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    Fgf8 fibroblast growth factor 8 [ Mus musculus (house mouse) ]

    Gene ID: 14179, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Fgf8provided by MGI
    Official Full Name
    fibroblast growth factor 8provided by MGI
    Primary source
    MGI:MGI:99604
    See related
    Ensembl:ENSMUSG00000025219 AllianceGenome:MGI:99604
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Aigf; Fgf-8; Fgf6c; HBGF-8
    Summary
    Predicted to enable signaling receptor binding activity. Involved in outflow tract septum morphogenesis. Acts upstream of or within several processes, including brain development; circulatory system development; and embryonic morphogenesis. Predicted to be located in external side of plasma membrane. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; branchial arch; embryo ectoderm; embryo mesenchyme; and sensory organ. Used to study DiGeorge syndrome and tetralogy of Fallot. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 6 with or without anosmia and prostate carcinoma in situ. Orthologous to human FGF8 (fibroblast growth factor 8). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in CNS E11.5 (RPKM 1.9), ovary adult (RPKM 1.5) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Fgf8 in Genome Data Viewer
    Location:
    19 C3; 19 38.75 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (45724930..45731380, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (45736491..45742941, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene deleted in primary ciliary dyskinesia Neighboring gene F-box and WD-40 domain protein 4 Neighboring gene STARR-seq mESC enhancer starr_46281 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:45758150-45758404 Neighboring gene CR4 enhancer downstream of Fgf8 Neighboring gene RIKEN cDNA 4933429K18 gene Neighboring gene CR2 enhancer downstream of Fgf8 Neighboring gene Fgf8 enhancer CR1 Neighboring gene STARR-positive B cell enhancer ABC_E11033 Neighboring gene nucleoplasmin 3 Neighboring gene O-GlcNAcase Neighboring gene STARR-positive B cell enhancer ABC_E4286

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Retinoic acid affects craniofacial patterning by changing Fgf8 expression in the pharyngeal ectoderm. Abe M, et al. Dev Growth Differ, 2008 Dec. PMID 19046160
    2. Fgf8-Deficient Mice Compensate for Reduced GnRH Neuronal Population and Exhibit Normal Testicular Function. Zhang W, et al. Front Endocrinol (Lausanne), 2015. PMID 26441841, Free PMC Article
    3. Fibroblast growth factor 8 regulates postnatal development of paraventricular nucleus neuroendocrine cells. Rodriguez KM, et al. Behav Brain Funct, 2015 Nov 4. PMID 26537115, Free PMC Article
    4. Numerous isoforms of Fgf8 reflect its multiple roles in the developing brain. Sunmonu NA, et al. J Cell Physiol, 2011 Jul. PMID 21506104, Free PMC Article
    5. Exogenous fibroblast growth factor 8 rescues development of mouse diastemal vestigial tooth ex vivo. Li L, et al. Dev Dyn, 2011 Jun. PMID 21412937, Free PMC Article

    See all (1000) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Ectopic Activation of Fgf8 in Dental Mesenchyme Causes Incisor Agenesis and Molar Microdontia.
      Title: Ectopic Activation of Fgf8 in Dental Mesenchyme Causes Incisor Agenesis and Molar Microdontia.
    2. Aberrant differentiation of second heart field mesoderm prefigures cellular defects in the outflow tract in response to loss of FGF8.
      Title: Aberrant differentiation of second heart field mesoderm prefigures cellular defects in the outflow tract in response to loss of FGF8.
    3. Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve split-hand/foot malformation type 3.
      Title: Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve split-hand/foot malformation type 3.
    4. Fgf8 promotes survival of nephron progenitors by regulating BAX/BAK-mediated apoptosis.
      Title: Fgf8 promotes survival of nephron progenitors by regulating BAX/BAK-mediated apoptosis.
    5. Fibroblast growth factor 8 (FGF8) up-regulates gelatinase expression in chondrocytes through nuclear factor-kappaB p65.
      Title: Fibroblast growth factor 8 (FGF8) up-regulates gelatinase expression in chondrocytes through nuclear factor-κB p65.
    6. FGF8 induces chemokinesis and regulates condensation of mouse nephron progenitor cells.
      Title: FGF8 induces chemokinesis and regulates condensation of mouse nephron progenitor cells.
    7. Position effects at the FGF8 locus are associated with femoral hypoplasia.
      Title: Position effects at the FGF8 locus are associated with femoral hypoplasia.
    8. Delta-like ligand 4-mediated Notch signaling controls proliferation of second heart field progenitor cells by regulating Fgf8 expression.
      Title: Delta-like ligand 4-mediated Notch signaling controls proliferation of second heart field progenitor cells by regulating Fgf8 expression.
    9. Nephron Progenitor Maintenance Is Controlled through Fibroblast Growth Factors and Sprouty1 Interaction.
      Title: Nephron Progenitor Maintenance Is Controlled through Fibroblast Growth Factors and Sprouty1 Interaction.
    10. Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive intra- and inter-enhancer redundancy.
      Title: Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive intra- and inter-enhancer redundancy.
    Submit: New GeneRIF Correction See all GeneRIFs (138)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC59627

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chemoattractant activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chemoattractant activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables growth factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables growth factor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables type 1 fibroblast growth factor receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables type 1 fibroblast growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables type 2 fibroblast growth factor receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables type 2 fibroblast growth factor receptor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within aorta morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within blood vessel remodeling IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in bone development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in bone development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within branching involved in blood vessel morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within branching involved in salivary gland morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within branching involved in salivary gland morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within branching involved in ureteric bud morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell fate commitment IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within cell migration involved in mesendoderm migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of cell population proliferation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cell proliferation in forebrain IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in central nervous system neuron development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within corticotropin hormone secreting cell differentiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within determination of left/right symmetry IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in dopaminergic neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in dopaminergic neuron differentiation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in dorsal/ventral axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in dorsal/ventral axon guidance ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in dorsal/ventral pattern formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within embryo development ending in birth or egg hatching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryonic heart tube development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryonic hindlimb morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within embryonic neurocranium morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within epithelial to mesenchymal transition involved in endocardial cushion formation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in epithelial to mesenchymal transition involved in endocardial cushion formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in fibroblast growth factor receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within fibroblast growth factor receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within fibroblast growth factor receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within fibroblast growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within forebrain dorsal/ventral pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within forebrain morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in forebrain neuron development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in forebrain neuron development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within generation of neurons IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in gonad development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in gonad development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within heart development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within heart looping IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within heart morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within inner ear morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within kidney development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within larynx morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within limb morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within lung development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within lung morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within male genitalia development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within mesodermal cell migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in metanephros development IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within midbrain-hindbrain boundary development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of mitotic nuclear division IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in motor neuron axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in motor neuron axon guidance ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within negative regulation of apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of cardiac muscle tissue development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of cardiac muscle tissue development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within negative regulation of neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within neural plate morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuroepithelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in neurogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in odontogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of organ growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of organ growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within organ induction IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within otic vesicle formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in otic vesicle formation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within outflow tract morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in outflow tract septum morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within pallium development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pharyngeal system development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of ERK1 and ERK2 cascade IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of cell population proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within positive regulation of cell population proliferation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within positive regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of mitotic nuclear division IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of organ growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of organ growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of peptidyl-tyrosine phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of stem cell proliferation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of odontogenesis of dentin-containing tooth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to organic cyclic compound IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to oxidative stress ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to xenobiotic stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within signal transduction involved in regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of stem cell proliferation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within subpallium development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within telencephalon development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within thyroid gland development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within thyroid gland development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within thyroid-stimulating hormone-secreting cell differentiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    fibroblast growth factor 8
    Names
    androgen-induced growth factor
    fibroblast growth factor 6c
    heparin-binding growth factor 8

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166361.2 → NP_001159833.1  fibroblast growth factor 8 isoform 2 precursor

      See identical proteins and their annotated locations for NP_001159833.1

      Status: VALIDATED

      Source sequence(s)
      AC149086
      Consensus CDS
      CCDS50452.1
      UniProtKB/TrEMBL
      Q80ZL6
      Related
      ENSMUSP00000026240.8, ENSMUST00000026240.14
      Conserved Domains (1) summary
      pfam00167
      Location:81 → 204
      FGF; Fibroblast growth factor

    2. NM_001166362.2 → NP_001159834.1  fibroblast growth factor 8 isoform 3 precursor

      See identical proteins and their annotated locations for NP_001159834.1

      Status: VALIDATED

      Source sequence(s)
      AC149086
      Consensus CDS
      CCDS50451.1
      UniProtKB/TrEMBL
      G3DRA7, Q3V279
      Related
      ENSMUSP00000107559.2, ENSMUST00000111928.8
      Conserved Domains (1) summary
      pfam00167
      Location:52 → 175
      FGF; Fibroblast growth factor

    3. NM_001166363.2 → NP_001159835.1  fibroblast growth factor 8 isoform 4 precursor

      See identical proteins and their annotated locations for NP_001159835.1

      Status: VALIDATED

      Source sequence(s)
      AC149086
      Consensus CDS
      CCDS50450.1
      UniProtKB/TrEMBL
      G3DRA7
      Related
      ENSMUSP00000107558.2, ENSMUST00000111927.8
      Conserved Domains (1) summary
      pfam00167
      Location:41 → 164
      FGF; Fibroblast growth factor

    4. NM_001379139.1 → NP_001366068.1  fibroblast growth factor 8 isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AC149086
      Conserved Domains (1) summary
      pfam00167
      Location:134 → 257
      FGF; Fibroblast growth factor

    5. NM_001379140.1 → NP_001366069.1  fibroblast growth factor 8 isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AC149086
      Conserved Domains (1) summary
      pfam00167
      Location:116 → 239
      FGF; Fibroblast growth factor

    6. NM_001403100.1 → NP_001390029.1  fibroblast growth factor 8 isoform 7 precursor

      Status: VALIDATED

      Source sequence(s)
      AC149086

    7. NM_010205.3 → NP_034335.1  fibroblast growth factor 8 isoform 1 precursor

      See identical proteins and their annotated locations for NP_034335.1

      Status: VALIDATED

      Source sequence(s)
      AC149086
      Consensus CDS
      CCDS29864.1
      UniProtKB/Swiss-Prot
      P37237
      Related
      ENSMUSP00000026241.6, ENSMUST00000026241.12
      Conserved Domains (1) summary
      pfam00167
      Location:105 → 228
      FGF; Fibroblast growth factor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      45724930..45731380 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526668.4 → XP_006526731.1  fibroblast growth factor 8 isoform X2

      See identical proteins and their annotated locations for XP_006526731.1

      UniProtKB/TrEMBL
      D3Z207, G3DRA7
      Related
      ENSMUSP00000107556.2, ENSMUST00000111925.2
      Conserved Domains (1) summary
      pfam00167
      Location:70 → 193
      FGF; Fibroblast growth factor
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P37237.1 GenPept UniProtKB/Swiss-Prot:P37237

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous