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    SLC12A2 solute carrier family 12 member 2 [ Gallus gallus (chicken) ]

    Gene ID: 427123, updated on 3-Dec-2024

    Summary

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    Symbol
    SLC12A2provided by CGNC
    Full Name
    solute carrier family 12 member 2provided by CGNC
    Primary source
    CGNC:10891
    See related
    Ensembl:ENSGALG00010012969
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See SLC12A2 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (57500796..57555527)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (57500796..57555527)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107052357 Neighboring gene uncharacterized LOC112530573 Neighboring gene uncharacterized LOC121108261 Neighboring gene fibrillin 2 Neighboring gene uncharacterized LOC121108262

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tags. Hubbard SJ, et al. Genome Res, 2005 Jan. PMID 15590942, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ammonium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sodium:potassium:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell volume homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    solute carrier family 12 member 2
    Names
    solute carrier family 12 (sodium/potassium/chloride transporter), member 2
    solute carrier family 12 (sodium/potassium/chloride transporters), member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      57500796..57555527
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003643059.6 → XP_003643107.1  solute carrier family 12 member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YJV8, F1NR57
      Related
      ENSGALP00010018118.1, ENSGALT00010031124.1
      Conserved Domains (4) summary
      TIGR00930
      Location:150 → 1150
      2a30; K-Cl cotransporter
      pfam03522
      Location:734 → 1150
      SLC12; Solute carrier family 12
      pfam08403
      Location:136 → 197
      AA_permease_N; Amino acid permease N-terminal
      cl00456
      Location:242 → 676
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. XM_004949378.5 → XP_004949435.1  solute carrier family 12 member 2 isoform X3

      UniProtKB/TrEMBL
      A0A1D5PPU2, A0A8V0YJV8
      Related
      ENSGALP00010018114.1, ENSGALT00010031120.1
      Conserved Domains (4) summary
      TIGR00930
      Location:150 → 1134
      2a30; K-Cl cotransporter
      pfam03522
      Location:734 → 1134
      SLC12; Solute carrier family 12
      pfam08403
      Location:136 → 197
      AA_permease_N; Amino acid permease N-terminal
      cl00456
      Location:242 → 676
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    3. XM_004949377.5 → XP_004949434.1  solute carrier family 12 member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YJV8
      Conserved Domains (4) summary
      TIGR00930
      Location:150 → 1149
      2a30; K-Cl cotransporter
      pfam03522
      Location:734 → 1149
      SLC12; Solute carrier family 12
      pfam08403
      Location:136 → 197
      AA_permease_N; Amino acid permease N-terminal
      cl00456
      Location:242 → 676
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    4. XM_040655729.2 → XP_040511663.1  solute carrier family 12 member 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YJV8
      Conserved Domains (1) summary
      TIGR00930
      Location:150 → 1133
      2a30; K-Cl cotransporter

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      57500796..57555527
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046936914.1 → XP_046792870.1  solute carrier family 12 member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YJV8, F1NR57

    2. XM_046936916.1 → XP_046792872.1  solute carrier family 12 member 2 isoform X3

      UniProtKB/TrEMBL
      A0A1D5PPU2, A0A8V0YJV8

    3. XM_046936915.1 → XP_046792871.1  solute carrier family 12 member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YJV8

    4. XM_046936917.1 → XP_046792873.1  solute carrier family 12 member 2 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YJV8
    Nucleotide Protein
    Heading Accession and Version

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