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    TXK TXK tyrosine kinase [ Equus asinus (ass) ]

    Gene ID: 106841251, updated on 13-Mar-2024

    Summary

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    Gene symbol
    TXK
    Gene description
    TXK tyrosine kinase
    See related
    Ensembl:ENSEASG00005008912
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus asinus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See TXK in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    101 current ASM1607732v2 (GCF_016077325.2) 3 NC_052179.1 (136735254..136795796, complement)
    100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014638148.1 (531874..596459)

    Chromosome 3 - NC_052179.1Genomic Context describing neighboring genes Neighboring gene glutathione peroxidase 1-like Neighboring gene NIPA like domain containing 1 Neighboring gene tec protein tyrosine kinase Neighboring gene SLAIN motif family member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in T cell receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adaptive immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-tyrosine autophosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of platelet activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tissue regeneration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase TXK

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1607732v2

    Genomic

    1. NC_052179.1 Reference ASM1607732v2

      Range
      136735254..136795796 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014857122.2 → XP_014712608.1  tyrosine-protein kinase TXK isoform X2

      UniProtKB/TrEMBL
      A0A8C4LLE3
      Related
      ENSEASP00005012777.2, ENSEAST00005013886.2
      Conserved Domains (4) summary
      cd05059
      Location:290 → 545
      PTKc_Tec_like; Catalytic domain of Tec-like Protein Tyrosine Kinases
      cd10398
      Location:167 → 272
      SH2_Tec_Txk; Src homology 2 (SH2) domain found in Tec protein, Txk
      cd11907
      Location:109 → 163
      SH3_TXK; Src Homology 3 domain of TXK, also called Resting lymphocyte kinase (Rlk)
      pfam07714
      Location:295 → 544
      Pkinase_Tyr; Protein tyrosine kinase

    2. XM_044765926.1 → XP_044621861.1  tyrosine-protein kinase TXK isoform X3

      UniProtKB/TrEMBL
      A0A8C4LNM2
      Related
      ENSEASP00005012776.2, ENSEAST00005013884.2
      Conserved Domains (3) summary
      cd05059
      Location:276 → 531
      PTKc_Tec_like; Catalytic domain of Tec-like Protein Tyrosine Kinases
      cd10398
      Location:153 → 258
      SH2_Tec_Txk; Src homology 2 (SH2) domain found in Tec protein, Txk
      cd11907
      Location:95 → 149
      SH3_TXK; Src Homology 3 domain of TXK, also called Resting lymphocyte kinase (Rlk)

    3. XM_014857123.2 → XP_014712609.1  tyrosine-protein kinase TXK isoform X3

      UniProtKB/TrEMBL
      A0A8C4LNM2
      Conserved Domains (3) summary
      cd05059
      Location:276 → 531
      PTKc_Tec_like; Catalytic domain of Tec-like Protein Tyrosine Kinases
      cd10398
      Location:153 → 258
      SH2_Tec_Txk; Src homology 2 (SH2) domain found in Tec protein, Txk
      cd11907
      Location:95 → 149
      SH3_TXK; Src Homology 3 domain of TXK, also called Resting lymphocyte kinase (Rlk)

    4. XM_044765927.1 → XP_044621862.1  tyrosine-protein kinase TXK isoform X5

      Conserved Domains (3) summary
      cd05059
      Location:219 → 474
      PTKc_Tec_like; Catalytic domain of Tec-like Protein Tyrosine Kinases
      cd10398
      Location:96 → 201
      SH2_Tec_Txk; Src homology 2 (SH2) domain found in Tec protein, Txk
      cd11907
      Location:38 → 92
      SH3_TXK; Src Homology 3 domain of TXK, also called Resting lymphocyte kinase (Rlk)

    5. XM_044765925.1 → XP_044621860.1  tyrosine-protein kinase TXK isoform X1

      UniProtKB/TrEMBL
      A0A8C4LJE4
      Related
      ENSEASP00005012778.2, ENSEAST00005013887.2
      Conserved Domains (3) summary
      cd05059
      Location:306 → 561
      PTKc_Tec_like; Catalytic domain of Tec-like Protein Tyrosine Kinases
      cd10398
      Location:183 → 288
      SH2_Tec_Txk; Src homology 2 (SH2) domain found in Tec protein, Txk
      cd11907
      Location:125 → 179
      SH3_TXK; Src Homology 3 domain of TXK, also called Resting lymphocyte kinase (Rlk)

    6. XM_014857126.2 → XP_014712612.1  tyrosine-protein kinase TXK isoform X4

      Conserved Domains (4) summary
      cd05059
      Location:266 → 521
      PTKc_Tec_like; Catalytic domain of Tec-like Protein Tyrosine Kinases
      cd10398
      Location:143 → 248
      SH2_Tec_Txk; Src homology 2 (SH2) domain found in Tec protein, Txk
      cd11907
      Location:85 → 139
      SH3_TXK; Src Homology 3 domain of TXK, also called Resting lymphocyte kinase (Rlk)
      pfam07714
      Location:271 → 520
      Pkinase_Tyr; Protein tyrosine kinase
    Nucleotide Protein
    Heading Accession and Version

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