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    ATF2 activating transcription factor 2 [ Gallus gallus (chicken) ]

    Gene ID: 395727, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ATF2provided by CGNC
    Official Full Name
    activating transcription factor 2provided by CGNC
    Primary source
    CGNC:7057
    See related
    Ensembl:ENSGALG00010022485
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See ATF2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (16276963..16328708)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (16194560..16246272)

    Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112532793 Neighboring gene ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) Neighboring gene atherin-like Neighboring gene chimerin 1 Neighboring gene microRNA 1570

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcription factor ATF2 cooperates with v-Jun to promote growth factor-independent proliferation in vitro and tumor formation in vivo. Huguier S, et al. Mol Cell Biol, 1998 Dec. PMID 9819389, Free PMC Article
    2. Adiponectin decreases lipids deposition by p38 MAPK/ATF2 signaling pathway in muscle of broilers. Yan J, et al. Mol Biol Rep, 2013 Dec. PMID 24178343
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cAMP response element binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclic AMP-dependent transcription factor ATF-2
    Names
    cAMP-dependent transcription factor ATF-2
    NP_001383435.1
    NP_001383436.1
    NP_001383437.1
    NP_001383439.1
    NP_990235.1
    XP_046776990.1
    XP_046776991.1
    XP_046776992.1
    XP_046776993.1
    XP_046776994.1
    XP_046776995.1
    XP_046776996.1
    XP_046776997.1
    XP_046776998.1
    XP_046776999.1
    XP_046777000.1
    XP_046777001.1
    XP_046777002.1
    XP_046799382.1
    XP_046799383.1
    XP_046799384.1
    XP_046799385.1
    XP_046799386.1
    XP_046799387.1
    XP_046799388.1
    XP_046799389.1
    XP_046799390.1
    XP_046799391.1
    XP_046799392.1
    XP_046799393.1
    XP_046799394.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396506.1 → NP_001383435.1  cyclic AMP-dependent transcription factor ATF-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000236
      UniProtKB/TrEMBL
      A0A8V0ZIA2, A0A8V0ZNN3
      Conserved Domains (4) summary
      cd12192
      Location:47 → 84
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      cd14687
      Location:307 → 367
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
      sd00019
      Location:9 → 31
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl26244
      Location:226 → 297
      VSG_B; Trypanosomal VSG domain

    2. NM_001396507.1 → NP_001383436.1  cyclic AMP-dependent transcription factor ATF-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000236
      UniProtKB/Swiss-Prot
      O93602
      UniProtKB/TrEMBL
      A0A8V0ZNN3
      Conserved Domains (5) summary
      cd12192
      Location:47 → 84
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      PHA03247
      Location:138 → 323
      PHA03247; large tegument protein UL36; Provisional
      cd14687
      Location:336 → 396
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
      sd00019
      Location:9 → 31
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl26244
      Location:256 → 326
      VSG_B; Trypanosomal VSG domain

    3. NM_001396508.1 → NP_001383437.1  cyclic AMP-dependent transcription factor ATF-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000236
      UniProtKB/Swiss-Prot
      O93602
      UniProtKB/TrEMBL
      A0A8V0ZNN3
      Conserved Domains (5) summary
      cd12192
      Location:47 → 84
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      PHA03247
      Location:138 → 323
      PHA03247; large tegument protein UL36; Provisional
      cd14687
      Location:336 → 396
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
      sd00019
      Location:9 → 31
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl26244
      Location:256 → 326
      VSG_B; Trypanosomal VSG domain

    4. NM_001396510.1 → NP_001383439.1  cyclic AMP-dependent transcription factor ATF-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000236
      UniProtKB/Swiss-Prot
      O93602
      UniProtKB/TrEMBL
      A0A8V0ZNN3
      Conserved Domains (5) summary
      cd12192
      Location:47 → 84
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      PHA03247
      Location:138 → 323
      PHA03247; large tegument protein UL36; Provisional
      cd14687
      Location:336 → 396
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
      sd00019
      Location:9 → 31
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl26244
      Location:256 → 326
      VSG_B; Trypanosomal VSG domain

    5. NM_204904.2 → NP_990235.1  cyclic AMP-dependent transcription factor ATF-2 isoform 1

      See identical proteins and their annotated locations for NP_990235.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000236
      UniProtKB/Swiss-Prot
      O93602
      UniProtKB/TrEMBL
      A0A8V0ZNN3
      Conserved Domains (5) summary
      cd12192
      Location:47 → 84
      GCN4_cent; GCN4 central activation domain-like acidic activation domain
      PHA03247
      Location:138 → 323
      PHA03247; large tegument protein UL36; Provisional
      cd14687
      Location:336 → 396
      bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
      sd00019
      Location:9 → 31
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cl26244
      Location:256 → 326
      VSG_B; Trypanosomal VSG domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      16276963..16328708
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046943431.1 → XP_046799387.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8

    2. XM_046943430.1 → XP_046799386.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8

    3. XM_046943429.1 → XP_046799385.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8

    4. XM_046943428.1 → XP_046799384.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8

    5. XM_046943438.1 → XP_046799394.1  cyclic AMP-dependent transcription factor ATF-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZNN3

    6. XM_046943432.1 → XP_046799388.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8
      Related
      ENSGALP00010033070.1, ENSGALT00010054725.1

    7. XM_046943426.1 → XP_046799382.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

      UniProtKB/Swiss-Prot
      O93602
      UniProtKB/TrEMBL
      A0A8V0ZNN3

    8. XM_046943433.1 → XP_046799389.1  cyclic AMP-dependent transcription factor ATF-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZIA2, A0A8V0ZNN3

    9. XM_046943437.1 → XP_046799393.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZQF8, A0A8V0ZR30

    10. XM_046943427.1 → XP_046799383.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

      UniProtKB/Swiss-Prot
      O93602
      UniProtKB/TrEMBL
      A0A8V0ZNN3
      Related
      ENSGALP00010033065.1, ENSGALT00010054718.1

    11. XM_046943435.1 → XP_046799391.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZQF8, A0A8V0ZR30

    12. XM_046943434.1 → XP_046799390.1  cyclic AMP-dependent transcription factor ATF-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZIA2, A0A8V0ZNN3
      Related
      ENSGALP00010033063.1, ENSGALT00010054716.1

    13. XM_046943436.1 → XP_046799392.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZQF8, A0A8V0ZR30
      Related
      ENSGALP00010033067.1, ENSGALT00010054720.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      16194560..16246272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046921039.1 → XP_046776995.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8

    2. XM_046921038.1 → XP_046776994.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8

    3. XM_046921037.1 → XP_046776993.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8

    4. XM_046921036.1 → XP_046776992.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8

    5. XM_046921046.1 → XP_046777002.1  cyclic AMP-dependent transcription factor ATF-2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZNN3

    6. XM_046921040.1 → XP_046776996.1  cyclic AMP-dependent transcription factor ATF-2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZNN3, A0A8V0ZNN8

    7. XM_046921034.1 → XP_046776990.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

      UniProtKB/Swiss-Prot
      O93602
      UniProtKB/TrEMBL
      A0A8V0ZNN3

    8. XM_046921041.1 → XP_046776997.1  cyclic AMP-dependent transcription factor ATF-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZIA2, A0A8V0ZNN3

    9. XM_046921045.1 → XP_046777001.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZQF8, A0A8V0ZR30

    10. XM_046921035.1 → XP_046776991.1  cyclic AMP-dependent transcription factor ATF-2 isoform X1

      UniProtKB/Swiss-Prot
      O93602
      UniProtKB/TrEMBL
      A0A8V0ZNN3

    11. XM_046921043.1 → XP_046776999.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZQF8, A0A8V0ZR30

    12. XM_046921042.1 → XP_046776998.1  cyclic AMP-dependent transcription factor ATF-2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZIA2, A0A8V0ZNN3

    13. XM_046921044.1 → XP_046777000.1  cyclic AMP-dependent transcription factor ATF-2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZQF8, A0A8V0ZR30
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O93602.1 GenPept UniProtKB/Swiss-Prot:O93602

    Gene LinkOut

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