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    F36D4.5 Desumoylating isopeptidase 1 homolog [ Caenorhabditis elegans ]

    Gene ID: 179324, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F36D4.5
    Official Full Name
    Desumoylating isopeptidase 1 homolog
    Primary source
    WormBase:WBGene00018090
    Locus tag
    CELE_F36D4.5
    See related
    AllianceGenome:WB:WBGene00018090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable deubiquitinase activity. Predicted to be involved in proteolysis. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including intestine; nervous system; pharyngeal-intestinal valve; rectal gland cell; and reproductive system. Orthologous to human DESI2 (desumoylating isopeptidase 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F36D4.5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (9419254..9425817, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Tyr Neighboring gene BLOC-1-related complex subunit 7 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Resolvase/invertase-type recombinase catalytic domain-containing protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Desumoylating isopeptidase 1 homolog
    NP_741591.1
    • Confirmed by transcript evidence
    NP_741592.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9419254..9425817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171506.2 → NP_741591.1  Desumoylating isopeptidase 1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741591.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2KZK4, Q8MNS8
      Conserved Domains (1) summary
      pfam05903
      Location:32 → 174
      Peptidase_C97; PPPDE putative peptidase domain

    2. NM_171507.8 → NP_741592.1  Desumoylating isopeptidase 1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741592.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MNS8
      Conserved Domains (1) summary
      pfam05903
      Location:13 → 155
      Peptidase_C97; PPPDE putative peptidase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    H2KZK4.1

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