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    Nkapd1 NKAP domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 270156, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Nkapd1provided by MGI
    Official Full Name
    NKAP domain containing 1provided by MGI
    Primary source
    MGI:MGI:2143205
    See related
    Ensembl:ENSMUSG00000059820 AllianceGenome:MGI:2143205
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ahed; Gm639
    Summary
    Predicted to enable identical protein binding activity. Orthologous to human NKAPD1 (NKAP domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in kidney adult (RPKM 8.0), CNS E11.5 (RPKM 6.6) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Nkapd1 in Genome Data Viewer
    Location:
    9 A5.3; 9 27.75 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (50516542..50528567, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (50605240..50617464, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene interleukin 18 Neighboring gene testis expressed 12 Neighboring gene succinate dehydrogenase complex, subunit D, integral membrane protein Neighboring gene translocase of inner mitochondrial membrane 8B Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:50425377-50425486 Neighboring gene PIH1 domain containing 2 Neighboring gene STARR-seq mESC enhancer starr_24113 Neighboring gene dihydrolipoamide S-acetyltransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A newly identified gene Ahed plays essential roles in murine haematopoiesis. Nakai R, et al. Nat Commun, 2024 Jun 25. PMID 38918373, Free PMC Article
    2. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein NKAPD1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134902.2 → NP_001128374.1  uncharacterized protein NKAPD1 isoform 1

      See identical proteins and their annotated locations for NP_001128374.1

      Status: VALIDATED

      Source sequence(s)
      AC025500
      Consensus CDS
      CCDS23166.2
      UniProtKB/TrEMBL
      E9PUQ3, Q6NX79
      Related
      ENSMUSP00000133259.2, ENSMUST00000171462.8
      Conserved Domains (1) summary
      pfam15692
      Location:93 → 147
      NKAP; NF-kappa-B-activating protein

    2. NM_001360340.2 → NP_001347269.1  uncharacterized protein NKAPD1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC025500
      Consensus CDS
      CCDS23166.2
      UniProtKB/TrEMBL
      E9PUQ3, Q6NX79
      Conserved Domains (1) summary
      pfam15692
      Location:93 → 147
      NKAP; NF-kappa-B-activating protein

    3. NM_001411363.1 → NP_001398292.1  uncharacterized protein NKAPD1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025500
      UniProtKB/TrEMBL
      Q6NX79

    4. NM_001411364.1 → NP_001398293.1  uncharacterized protein NKAPD1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC025500
      UniProtKB/TrEMBL
      Q6NX79

    5. NM_212449.3 → NP_997614.2  uncharacterized protein NKAPD1 isoform 1

      See identical proteins and their annotated locations for NP_997614.2

      Status: VALIDATED

      Source sequence(s)
      AC025500
      Consensus CDS
      CCDS23166.2
      UniProtKB/TrEMBL
      E9PUQ3, Q6NX79
      Related
      ENSMUSP00000123319.2, ENSMUST00000131351.8
      Conserved Domains (1) summary
      pfam15692
      Location:93 → 147
      NKAP; NF-kappa-B-activating protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      50516542..50528567 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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