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    abu-14 Activated in Blocked Unfolded protein response [ Caenorhabditis elegans ]

    Gene ID: 174464, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abu-14
    Official Full Name
    Activated in Blocked Unfolded protein response
    Primary source
    WormBase:WBGene00004174
    Locus tag
    CELE_ZK1067.7
    See related
    AllianceGenome:WB:WBGene00004174
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in pharynx development. Is expressed in buccal cavity; cuticle; grinder; marginal cell; and pharyngeal muscle cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abu-14 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (9225186..9227214, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene NFX1-type zinc finger-containing protein 1 homolog Neighboring gene Uncharacterized protein Neighboring gene Glutathione S-transferase Neighboring gene Apple domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Oligosaccharides from agar extends lifespan through activation of unfolded protein response via SIR-2.1 in Caenorhabditis elegans. Desaka N, et al. Eur J Nutr, 2022 Dec. PMID 35864340
    2. Dynamically-expressed prion-like proteins form a cuticle in the pharynx of Caenorhabditis elegans. George-Raizen JB, et al. Biol Open, 2014 Oct 31. PMID 25361578, Free PMC Article
    3. Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes. Sun J, et al. Science, 2011 May 6. PMID 21474712, Free PMC Article
    4. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Viswanathan M, et al. Dev Cell, 2005 Nov. PMID 16256736
    5. Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Tewari M, et al. Mol Cell, 2004 Feb 27. PMID 14992718

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in pharynx development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Activated in Blocked Unfolded protein response
    NP_495966.2
    • Product from WormBase gene class abu;
      Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9225186..9227214 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063565.9 → NP_495966.2  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495966.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23390
      Conserved Domains (1) summary
      cl27295
      Location:178 → 261
      OATP; Organic Anion Transporter Polypeptide (OATP) family
    Nucleotide Protein
    Heading Accession and Version

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