mask-1 Ankyrin repeat and KH domain-containing protein mask-1;K Homology domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: mask-1
Official Full Name: Ankyrin repeat and KH domain-containing protein mask-1;K Homology domain-containing protein
Primary source: WormBase:WBGene00011240
Locus tag: CELE_R11A8.7
See related: AllianceGenome:WB:WBGene00011240
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity. Predicted to be located in cytoplasm. Is expressed in several structures, including hypodermis; intestine; nervous system; pharynx; and vulva. Orthologous to human ANKHD1-EIF4EBP3 (ANKHD1-EIF4EBP3 readthrough); ANKHD1 (ankyrin repeat and KH domain containing 1); and ANKRD17 (ankyrin repeat domain 17). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See mask-1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 24

Sequence:: Chromosome: IV; NC_003282.8 (10374901..10387318)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R11A8.7 (e-PCR)
- UniSTS:311575

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Ankyrin repeat and KH domain-containing protein mask-1;K Homology domain-containing protein

NP_001122794.1

Confirmed by transcript evidence

NP_001122795.1

Confirmed by transcript evidence

NP_001255486.1

Confirmed by transcript evidence

NP_001263772.1

Confirmed by transcript evidence

NP_001263773.1

Confirmed by transcript evidence

NP_001294023.1

Confirmed by transcript evidence

NP_001368167.1

Confirmed by transcript evidence

NP_001368487.1

Confirmed by transcript evidence

NP_501915.2

Confirmed by transcript evidence

NP_501916.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

10374901..10387318

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_069514.3 → NP_501915.2 Ankyrin repeat and KH domain-containing protein mask-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_501915.2

Status: REVIEWED

UniProtKB/Swiss-Prot

A3RMT6, A3RMT7, D3YT52, L8E837, L8E927, L8EC41, Q21920, Q21927, Q9TW88

Conserved Domains (4) summary

PHA03095
Location:1316 → 1545

PHA03095; ankyrin-like protein; Provisional

sd00045
Location:1267 → 1299

ANK; ANK repeat [structural motif]

pfam12796
Location:1241 → 1332

Ank_2; Ankyrin repeats (3 copies)

cd22462
Location:1810 → 1877

KH-I_HEN4_like_rpt5; fifth type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana KH domain-containing protein HEN4 and similar protein
NM_069515.4 → NP_501916.2 Ankyrin repeat and KH domain-containing protein mask-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_501916.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q21920

Conserved Domains (4) summary

cd00105
Location:1809 → 1873

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd00204
Location:1241 → 1355

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:1241 → 1332

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:1267 → 1299

ANK; ANK repeat [structural motif]
NM_001380446.2 → NP_001368167.1 Ankyrin repeat and KH domain-containing protein mask-1 [Caenorhabditis elegans]

Status: REVIEWED

Conserved Domains (4) summary

PHA03095
Location:203 → 432

PHA03095; ankyrin-like protein; Provisional

sd00045
Location:154 → 186

ANK; ANK repeat [structural motif]

pfam12796
Location:128 → 219

Ank_2; Ankyrin repeats (3 copies)

cl00098
Location:697 → 764

KH-I; K homology (KH) RNA-binding domain, type I
NM_001276844.3 → NP_001263773.1 Ankyrin repeat and KH domain-containing protein mask-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001263773.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q21920

Conserved Domains (4) summary

cd00105
Location:1811 → 1875

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd00204
Location:1243 → 1357

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:1243 → 1334

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:1269 → 1301

ANK; ANK repeat [structural motif]
NM_001276843.3 → NP_001263772.1 Ankyrin repeat and KH domain-containing protein mask-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001263772.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q21920

Conserved Domains (4) summary

cd00105
Location:1811 → 1875

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd00204
Location:1243 → 1357

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:1243 → 1334

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:1269 → 1301

ANK; ANK repeat [structural motif]
NM_001380445.1 → NP_001368487.1 K Homology domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A061AJK8

Conserved Domains (4) summary

PHA03095
Location:1322 → 1551

PHA03095; ankyrin-like protein; Provisional

sd00045
Location:1273 → 1305

ANK; ANK repeat [structural motif]

pfam12796
Location:1247 → 1338

Ank_2; Ankyrin repeats (3 copies)

cl00098
Location:1816 → 1883

KH-I; K homology (KH) RNA-binding domain, type I
NM_001307094.3 → NP_001294023.1 K Homology domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001294023.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A061AL89

Conserved Domains (4) summary

cd00105
Location:1813 → 1877

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd00204
Location:1245 → 1359

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:1245 → 1336

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:1271 → 1303

ANK; ANK repeat [structural motif]
NM_001268557.3 → NP_001255486.1 Ankyrin repeat and KH domain-containing protein mask-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001255486.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q21920

Conserved Domains (4) summary

cd00105
Location:694 → 758

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd00204
Location:126 → 240

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:126 → 217

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:152 → 184

ANK; ANK repeat [structural motif]
NM_001129323.4 → NP_001122795.1 Ankyrin repeat and KH domain-containing protein mask-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001122795.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q21920

Conserved Domains (4) summary

cd00105
Location:616 → 680

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd00204
Location:48 → 162

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:48 → 139

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:74 → 106

ANK; ANK repeat [structural motif]
NM_001129322.4 → NP_001122794.1 Ankyrin repeat and KH domain-containing protein mask-1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001122794.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q21920

Conserved Domains (4) summary

cd00105
Location:616 → 680

KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...

cd00204
Location:48 → 162

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam12796
Location:48 → 139

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:74 → 106

ANK; ANK repeat [structural motif]