206203..127215053 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241833.4 → XP_011240135.1  zinc finger protein 629 isoform X2

      See identical proteins and their annotated locations for XP_011240135.1

      UniProtKB/Swiss-Prot
      Q6A085, Q8BG88, Q8BIR0
      Conserved Domains (3) summary
      COG5048
      Location:203 → 511
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:179 → 199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:149 → 171
      zf-C2H2; Zinc finger, C2H2 type

    2. XM_006507952.4 → XP_006508015.1  zinc finger protein 629 isoform X1

      Conserved Domains (3) summary
      PHA03169
      Location:118 → 269
      PHA03169; hypothetical protein; Provisional
      COG5048
      Location:251 → 629
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:288 → 308
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6A085.2 GenPept UniProtKB/Swiss-Prot:Q6A085

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    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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