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    MPP6 membrane palmitoylated protein 6 [ Gallus gallus (chicken) ]

    Gene ID: 420622, updated on 3-Dec-2024

    Summary

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    Symbol
    MPP6provided by CGNC
    Full Name
    membrane palmitoylated protein 6provided by CGNC
    Primary source
    CGNC:8351
    See related
    Ensembl:ENSGALG00010002385
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See MPP6 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (31451224..31508769)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (31496544..31554084)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110125 Neighboring gene neuropeptide Y Neighboring gene DFNA5, deafness associated tumor suppressor Neighboring gene oxysterol binding protein like 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    MAGUK p55 subfamily member 6; protein PALS2
    Names
    membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      31451224..31508769
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046937925.1 → XP_046793881.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    2. XM_046937926.1 → XP_046793882.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    3. XM_046937927.1 → XP_046793883.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    4. XM_046937923.1 → XP_046793879.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Related
      ENSGALP00010003309.1, ENSGALT00010005470.1

    5. XM_046937924.1 → XP_046793880.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    6. XM_040696613.1 → XP_040552547.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Conserved Domains (5) summary
      smart00569
      Location:2 → 55
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12038
      Location:219 → 279
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:133 → 206
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:337 → 527
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:57 → 108
      L27; L27 domain

    7. XM_046937929.1 → XP_046793885.1  protein PALS2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XG33

    8. XM_046937922.1 → XP_046793878.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    9. XM_015281841.4 → XP_015137327.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Related
      ENSGALP00010003313.1, ENSGALT00010005474.1
      Conserved Domains (5) summary
      smart00569
      Location:2 → 55
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12038
      Location:219 → 279
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:133 → 206
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:337 → 527
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:57 → 108
      L27; L27 domain

    10. XM_040696618.2 → XP_040552552.1  protein PALS2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XG33
      Conserved Domains (4) summary
      cd12038
      Location:213 → 273
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:127 → 200
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:331 → 521
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:51 → 102
      L27; L27 domain

    11. XM_015281842.4 → XP_015137328.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Related
      ENSGALP00010003311.1, ENSGALT00010005472.1
      Conserved Domains (5) summary
      smart00569
      Location:2 → 55
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12038
      Location:219 → 279
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:133 → 206
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:337 → 527
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:57 → 108
      L27; L27 domain

    12. XM_025147432.3 → XP_025003200.1  protein PALS2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XG33
      Related
      ENSGALP00010003306.1, ENSGALT00010005467.1
      Conserved Domains (4) summary
      cd12038
      Location:213 → 273
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:127 → 200
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:331 → 521
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:51 → 102
      L27; L27 domain

    13. XM_046937928.1 → XP_046793884.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    14. XM_025147429.2 → XP_025003197.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Related
      ENSGALP00010003307.1, ENSGALT00010005468.1
      Conserved Domains (5) summary
      smart00569
      Location:2 → 55
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12038
      Location:219 → 279
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:133 → 206
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:337 → 527
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:57 → 108
      L27; L27 domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      31496544..31554084
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046912367.1 → XP_046768323.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    2. XM_046912366.1 → XP_046768322.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    3. XM_046912368.1 → XP_046768324.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    4. XM_046912364.1 → XP_046768320.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    5. XM_046912365.1 → XP_046768321.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    6. XM_040665987.1 → XP_040521921.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Conserved Domains (5) summary
      smart00569
      Location:2 → 55
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12038
      Location:219 → 279
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:133 → 206
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:337 → 527
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:57 → 108
      L27; L27 domain

    7. XM_046912370.1 → XP_046768326.1  protein PALS2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XG33

    8. XM_046912363.1 → XP_046768319.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    9. XM_040665986.2 → XP_040521920.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Conserved Domains (5) summary
      smart00569
      Location:2 → 55
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12038
      Location:219 → 279
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:133 → 206
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:337 → 527
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:57 → 108
      L27; L27 domain

    10. XM_046912371.1 → XP_046768327.1  protein PALS2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XG33

    11. XM_046912362.1 → XP_046768318.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    12. XM_040665984.2 → XP_040521918.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Conserved Domains (5) summary
      smart00569
      Location:2 → 55
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12038
      Location:219 → 279
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:133 → 206
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:337 → 527
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:57 → 108
      L27; L27 domain

    13. XM_040665993.2 → XP_040521927.1  protein PALS2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XG33
      Conserved Domains (4) summary
      cd12038
      Location:213 → 273
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:127 → 200
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:331 → 521
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:51 → 102
      L27; L27 domain

    14. XM_040665985.2 → XP_040521919.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Conserved Domains (5) summary
      smart00569
      Location:2 → 55
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12038
      Location:219 → 279
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:133 → 206
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:337 → 527
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:57 → 108
      L27; L27 domain

    15. XM_040665994.2 → XP_040521928.1  protein PALS2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XG33
      Conserved Domains (4) summary
      cd12038
      Location:213 → 273
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:127 → 200
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:331 → 521
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:51 → 102
      L27; L27 domain

    16. XM_046912369.1 → XP_046768325.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33

    17. XM_040665992.1 → XP_040521926.1  protein PALS2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XCJ9, A0A8V0XG33
      Conserved Domains (5) summary
      smart00569
      Location:2 → 55
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12038
      Location:219 → 279
      SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
      cd00992
      Location:133 → 206
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:337 → 527
      Guanylate_kin; Guanylate kinase
      pfam02828
      Location:57 → 108
      L27; L27 domain
    Nucleotide Protein Strain
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