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    FOXP2 forkhead box P2 [ Gallus gallus (chicken) ]

    Gene ID: 769935, updated on 3-Dec-2024

    Summary

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    Official Symbol
    FOXP2provided by CGNC
    Official Full Name
    forkhead box P2provided by CGNC
    Primary source
    CGNC:7164
    See related
    Ensembl:ENSGALG00010001407
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See FOXP2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (26060300..26472682, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (26321021..26733835, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112533188 Neighboring gene MyoD family inhibitor domain containing Neighboring gene uncharacterized LOC121109003 Neighboring gene uncharacterized LOC112533189 Neighboring gene uncharacterized LOC121109004 Neighboring gene protein phosphatase 1 regulatory subunit 3A Neighboring gene uncharacterized LOC121107432

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FoxP2 protein decreases at a specific region in the chick midbrain after hatching. Bessho C, et al. Neurosci Lett, 2023 Mar 13. PMID 36773927
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FoxP2 protein decreases at a specific region in the chick midbrain after hatching.
      Title: FoxP2 protein decreases at a specific region in the chick midbrain after hatching.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    forkhead box protein P2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001397265.1 → NP_001384194.1  forkhead box protein P2 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      A0A8V0X8C6, G8HZH9
      Related
      ENSGALP00010001718.1, ENSGALT00010003262.1
      Conserved Domains (3) summary
      COG5025
      Location:470 → 701
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:335 → 402
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:496 → 577
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    2. NM_001397266.1 → NP_001384195.1  forkhead box protein P2 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      A0A8V0XB47, G8HZH8
      Related
      ENSGALP00010001722.1, ENSGALT00010003265.1
      Conserved Domains (3) summary
      COG5025
      Location:469 → 700
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:334 → 401
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:495 → 576
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    3. NM_001397267.1 → NP_001384196.1  forkhead box protein P2 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      A0A8V0XB47, G8HZH8
      Conserved Domains (3) summary
      COG5025
      Location:469 → 700
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:334 → 401
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:495 → 576
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    4. NM_001397268.1 → NP_001384197.1  forkhead box protein P2 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      A0A8V0XB47, G8HZH8
      Conserved Domains (3) summary
      COG5025
      Location:469 → 700
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:334 → 401
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:495 → 576
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    5. NM_001397269.1 → NP_001384198.1  forkhead box protein P2 isoform c

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      G8HZI1
      Related
      ENSGALP00010001716.1, ENSGALT00010003259.1
      Conserved Domains (3) summary
      COG5025
      Location:450 → 681
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:315 → 382
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:476 → 557
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    6. NM_001397270.1 → NP_001384199.1  forkhead box protein P2 isoform c

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      G8HZI1
      Conserved Domains (3) summary
      COG5025
      Location:450 → 681
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:315 → 382
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:476 → 557
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    7. NM_001397271.1 → NP_001384200.1  forkhead box protein P2 isoform d

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      A0A8V0XB05, G8HZI0
      Related
      ENSGALP00010001704.1, ENSGALT00010003247.1
      Conserved Domains (2) summary
      smart00339
      Location:476 → 548
      FH; FORKHEAD
      COG5025
      Location:449 → 680
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]

    8. NM_001397272.1 → NP_001384201.1  forkhead box protein P2 isoform e

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      G8HZH9
      Conserved Domains (3) summary
      COG5025
      Location:440 → 671
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:305 → 372
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:466 → 547
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    9. NM_001397273.1 → NP_001384202.1  forkhead box protein P2 isoform f

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000012
      UniProtKB/TrEMBL
      G8HZH8
      Conserved Domains (2) summary
      smart00339
      Location:466 → 538
      FH; FORKHEAD
      COG5025
      Location:439 → 670
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      26060300..26472682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025151566.3 → XP_025007334.1  forkhead box protein P2 isoform X7

      UniProtKB/TrEMBL
      G8HZH9
      Conserved Domains (2) summary
      cd00059
      Location:405 → 477
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:243 → 310
      FOXP-CC; FOXP coiled-coil domain

    2. XM_025151568.3 → XP_025007336.1  forkhead box protein P2 isoform X7

      UniProtKB/TrEMBL
      G8HZH9
      Conserved Domains (2) summary
      cd00059
      Location:405 → 477
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:243 → 310
      FOXP-CC; FOXP coiled-coil domain

    3. XM_025151569.3 → XP_025007337.1  forkhead box protein P2 isoform X9

      UniProtKB/TrEMBL
      G8HZH9
      Conserved Domains (2) summary
      cd00059
      Location:514 → 586
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:352 → 419
      FOXP-CC; FOXP coiled-coil domain

    4. XM_040701928.2 → XP_040557862.1  forkhead box protein P2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8C6, G8HZH9
      Conserved Domains (3) summary
      COG5025
      Location:470 → 701
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:335 → 402
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:496 → 577
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    5. XM_025151551.3 → XP_025007319.1  forkhead box protein P2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8C6, G8HZH9
      Conserved Domains (3) summary
      COG5025
      Location:470 → 701
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:335 → 402
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:496 → 577
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    6. XM_046943292.1 → XP_046799248.1  forkhead box protein P2 isoform X5

      UniProtKB/TrEMBL
      G8HZH8

    7. XM_040701976.2 → XP_040557910.1  forkhead box protein P2 isoform X4

      UniProtKB/TrEMBL
      G8HZH9
      Conserved Domains (3) summary
      COG5025
      Location:440 → 671
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:305 → 372
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:466 → 547
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    8. XM_025151542.3 → XP_025007310.1  forkhead box protein P2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8C6, G8HZH9
      Conserved Domains (3) summary
      COG5025
      Location:470 → 701
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:335 → 402
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:496 → 577
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    9. XM_046943289.1 → XP_046799245.1  forkhead box protein P2 isoform X3

      UniProtKB/TrEMBL
      G8HZI1

    10. XM_040701954.2 → XP_040557888.1  forkhead box protein P2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XB47, G8HZH8
      Conserved Domains (3) summary
      COG5025
      Location:469 → 700
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:334 → 401
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:495 → 576
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    11. XM_040701946.2 → XP_040557880.1  forkhead box protein P2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8C6, G8HZH9
      Conserved Domains (3) summary
      COG5025
      Location:470 → 701
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam16159
      Location:335 → 402
      FOXP-CC; FOXP coiled-coil domain
      cd20065
      Location:496 → 577
      FH_FOXP2; Forkhead (FH) domain found in Forkhead box protein P2 (FOXP2)

    12. XM_040701983.1 → XP_040557917.1  forkhead box protein P2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0X8B7, G8HZI1
      Related
      ENSGALP00010001708.1, ENSGALT00010003251.1
      Conserved Domains (2) summary
      smart00339
      Location:447 → 519
      FH; FORKHEAD
      COG5025
      Location:420 → 651
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]

    13. XM_040701995.2 → XP_040557929.1  forkhead box protein P2 isoform X8

      UniProtKB/TrEMBL
      G8HZH9
      Conserved Domains (1) summary
      smart00339
      Location:497 → 569
      FH; FORKHEAD

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      26321021..26733835 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046908639.1 → XP_046764595.1  forkhead box protein P2 isoform X7

      UniProtKB/TrEMBL
      G8HZH9

    2. XM_046908640.1 → XP_046764596.1  forkhead box protein P2 isoform X7

      UniProtKB/TrEMBL
      G8HZH9

    3. XM_046908642.1 → XP_046764598.1  forkhead box protein P2 isoform X9

      UniProtKB/TrEMBL
      G8HZH9

    4. XM_046908630.1 → XP_046764586.1  forkhead box protein P2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8C6, G8HZH9

    5. XM_046908633.1 → XP_046764589.1  forkhead box protein P2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8C6, G8HZH9

    6. XM_046908637.1 → XP_046764593.1  forkhead box protein P2 isoform X5

      UniProtKB/TrEMBL
      G8HZH8

    7. XM_046908636.1 → XP_046764592.1  forkhead box protein P2 isoform X4

      UniProtKB/TrEMBL
      G8HZH9

    8. XM_046908632.1 → XP_046764588.1  forkhead box protein P2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8C6, G8HZH9

    9. XM_046908635.1 → XP_046764591.1  forkhead box protein P2 isoform X3

      UniProtKB/TrEMBL
      G8HZI1

    10. XM_046908634.1 → XP_046764590.1  forkhead box protein P2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XB47, G8HZH8

    11. XM_046908631.1 → XP_046764587.1  forkhead box protein P2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X8C6, G8HZH9

    12. XM_046908638.1 → XP_046764594.1  forkhead box protein P2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0X8B7, G8HZI1

    13. XM_046908641.1 → XP_046764597.1  forkhead box protein P2 isoform X8

      UniProtKB/TrEMBL
      G8HZH9

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001318413.1: Suppressed sequence

      Description
      NM_001318413.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version

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