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    TRIM16L tripartite motif containing 16 like (pseudogene) [ Homo sapiens (human) ]

    Gene ID: 147166, updated on 10-Dec-2024

    Summary

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    Official Symbol
    TRIM16Lprovided by HGNC
    Official Full Name
    tripartite motif containing 16 like (pseudogene)provided by HGNC
    Primary source
    HGNC:HGNC:32670
    See related
    Ensembl:ENSG00000291110 AllianceGenome:HGNC:32670
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TRIM70
    Summary
    Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in esophagus (RPKM 13.7), gall bladder (RPKM 5.6) and 24 other tissues See more
    Orthologs
    all
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    Genomic context

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    See TRIM16L in Genome Data Viewer
    Location:
    17p11.2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (18697998..18736112)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (18644447..18682266)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (18601311..18639425)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:18553597-18554097 Neighboring gene PAIP1 pseudogene 2 Neighboring gene zinc finger protein 286B (pseudogene) Neighboring gene forkhead box O3B Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:18585117-18585622 Neighboring gene ubiquitin conjugating enzyme E2 S pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8279 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:18601479-18602036 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr17:18621593-18622463 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr17:18622464-18623334 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:18624898-18625462 Neighboring gene Sharpr-MPRA regulatory region 2370 Neighboring gene F-box and WD repeat domain containing 10 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr17:18673855-18674355 Neighboring gene trans-golgi network vesicle protein 23 homolog B Neighboring gene NANOG hESC enhancer GRCh37_chr17:18706781-18707432

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. TRIM59 Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer Cells by Upregulating Cell Cycle Related Proteins. Zhan W, et al. PLoS One, 2015. PMID 26599082, Free PMC Article
    2. CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system. Lim SH, et al. Mol Syst Biol, 2022 Feb. PMID 35156780, Free PMC Article
    3. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512
    4. TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing. Demirdizen E, et al. Neuro Oncol, 2023 Jun 2. PMID 36215168, Free PMC Article
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Other Names

    • tripartite motif protein 70
    • tripartite motif-containing 16-like
    • tripartite motif-containing protein 16-like protein
    • tripartite motif-containing protein 70

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_172633.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026271, AC107982

    2. NR_172634.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026271, AC107982
      Related
      ENST00000572555.5

    3. NR_172635.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026271, AC107982

    4. NR_172636.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026271
      Related
      ENST00000449697.10

    5. NR_172637.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026271, AC107982

    6. NR_172638.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC026271, AC107982

    7. NR_172639.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107982
      Related
      ENST00000571542.6

    8. NR_172640.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107982
      Related
      ENST00000424146.3

    9. NR_172641.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107982
      Related
      ENST00000641936.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      18697998..18736112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      18644447..18682266
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001037330.3: Suppressed sequence

      Description
      NM_001037330.3: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    2. NM_001353219.2: Suppressed sequence

      Description
      NM_001353219.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    3. NM_001353220.2: Suppressed sequence

      Description
      NM_001353220.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    4. NM_001353221.2: Suppressed sequence

      Description
      NM_001353221.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    5. NM_001353222.2: Suppressed sequence

      Description
      NM_001353222.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    6. NM_001353223.2: Suppressed sequence

      Description
      NM_001353223.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    7. NM_001353224.2: Suppressed sequence

      Description
      NM_001353224.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    8. NM_001353225.2: Suppressed sequence

      Description
      NM_001353225.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    9. NM_001353226.2: Suppressed sequence

      Description
      NM_001353226.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q309B1.3 GenPept UniProtKB/Swiss-Prot:Q309B1

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