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    Psmg4 proteasome assembly chaperone 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689623, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Psmg4provided by RGD
    Official Full Name
    proteasome assembly chaperone 4provided by RGD
    Primary source
    RGD:1589955
    See related
    EnsemblRapid:ENSRNOG00000039265 AllianceGenome:RGD:1589955
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305541
    Summary
    Predicted to be involved in proteasome assembly. Predicted to be part of protein-containing complex. Orthologous to human PSMG4 (proteasome assembly chaperone 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 347.3), Kidney (RPKM 334.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Psmg4 in Genome Data Viewer
    Location:
    17p12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (30916031..30923430, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (30710682..30718035, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (31402581..31411924, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene PX domain containing 1 Neighboring gene solute carrier family 22, member 23 Neighboring gene uncharacterized LOC134482704 Neighboring gene uncharacterized LOC120097753 Neighboring gene uncharacterized LOC102551220

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. 20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals. Le Tallec B, et al. Mol Cell, 2007 Aug 17. PMID 17707236
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC189533

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    proteasome assembly chaperone 4
    Names
    proteasome (prosome, macropain) assembly chaperone 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001129879.2 → NP_001123351.1  proteasome assembly chaperone 4

      See identical proteins and their annotated locations for NP_001123351.1

      Status: VALIDATED

      Source sequence(s)
      BC167096, BE113476, CN543825
      UniProtKB/TrEMBL
      B2RZB8
      Conserved Domains (1) summary
      pfam16093
      Location:28 → 95
      PAC4; Proteasome assembly chaperone 4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      30916031..30923430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039096086.2 → XP_038952014.1  proteasome assembly chaperone 4 isoform X2

      UniProtKB/TrEMBL
      A6J7G2
      Related
      ENSRNOP00000099988.1, ENSRNOT00000128394.1
      Conserved Domains (1) summary
      pfam16093
      Location:28 → 69
      PAC4; Proteasome assembly chaperone 4

    2. XM_006253847.5 → XP_006253909.1  proteasome assembly chaperone 4 isoform X1

      Conserved Domains (1) summary
      pfam16093
      Location:28 → 83
      PAC4; Proteasome assembly chaperone 4

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001109543.1: Suppressed sequence

      Description
      NM_001109543.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
    Nucleotide Protein Strain
    Heading Accession and Version

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