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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001190809.2 → NP_001177738.1 probable ATP-dependent RNA helicase DHX35 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) is missing an in-frame coding exon compared to variant 1, resulting in a shorter isoform (2) lacking an internal protein segment compared to isoform 1.
- Source sequence(s)
-
BC033453, DA725122
- Consensus CDS
-
CCDS54463.1
- UniProtKB/TrEMBL
-
Q5THR1
- Related
- ENSP00000362420.3, ENST00000373323.8
- Conserved Domains (5) summary
-
- smart00490
Location:270 → 365
- HELICc; helicase superfamily c-terminal domain
- smart00847
Location:434 → 518
- HA2; Helicase associated domain (HA2) Add an annotation
- COG1643
Location:21 → 651
- HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
- cd00046
Location:59 → 180
- DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
- pfam07717
Location:553 → 652
- OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
-
NM_021931.4 → NP_068750.2 probable ATP-dependent RNA helicase DHX35 isoform 1
See identical proteins and their annotated locations for NP_068750.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
BC033453, DA725122
- Consensus CDS
-
CCDS13310.1
- UniProtKB/Swiss-Prot
- A2RTX3, B4E0J0, F5GXM6, Q5THR0, Q9H4H7, Q9H5Z1, Q9H6T6
- UniProtKB/TrEMBL
-
Q5THR1
- Related
- ENSP00000252011.3, ENST00000252011.8
- Conserved Domains (1) summary
-
- COG1643
Location:21 → 682
- HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
RNA
-
NR_033905.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate acceptor splice site at an internal exon compared to variant 1, resulting in a frame-shift. This variant is represented as non-coding because the use of the 5'-most translational initiation codon (flanked by a strong Kozak signal), as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AK296793, BC033453, DA725122
- Related
-
ENST00000484417.5