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    MTMR3 myotubularin related protein 3 [ Gallus gallus (chicken) ]

    Gene ID: 417015, updated on 3-Dec-2024

    Summary

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    Official Symbol
    MTMR3provided by CGNC
    Official Full Name
    myotubularin related protein 3provided by CGNC
    Primary source
    CGNC:6094
    See related
    Ensembl:ENSGALG00010000263
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See MTMR3 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (10928494..11002933, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (10940269..11014688, complement)

    Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene HORMA domain containing 2 Neighboring gene putative acyl-CoA dehydrogenase AidB-like Neighboring gene activating signal cointegrator 1 complex subunit 2 Neighboring gene ubiquinol-cytochrome c reductase, complex III subunit X

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3-phosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein phosphatase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3; myotubularin-related protein 3
    NP_001292595.2
    NP_001384455.1
    XP_015150329.2
    XP_040504017.1
    XP_040504021.1
    XP_040504022.1
    XP_040504023.1
    XP_040504024.1
    XP_046757122.1
    XP_046757123.1
    XP_046757124.1
    XP_046757125.1
    XP_046757126.1
    XP_046757127.1
    XP_046757128.1
    XP_046757129.1
    XP_046757130.1
    XP_046757131.1
    XP_046757132.1
    XP_046784169.1
    XP_046784170.1
    XP_046784172.1
    XP_046784173.1
    XP_046784174.1
    XP_046784175.1
    XP_046784176.1
    XP_046784177.1
    XP_046784178.1
    XP_046784179.1
    XP_046784180.1
    XP_046784181.1
    XP_046784182.1
    XP_046784183.1
    XP_046784184.1
    XP_046784185.1
    XP_046784186.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305666.2 → NP_001292595.2  phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000260
      UniProtKB/TrEMBL
      A0A8V0X4W3, A0A8V0X6S7
      Related
      ENSGALP00010000286.1, ENSGALT00010000513.1

    2. NM_001397526.1 → NP_001384455.1  phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000260
      UniProtKB/TrEMBL
      A0A8V0X4W3, A0A8V0X6S7
      Related
      ENSGALP00010000290.1, ENSGALT00010000517.1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      10928494..11002933 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040648090.2 → XP_040504024.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3
      Conserved Domains (3) summary
      cd15732
      Location:1125 → 1194
      FYVE_MTMR3; FYVE domain found in myotubularin-related protein 3 (MTMR3) and similar proteins
      cd14586
      Location:180 → 496
      PTP-MTMR3; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 3
      cl17171
      Location:23 → 147
      PH-like; Pleckstrin homology-like domain

    2. XM_040648088.2 → XP_040504022.1  myotubularin-related protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8V0X4W3
      Conserved Domains (3) summary
      cd15732
      Location:1176 → 1245
      FYVE_MTMR3; FYVE domain found in myotubularin-related protein 3 (MTMR3) and similar proteins
      cd14586
      Location:231 → 547
      PTP-MTMR3; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 3
      cl17171
      Location:74 → 198
      PH-like; Pleckstrin homology-like domain

    3. XM_046901172.1 → XP_046757128.1  myotubularin-related protein 3 isoform X8

      UniProtKB/TrEMBL
      A0A8V0X2L8, A0A8V0X4W3
      Related
      ENSGALP00010000287.1, ENSGALT00010000514.1

    4. XM_046901171.1 → XP_046757127.1  myotubularin-related protein 3 isoform X7

      UniProtKB/TrEMBL
      A0A8V0X4W3, A0A8V0X754
      Related
      ENSGALP00010000289.1, ENSGALT00010000516.1

    5. XM_046901169.1 → XP_046757125.1  myotubularin-related protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A8V0X4W3, A0A8V0X6S7

    6. XM_046901168.1 → XP_046757124.1  myotubularin-related protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8V0X4W3, A0A8V0X749
      Related
      ENSGALP00010000284.1, ENSGALT00010000511.1

    7. XM_046901170.1 → XP_046757126.1  myotubularin-related protein 3 isoform X6

      UniProtKB/TrEMBL
      A0A8V0X4W3

    8. XM_040648083.2 → XP_040504017.1  myotubularin-related protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A8V0X4W3
      Conserved Domains (3) summary
      cd15732
      Location:1088 → 1157
      FYVE_MTMR3; FYVE domain found in myotubularin-related protein 3 (MTMR3) and similar proteins
      cd14586
      Location:180 → 496
      PTP-MTMR3; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 3
      cl17171
      Location:23 → 147
      PH-like; Pleckstrin homology-like domain

    9. XM_046901167.1 → XP_046757123.1  myotubularin-related protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A8V0X4W3

    10. XM_046901166.1 → XP_046757122.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3

    11. XM_040648089.2 → XP_040504023.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3
      Conserved Domains (3) summary
      cd15732
      Location:1125 → 1194
      FYVE_MTMR3; FYVE domain found in myotubularin-related protein 3 (MTMR3) and similar proteins
      cd14586
      Location:180 → 496
      PTP-MTMR3; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 3
      cl17171
      Location:23 → 147
      PH-like; Pleckstrin homology-like domain

    12. XM_040648087.2 → XP_040504021.1  myotubularin-related protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8V0X4W3
      Conserved Domains (3) summary
      cd15732
      Location:1176 → 1245
      FYVE_MTMR3; FYVE domain found in myotubularin-related protein 3 (MTMR3) and similar proteins
      cd14586
      Location:231 → 547
      PTP-MTMR3; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 3
      cl17171
      Location:74 → 198
      PH-like; Pleckstrin homology-like domain

    13. XM_046901176.1 → XP_046757132.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3

    14. XM_046901174.1 → XP_046757130.1  myotubularin-related protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8V0X4W3

    15. XM_046901175.1 → XP_046757131.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3

    16. XM_046901173.1 → XP_046757129.1  myotubularin-related protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8V0X4W3

    17. XM_015294843.4 → XP_015150329.2  myotubularin-related protein 3 isoform X10

      Conserved Domains (2) summary
      cd15732
      Location:920 → 989
      FYVE_MTMR3; FYVE domain found in myotubularin-related protein 3 (MTMR3) and similar proteins
      cl28904
      Location:30 → 291
      PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      10940269..11014688 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046928227.1 → XP_046784183.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3

    2. XM_046928225.1 → XP_046784181.1  myotubularin-related protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8V0X4W3

    3. XM_046928221.1 → XP_046784177.1  myotubularin-related protein 3 isoform X8

      UniProtKB/TrEMBL
      A0A8V0X4W3

    4. XM_046928220.1 → XP_046784176.1  myotubularin-related protein 3 isoform X7

      UniProtKB/TrEMBL
      A0A8V0X4W3

    5. XM_046928217.1 → XP_046784173.1  myotubularin-related protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A8V0X4W3

    6. XM_046928216.1 → XP_046784172.1  myotubularin-related protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A8V0X4W3

    7. XM_046928219.1 → XP_046784175.1  myotubularin-related protein 3 isoform X6

      UniProtKB/TrEMBL
      A0A8V0X4W3

    8. XM_046928218.1 → XP_046784174.1  myotubularin-related protein 3 isoform X5

      UniProtKB/TrEMBL
      A0A8V0X4W3

    9. XM_046928214.1 → XP_046784170.1  myotubularin-related protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A8V0X4W3

    10. XM_046928213.1 → XP_046784169.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3

    11. XM_046928226.1 → XP_046784182.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3

    12. XM_046928222.1 → XP_046784178.1  myotubularin-related protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8V0X4W3

    13. XM_046928229.1 → XP_046784185.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3

    14. XM_046928224.1 → XP_046784180.1  myotubularin-related protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8V0X4W3

    15. XM_046928228.1 → XP_046784184.1  myotubularin-related protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8V0X4W3

    16. XM_046928223.1 → XP_046784179.1  myotubularin-related protein 3 isoform X9

      UniProtKB/TrEMBL
      A0A8V0X4W3

    17. XM_046928230.1 → XP_046784186.1  myotubularin-related protein 3 isoform X10

    Nucleotide Protein Strain
    Heading Accession and Version

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