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    EYA1 EYA transcriptional coactivator and phosphatase 1 [ Gallus gallus (chicken) ]

    Gene ID: 395718, updated on 3-Dec-2024

    Summary

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    Symbol
    EYA1provided by CGNC
    Full Name
    EYA transcriptional coactivator and phosphatase 1provided by CGNC
    Primary source
    CGNC:49441
    See related
    Ensembl:ENSGALG00010003210
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See EYA1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (116637896..116727240, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (116641511..116803924, complement)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene lactamase beta 2 Neighboring gene XK related 9 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC121109873

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Eya1 and Eya2 gene expression is down-regulated during somitic myogenesis in the cadmium-induced omphalocele chick model. Doi T, et al. J Pediatr Surg, 2012 Jun. PMID 22703781
    2. Multiple evolutionarily conserved enhancers control expression of Eya1. Ishihara T, et al. Dev Dyn, 2008 Nov. PMID 18816442
    3. EYA4, a novel vertebrate gene related to Drosophila eyes absent. Borsani G, et al. Hum Mol Genet, 1999 Jan. PMID 9887327
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eyes absent homolog 1
    NP_001383330.1
    NP_001383331.1
    NP_001383332.1
    NP_001383333.1
    NP_001383334.1
    XP_040518707.1
    XP_040518708.1
    XP_040518709.1
    XP_040518710.1
    XP_040518719.1
    XP_046766306.1
    XP_046766307.1
    XP_046766308.1
    XP_046766309.1
    XP_046766310.1
    XP_046766311.1
    XP_046766312.1
    XP_046766313.1
    XP_046766314.1
    XP_046766315.1
    XP_046766316.1
    XP_046766317.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396401.1 → NP_001383330.1  eyes absent homolog 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000043
      UniProtKB/TrEMBL
      A0A8V0X8Q6
      Conserved Domains (2) summary
      pfam05109
      Location:31 → 283
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:325 → 596
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

    2. NM_001396402.1 → NP_001383331.1  eyes absent homolog 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000043
      UniProtKB/TrEMBL
      A0A8V0X8Q6
      Related
      ENSGALP00010004486.1, ENSGALT00010007510.1
      Conserved Domains (2) summary
      pfam05109
      Location:31 → 283
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:325 → 596
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

    3. NM_001396403.1 → NP_001383332.1  eyes absent homolog 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000043
      UniProtKB/TrEMBL
      A0A8V0X8Q6
      Related
      ENSGALP00010004485.1, ENSGALT00010007506.1
      Conserved Domains (2) summary
      pfam05109
      Location:31 → 283
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:325 → 596
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

    4. NM_001396404.1 → NP_001383333.1  eyes absent homolog 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000043
      UniProtKB/TrEMBL
      A0A8V0X8Q6
      Related
      ENSGALP00010004481.1, ENSGALT00010007498.1
      Conserved Domains (2) summary
      pfam05109
      Location:31 → 278
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:320 → 591
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

    5. NM_001396405.1 → NP_001383334.1  eyes absent homolog 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000043
      UniProtKB/TrEMBL
      A0A8V0XIF2
      Related
      ENSGALP00010004484.1, ENSGALT00010007504.1
      Conserved Domains (2) summary
      pfam05109
      Location:38 → 254
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:296 → 541
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      116637896..116727240 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      116641511..116803924 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046910359.1 → XP_046766315.1  eyes absent homolog 1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0XIF2

    2. XM_046910358.1 → XP_046766314.1  eyes absent homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8Q6

    3. XM_046910353.1 → XP_046766309.1  eyes absent homolog 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0X8Q6

    4. XM_046910360.1 → XP_046766316.1  eyes absent homolog 1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0X8Q6

    5. XM_046910357.1 → XP_046766313.1  eyes absent homolog 1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0XIF2

    6. XM_046910351.1 → XP_046766307.1  eyes absent homolog 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0X8Q6

    7. XM_046910352.1 → XP_046766308.1  eyes absent homolog 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0X8Q6

    8. XM_046910350.1 → XP_046766306.1  eyes absent homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8Q6

    9. XM_046910361.1 → XP_046766317.1  eyes absent homolog 1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0XIF2

    10. XM_046910356.1 → XP_046766312.1  eyes absent homolog 1 isoform X7

      UniProtKB/TrEMBL
      A0A8V0X8Q6

    11. XM_046910354.1 → XP_046766310.1  eyes absent homolog 1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0X8Q6

    12. XM_046910355.1 → XP_046766311.1  eyes absent homolog 1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0X8Q1, A0A8V0X8Q6

    13. XM_040662785.2 → XP_040518719.1  eyes absent homolog 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0X8Q6
      Conserved Domains (2) summary
      pfam05109
      Location:54 → 304
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:346 → 617
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

    14. XM_040662775.2 → XP_040518709.1  eyes absent homolog 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0X8Q6
      Conserved Domains (2) summary
      pfam05109
      Location:54 → 304
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:346 → 617
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

    15. XM_040662774.2 → XP_040518708.1  eyes absent homolog 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0X8Q6
      Conserved Domains (2) summary
      pfam05109
      Location:54 → 304
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:346 → 617
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

    16. XM_040662773.2 → XP_040518707.1  eyes absent homolog 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0X8Q6
      Conserved Domains (2) summary
      pfam05109
      Location:54 → 304
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:346 → 617
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

    17. XM_040662776.2 → XP_040518710.1  eyes absent homolog 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0X8Q6
      Conserved Domains (2) summary
      pfam05109
      Location:54 → 304
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cd02601
      Location:346 → 617
      HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9YHA0.1 GenPept UniProtKB/Swiss-Prot:Q9YHA0

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