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    tin-9.1 Mitochondrial import inner membrane translocase subunit Tim9 [ Caenorhabditis elegans ]

    Gene ID: 177475, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tin-9.1
    Official Full Name
    Mitochondrial import inner membrane translocase subunit Tim9
    Primary source
    WormBase:WBGene00006572
    Locus tag
    CELE_C06G3.11
    See related
    AllianceGenome:WB:WBGene00006572
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity. Involved in protein insertion into mitochondrial inner membrane and regulation of growth. Predicted to be located in mitochondrial inner membrane. Orthologous to human TIMM9 (translocase of inner mitochondrial membrane 9). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tin-9.1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_003282.8 (7044058..7044602, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Conserved oligomeric Golgi complex subunit 2 Neighboring gene Kinesin motor domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nuclear Hormone Receptor family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension. Schmeisser S, et al. Aging Cell, 2013 Jun. PMID 23534459, Free PMC Article
    2. Defective mitochondrial protein translocation precludes normal Caenorhabditis elegans development. Curran SP, et al. J Biol Chem, 2004 Dec 24. PMID 15485840
    3. Caenorhabditis elegans as a model system to study intercompartmental proteostasis: Interrelation of mitochondrial function, longevity, and neurodegenerative diseases. Kirstein-Miles J, et al. Dev Dyn, 2010 May. PMID 20419784, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein insertion into mitochondrial inner membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in reproductive process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Mitochondrial import inner membrane translocase subunit Tim9
    NP_001021307.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7044058..7044602 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026136.7 → NP_001021307.1  Mitochondrial import inner membrane translocase subunit Tim9 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021307.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q17754, Q86B35
      Conserved Domains (1) summary
      pfam02953
      Location:5 → 63
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    Nucleotide Protein
    Heading Accession and Version

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