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    atxn1.S ataxin 1 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 108720115, updated on 20-Nov-2024

    Summary

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    Official Symbol
    atxn1.S
    Official Full Name
    ataxin 1 S homeolog
    Primary source
    Xenbase:XB-GENE-17335803
    Locus tag
    XELAEV_18033487mg
    See related
    EnsemblRapid:ENSXLAG00005004335 AllianceGenome:Xenbase:XB-GENE-17335803
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    atx1
    Summary
    Predicted to enable DNA binding activity and RNA binding activity. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and nervous system development. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 1. Orthologous to human ATXN1 (ataxin 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See atxn1.S in Genome Data Viewer
    Location:
    chromosome: 6S
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6S NC_054382.1 (79803855..79983371)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6S NC_030735.1 (71789611..71968361)

    Chromosome 6S - NC_054382.1Genomic Context describing neighboring genes Neighboring gene stathmin domain containing 1 S homeolog Neighboring gene uncharacterized LOC121395140 Neighboring gene uncharacterized LOC121395141 Neighboring gene uncharacterized LOC121395142 Neighboring gene uncharacterized LOC121395143

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ataxin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054382.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      79803855..79983371
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041567756.1 → XP_041423690.1  ataxin-1

      UniProtKB/TrEMBL
      A0A1L8FSD1, A0A974CNS4, A0A974HE15
      Conserved Domains (2) summary
      pfam08517
      Location:546 → 657
      AXH; Ataxin-1 and HBP1 module (AXH)
      pfam12547
      Location:371 → 415
      ATXN-1_C; Capicua transcriptional repressor modulator

    2. XM_041567755.1 → XP_041423689.1  ataxin-1

      UniProtKB/TrEMBL
      A0A1L8FSD1, A0A974CNS4, A0A974HE15
      Conserved Domains (2) summary
      pfam08517
      Location:546 → 657
      AXH; Ataxin-1 and HBP1 module (AXH)
      pfam12547
      Location:371 → 415
      ATXN-1_C; Capicua transcriptional repressor modulator

    3. XM_018269505.2 → XP_018124994.1  ataxin-1

      UniProtKB/TrEMBL
      A0A1L8FSD1, A0A974CNS4, A0A974HE15
      Related
      ENSXLAP00005012964.1, ENSXLAT00005013144.1
      Conserved Domains (2) summary
      pfam08517
      Location:546 → 657
      AXH; Ataxin-1 and HBP1 module (AXH)
      pfam12547
      Location:371 → 415
      ATXN-1_C; Capicua transcriptional repressor modulator

    4. XM_018269508.2 → XP_018124997.1  ataxin-1

      UniProtKB/TrEMBL
      A0A1L8FSD1, A0A974CNS4, A0A974HE15
      Conserved Domains (2) summary
      pfam08517
      Location:546 → 657
      AXH; Ataxin-1 and HBP1 module (AXH)
      pfam12547
      Location:371 → 415
      ATXN-1_C; Capicua transcriptional repressor modulator

    5. XM_018269509.2 → XP_018124998.1  ataxin-1

      UniProtKB/TrEMBL
      A0A1L8FSD1, A0A974CNS4, A0A974HE15
      Conserved Domains (2) summary
      pfam08517
      Location:546 → 657
      AXH; Ataxin-1 and HBP1 module (AXH)
      pfam12547
      Location:371 → 415
      ATXN-1_C; Capicua transcriptional repressor modulator

    6. XM_041567758.1 → XP_041423692.1  ataxin-1

      UniProtKB/TrEMBL
      A0A1L8FSD1, A0A974CNS4, A0A974HE15
      Conserved Domains (2) summary
      pfam08517
      Location:546 → 657
      AXH; Ataxin-1 and HBP1 module (AXH)
      pfam12547
      Location:371 → 415
      ATXN-1_C; Capicua transcriptional repressor modulator

    7. XM_018269507.2 → XP_018124996.1  ataxin-1

      UniProtKB/TrEMBL
      A0A1L8FSD1, A0A974CNS4, A0A974HE15
      Conserved Domains (2) summary
      pfam08517
      Location:546 → 657
      AXH; Ataxin-1 and HBP1 module (AXH)
      pfam12547
      Location:371 → 415
      ATXN-1_C; Capicua transcriptional repressor modulator

    8. XM_018269506.2 → XP_018124995.1  ataxin-1

      UniProtKB/TrEMBL
      A0A1L8FSD1, A0A974CNS4, A0A974HE15
      Conserved Domains (2) summary
      pfam08517
      Location:546 → 657
      AXH; Ataxin-1 and HBP1 module (AXH)
      pfam12547
      Location:371 → 415
      ATXN-1_C; Capicua transcriptional repressor modulator

    9. XM_041567757.1 → XP_041423691.1  ataxin-1

      UniProtKB/TrEMBL
      A0A1L8FSD1, A0A974CNS4, A0A974HE15
      Conserved Domains (2) summary
      pfam08517
      Location:546 → 657
      AXH; Ataxin-1 and HBP1 module (AXH)
      pfam12547
      Location:371 → 415
      ATXN-1_C; Capicua transcriptional repressor modulator

    RNA

    1. XR_001936326.2 RNA Sequence

    2. XR_005962272.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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