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    USP33 ubiquitin specific peptidase 33 [ Gallus gallus (chicken) ]

    Gene ID: 424553, updated on 3-Dec-2024

    Summary

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    Symbol
    USP33provided by CGNC
    Full Name
    ubiquitin specific peptidase 33provided by CGNC
    Primary source
    CGNC:6817
    See related
    Ensembl:ENSGALG00010022345
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See USP33 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (18669317..18704146)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (18677019..18711834)

    Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene GIPC PDZ domain containing family member 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member B4 Neighboring gene far upstream element binding protein 1 Neighboring gene nexilin F-actin binding protein Neighboring gene mitoguardin 1 Neighboring gene uncharacterized LOC121113433 Neighboring gene zinc finger ZZ-type containing 3 Neighboring gene adenylate kinase 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 33
    XP_004936727.1
    XP_004936728.1
    XP_004936729.1
    XP_004936730.1
    XP_015146379.1
    XP_015146380.1
    XP_040534218.1
    XP_040534219.1
    XP_040534220.1
    XP_040534221.1
    XP_040534222.1
    XP_040534223.1
    XP_040534224.1
    XP_040534225.1
    XP_040534227.1
    XP_040561240.1
    XP_040561241.1
    XP_046779012.1
    XP_046779013.1
    XP_046800742.1
    XP_046800743.1
    XP_422389.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      18669317..18704146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004936670.5 → XP_004936727.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:859 → 940
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:54 → 426
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:200 → 731
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:78 → 138
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:751 → 833
      DUSP; DUSP domain

    2. XM_004936671.5 → XP_004936728.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:856 → 937
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:54 → 426
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:200 → 728
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:78 → 138
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:748 → 830
      DUSP; DUSP domain

    3. XM_004936672.5 → XP_004936729.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Related
      ENSGALP00010032838.1, ENSGALT00010054364.1
      Conserved Domains (5) summary
      smart00695
      Location:848 → 929
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:54 → 426
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:200 → 720
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:78 → 138
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:740 → 822
      DUSP; DUSP domain

    4. XM_422389.7 → XP_422389.3  ubiquitin carboxyl-terminal hydrolase 33 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:811 → 892
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:6 → 378
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:152 → 683
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:30 → 90
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:703 → 785
      DUSP; DUSP domain

    5. XM_040705306.2 → XP_040561240.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00290
      Location:29 → 81
      ZnF_UBP; Ubiquitin Carboxyl-terminal Hydrolase-like zinc finger
      smart00695
      Location:808 → 889
      DUSP; Domain in ubiquitin-specific proteases
      COG5560
      Location:147 → 684
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:441 → 681
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl12116
      Location:700 → 782
      DUSP; DUSP domain

    6. XM_040705307.2 → XP_040561241.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00290
      Location:29 → 81
      ZnF_UBP; Ubiquitin Carboxyl-terminal Hydrolase-like zinc finger
      smart00695
      Location:800 → 881
      DUSP; Domain in ubiquitin-specific proteases
      COG5560
      Location:147 → 676
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:441 → 673
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl12116
      Location:692 → 774
      DUSP; DUSP domain

    7. XM_046944786.1 → XP_046800742.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZHN6

    8. XM_046944787.1 → XP_046800743.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Related
      ENSGALP00010032835.1, ENSGALT00010054358.1

    9. XM_015290893.3 → XP_015146379.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:811 → 892
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:6 → 378
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:152 → 683
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:30 → 90
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:703 → 785
      DUSP; DUSP domain

    10. XM_015290894.3 → XP_015146380.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:811 → 892
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:6 → 378
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:152 → 683
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:30 → 90
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:703 → 785
      DUSP; DUSP domain

    11. XM_004936673.5 → XP_004936730.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X7

      UniProtKB/TrEMBL
      A0A8V0ZQA6
      Related
      ENSGALP00010032844.1, ENSGALT00010054372.1
      Conserved Domains (5) summary
      smart00695
      Location:767 → 848
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:4 → 334
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:108 → 639
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:4 → 46
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:659 → 741
      DUSP; DUSP domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      18677019..18711834
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040678284.2 → XP_040534218.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:859 → 940
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:54 → 426
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:200 → 731
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:78 → 138
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:751 → 833
      DUSP; DUSP domain

    2. XM_040678285.2 → XP_040534219.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:856 → 937
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:54 → 426
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:200 → 728
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:78 → 138
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:748 → 830
      DUSP; DUSP domain

    3. XM_040678286.2 → XP_040534220.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:848 → 929
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:54 → 426
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:200 → 720
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:78 → 138
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:740 → 822
      DUSP; DUSP domain

    4. XM_040678287.2 → XP_040534221.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:811 → 892
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:6 → 378
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:152 → 683
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:30 → 90
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:703 → 785
      DUSP; DUSP domain

    5. XM_040678290.2 → XP_040534224.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00290
      Location:29 → 81
      ZnF_UBP; Ubiquitin Carboxyl-terminal Hydrolase-like zinc finger
      smart00695
      Location:808 → 889
      DUSP; Domain in ubiquitin-specific proteases
      COG5560
      Location:147 → 684
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:441 → 681
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl12116
      Location:700 → 782
      DUSP; DUSP domain

    6. XM_040678291.2 → XP_040534225.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00290
      Location:29 → 81
      ZnF_UBP; Ubiquitin Carboxyl-terminal Hydrolase-like zinc finger
      smart00695
      Location:800 → 881
      DUSP; Domain in ubiquitin-specific proteases
      COG5560
      Location:147 → 676
      UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
      cd02674
      Location:441 → 673
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      cl12116
      Location:692 → 774
      DUSP; DUSP domain

    7. XM_046923056.1 → XP_046779012.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZHN6

    8. XM_046923057.1 → XP_046779013.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZHN6

    9. XM_040678289.1 → XP_040534223.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:811 → 892
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:6 → 378
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:152 → 683
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:30 → 90
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:703 → 785
      DUSP; DUSP domain

    10. XM_040678288.1 → XP_040534222.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZHN6
      Conserved Domains (5) summary
      smart00695
      Location:811 → 892
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:6 → 378
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:152 → 683
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:30 → 90
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:703 → 785
      DUSP; DUSP domain

    11. XM_040678293.2 → XP_040534227.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X7

      UniProtKB/TrEMBL
      A0A8V0ZQA6
      Conserved Domains (5) summary
      smart00695
      Location:767 → 848
      DUSP; Domain in ubiquitin-specific proteases
      COG5207
      Location:4 → 334
      UBP14; Uncharacterized Zn-finger protein, UBP-type [General function prediction only]
      pfam00443
      Location:108 → 639
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam02148
      Location:4 → 46
      zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
      cl12116
      Location:659 → 741
      DUSP; DUSP domain
    Nucleotide Protein
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