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    Mup7 major urinary protein 7 [ Mus musculus (house mouse) ]

    Gene ID: 100041658, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Mup7provided by MGI
    Official Full Name
    major urinary protein 7provided by MGI
    Primary source
    MGI:MGI:3709615
    See related
    Ensembl:ENSMUSG00000073842 AllianceGenome:MGI:3709615
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mup3; Gm12546
    Summary
    Predicted to enable odorant binding activity. Predicted to be active in extracellular space. Is expressed in liver. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward liver adult (RPKM 2011.5) See more
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    Genomic context

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    See Mup7 in Genome Data Viewer
    Location:
    4 B3; 4 32.82 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (60066469..60070481, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (60066469..60070475, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10391 Neighboring gene STARR-seq mESC enhancer starr_10392 Neighboring gene major urinary protein 4 Neighboring gene STARR-seq mESC enhancer starr_10394 Neighboring gene major urinary protein 6 Neighboring gene major urinary protein, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_10395 Neighboring gene STARR-seq mESC enhancer starr_10396 Neighboring gene major urinary protein 2 Neighboring gene major urinary protein, pseudogene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary protein gene expression in the mouse liver. Jiang J, et al. J Biol Chem, 2017 Apr 21. PMID 28258223, Free PMC Article
    2. Species specificity in major urinary proteins by parallel evolution. Logan DW, et al. PLoS One, 2008 Sep 25. PMID 18815613, Free PMC Article
    3. Identification of protein pheromones that promote aggressive behaviour. Chamero P, et al. Nature, 2007 Dec 6. PMID 18064011
    4. Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom". Charkoftaki G, et al. Hum Genomics, 2019 Feb 19. PMID 30782214, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    major urinary protein 7
    Names
    major urinary protein gene family member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347129.1 → NP_001334058.1  major urinary protein 7 precursor

      Status: VALIDATED

      Source sequence(s)
      AL772327
      Consensus CDS
      CCDS84739.1
      UniProtKB/TrEMBL
      B0V388, Q58EV3
      Related
      ENSMUSP00000078636.4, ENSMUST00000079697.10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      60066469..60070481 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253000.2 → XP_030108860.1  major urinary protein 7 isoform X1

      UniProtKB/TrEMBL
      E9QA79
      Related
      ENSMUSP00000130795.2, ENSMUST00000166098.8
      Conserved Domains (1) summary
      cd19428
      Location:23 → 172
      lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001134675.1: Suppressed sequence

      Description
      NM_001134675.1: This RefSeq was removed because currently there is insufficient support for the transcript.
    Nucleotide Protein Strain
    Heading Accession and Version

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