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    CDK8 cyclin dependent kinase 8 [ Gallus gallus (chicken) ]

    Gene ID: 428080, updated on 17-Aug-2024

    Summary

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    Symbol
    CDK8provided by CGNC
    Full Name
    cyclin dependent kinase 8provided by CGNC
    Primary source
    CGNC:12849
    See related
    Ensembl:ENSGALG00010005875
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See CDK8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (176459722..176528846, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (176539812..176614020, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 12 Neighboring gene WASP family member 3 Neighboring gene ring finger protein 6 Neighboring gene ATPase phospholipid transporting 8A2 Neighboring gene uncharacterized LOC121113404

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 8
    XP_004938840.2
    XP_015134480.1
    XP_025002615.1
    XP_040514364.1
    XP_040514365.1
    XP_040514366.1
    XP_040514367.1
    XP_040514368.1
    XP_040560121.1
    XP_046765183.1
    XP_046770403.1
    XP_425638.4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      176459722..176528846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015278994.4 → XP_015134480.1  cyclin-dependent kinase 8 isoform X4

      UniProtKB/TrEMBL
      E1C2T0
      Conserved Domains (1) summary
      cl21453
      Location:1 → 275
      PKc_like; Protein Kinases, catalytic domain

    2. XM_046914447.1 → XP_046770403.1  cyclin-dependent kinase 8 isoform X3

    3. XM_004938783.5 → XP_004938840.2  cyclin-dependent kinase 8 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XNJ2
      Related
      ENSGALP00010008272.1, ENSGALT00010014045.1
      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    4. XM_425638.8 → XP_425638.4  cyclin-dependent kinase 8 isoform X1

      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    5. XM_025146847.2 → XP_025002615.1  cyclin-dependent kinase 8 isoform X5

      Conserved Domains (1) summary
      cl21453
      Location:1 → 162
      PKc_like; Protein Kinases, catalytic domain

    6. XM_040704187.2 → XP_040560121.1  cyclin-dependent kinase 8 isoform X6

      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      176539812..176614020 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040658432.2 → XP_040514366.1  cyclin-dependent kinase 8 isoform X7

      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    2. XM_040658433.2 → XP_040514367.1  cyclin-dependent kinase 8 isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1 → 275
      PKc_like; Protein Kinases, catalytic domain

    3. XM_046909227.1 → XP_046765183.1  cyclin-dependent kinase 8 isoform X3

    4. XM_040658431.2 → XP_040514365.1  cyclin-dependent kinase 8 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XNJ2
      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    5. XM_040658430.2 → XP_040514364.1  cyclin-dependent kinase 8 isoform X1

      Conserved Domains (1) summary
      cd07868
      Location:3 → 335
      STKc_CDK8; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 8

    6. XM_040658434.1 → XP_040514368.1  cyclin-dependent kinase 8 isoform X5

      Conserved Domains (1) summary
      cl21453
      Location:1 → 162
      PKc_like; Protein Kinases, catalytic domain

    RNA

    1. XR_005844076.2 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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