ITGB1BP1 integrin subunit beta 1 binding protein 1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: ITGB1BP1provided by HGNC
Official Full Name: integrin subunit beta 1 binding protein 1provided by HGNC
Primary source: HGNC:HGNC:23927
See related: Ensembl:ENSG00000119185 MIM:607153; AllianceGenome:HGNC:23927
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: ICAP1; ICAP1A; ICAP1B; ICAP-1A; ICAP-1B; ICAP-1alpha
Summary: The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]
Expression: Broad expression in fat (RPKM 65.6), brain (RPKM 11.2) and 22 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 2p25.1

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	2	NC_000002.12 (9403475..9423569, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	2	NC_060926.1 (9428778..9448648, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	2	NC_000002.11 (9543604..9563698, complement)

Chromosome 2 - NC_000002.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation.
Title: Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation.
ICAP-1 monoubiquitylation helps in switching from ROCK2-mediated to MRCKalpha-mediated cell contractility.
Title: ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKα balance.
nuclear-cytoplasmic shuttling of ICAP1 influences both integrin activation and KRIT1 localization, presumably impacting nuclear functions of KRIT1.
Title: Nuclear Localization of Integrin Cytoplasmic Domain-associated Protein-1 (ICAP1) Influences β1 Integrin Activation and Recruits Krev/Interaction Trapped-1 (KRIT1) to the Nucleus.
The cocrystal structure of ICAP1 in complex with krev interaction trapped protein (KRIT)1 is characterized here.
Title: Cocrystal structure of the ICAP1 PTB domain in complex with a KRIT1 peptide.
The structural basis for KRIT1 antagonized ICAP1-modulated integrin-beta1 activation.
Title: Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation.
Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway.
Title: Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway.
Identify ICAP1 as a novel regulator to prevent excessive sprouting angiogenesis.
Title: Integrin cytoplasmic domain-associated protein-1 attenuates sprouting angiogenesis.
integrin cytoplasmic domain-associated protein-1 alpha (icap1alpha) act concordantly to play a critical role in beta1-integrin-mediated cell proliferation.
Title: Krit1 modulates beta 1-integrin-mediated endothelial cell proliferation.
Observational study of gene-disease association. (HuGE Navigator)
Title: Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
ICAP-1 shuttles between the nucleus and cytoplasm in a beta1 integrin-dependent manner
Title: Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.

Submit: New GeneRIF Correction See all GeneRIFs (14)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

SHGC-30375 (e-PCR)
- UniSTS:28997

RH98873 (e-PCR)
- UniSTS:91721

D2S1665E (e-PCR)
- UniSTS:38233

STS-N29464 (e-PCR)
- UniSTS:70759

SHGC-64269 (e-PCR)
- UniSTS:80805

RH78234 (e-PCR)
- UniSTS:11687

RH78071 (e-PCR)
- UniSTS:47814

RH16639 (e-PCR)
- UniSTS:56787

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables GDP-dissociation inhibitor activity	IDA Inferred from Direct Assay more info	PubMed
enables integrin binding	IBA Inferred from Biological aspect of Ancestor more info
enables integrin binding	IDA Inferred from Direct Assay more info	PubMed
enables integrin binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in Notch signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in activation of protein kinase B activity	IDA Inferred from Direct Assay more info	PubMed
involved_in biomineral tissue development	IEA Inferred from Electronic Annotation more info
involved_in blood vessel diameter maintenance	IDA Inferred from Direct Assay more info	PubMed
involved_in blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA Inferred from Direct Assay more info	PubMed
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in cell migration	TAS Traceable Author Statement more info	PubMed
involved_in cell-matrix adhesion	IDA Inferred from Direct Assay more info	PubMed
involved_in cellular response to fibroblast growth factor stimulus	IDA Inferred from Direct Assay more info	PubMed
involved_in cellular response to vascular endothelial growth factor stimulus	IDA Inferred from Direct Assay more info	PubMed
involved_in integrin activation	IDA Inferred from Direct Assay more info	PubMed
involved_in integrin activation	ISS Inferred from Sequence or Structural Similarity more info
involved_in integrin-mediated signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in intracellular signal transduction	TAS Traceable Author Statement more info	PubMed
involved_in myoblast migration	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of ERK1 and ERK2 cascade	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of cell adhesion involved in substrate-bound cell migration	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of cell migration involved in sprouting angiogenesis	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of cell population proliferation	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of fibroblast migration	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of focal adhesion assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of focal adhesion assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of protein binding	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of protein kinase activity	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of protein targeting to membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of substrate adhesion-dependent cell spreading	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of substrate adhesion-dependent cell spreading	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of Notch signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of cell division	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of cell population proliferation	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of endothelial cell migration	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of focal adhesion assembly	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of protein targeting to membrane	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of stress fiber assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in protein localization to plasma membrane	IDA Inferred from Direct Assay more info	PubMed
involved_in receptor clustering	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of GTPase activity	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of cell adhesion mediated by integrin	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of integrin-mediated signaling pathway	ISS Inferred from Sequence or Structural Similarity more info
involved_in tube formation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
is_active_in cell periphery	IBA Inferred from Biological aspect of Ancestor more info
located_in cell periphery	IDA Inferred from Direct Assay more info	PubMed
located_in centriolar satellite	IDA Inferred from Direct Assay more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoskeleton	ISS Inferred from Sequence or Structural Similarity more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
NOT located_in focal adhesion	IDA Inferred from Direct Assay more info	PubMed
is_active_in lamellipodium	IBA Inferred from Biological aspect of Ancestor more info
located_in lamellipodium	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
located_in nuclear body	IDA Inferred from Direct Assay more info
located_in nucleoplasm	IDA Inferred from Direct Assay more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in perinuclear region of cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in ruffle	IBA Inferred from Biological aspect of Ancestor more info
located_in ruffle	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: integrin beta-1-binding protein 1

Names: bodenin; integrin cytoplasmic domain-associated protein 1; integrin cytoplasmic domain-associated protein 1-alpha; integrin cytoplasmic domain-associated protein 1-beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001319066.2 → NP_001305995.1 integrin beta-1-binding protein 1 isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (1). Variants 1, 3, 4, and 5 all encode the same isoform (1).

Source sequence(s)

AC080162, AI144519, AU280516, BC012264, CA428076

Consensus CDS

CCDS1662.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
NM_001319067.2 → NP_001305996.1 integrin beta-1-binding protein 1 isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. Variants 1, 3, 4, and 5 all encode the same isoform (1).

Source sequence(s)

AC080162, AI336197, AU280516, BC012264, CA428076

Consensus CDS

CCDS1662.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
NM_001319068.2 → NP_001305997.1 integrin beta-1-binding protein 1 isoform 1

Status: REVIEWED

Description

Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 3. Variants 1, 3, 4, and 5 all encode the same isoform (1).

Source sequence(s)

AC080162, BU520903, CA428076

Consensus CDS

CCDS1662.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
NM_001319069.2 → NP_001305998.1 integrin beta-1-binding protein 1 isoform 3

Status: REVIEWED

Description

Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence and lacks two alternate exons compared to variant 3. The resulting isoform (3) has a shorter and distinct N-terminus compared to isoform 1.

Source sequence(s)

AC080162, CA428076, DC321859, DC361372

UniProtKB/TrEMBL

B4DQY5

Conserved Domains (1) summary

cl17171
Location:7 → 156

PH-like; Pleckstrin homology-like domain
NM_001319070.2 → NP_001305999.1 integrin beta-1-binding protein 1 isoform 4

Status: REVIEWED

Description

Transcript Variant: This variant (7) differs in the 5' UTR and lacks an alternate in-frame segment compared to variant 3. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.

Source sequence(s)

AC080162, BY996754, CA428076, DC361372

Conserved Domains (1) summary

cl17171
Location:23 → 128

PH-like; Pleckstrin homology-like domain
NM_001369744.1 → NP_001356673.1 integrin beta-1-binding protein 1 isoform 1

Status: REVIEWED

Source sequence(s)

AC080162

Consensus CDS

CCDS1662.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Related

ENSP00000353850.3, ENST00000360635.7

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
NM_001369745.1 → NP_001356674.1 integrin beta-1-binding protein 1 isoform 1

Status: REVIEWED

Source sequence(s)

AC080162

Consensus CDS

CCDS1662.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
NM_001369746.1 → NP_001356675.1 integrin beta-1-binding protein 1 isoform 1

Status: REVIEWED

Source sequence(s)

AC080162

Consensus CDS

CCDS1662.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
NM_001369747.1 → NP_001356676.1 integrin beta-1-binding protein 1 isoform 2

Status: REVIEWED

Source sequence(s)

AC080162

Consensus CDS

CCDS1663.1

UniProtKB/TrEMBL

C9JBU8

Related

ENSP00000419524.1, ENST00000488451.5

Conserved Domains (1) summary

cl17171
Location:1 → 150

PH-like; Pleckstrin homology-like domain
NM_001369748.1 → NP_001356677.1 integrin beta-1-binding protein 1 isoform 1

Status: REVIEWED

Source sequence(s)

AC080162

Consensus CDS

CCDS1662.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
NM_001369749.2 → NP_001356678.1 integrin beta-1-binding protein 1 isoform 1

Status: REVIEWED

Source sequence(s)

AC080162

Consensus CDS

CCDS1662.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
NM_001369750.1 → NP_001356679.1 integrin beta-1-binding protein 1 isoform 2

Status: REVIEWED

Source sequence(s)

AC080162

Consensus CDS

CCDS1663.1

UniProtKB/TrEMBL

C9JBU8

Conserved Domains (1) summary

cl17171
Location:1 → 150

PH-like; Pleckstrin homology-like domain
NM_004763.5 → NP_004754.1 integrin beta-1-binding protein 1 isoform 1

See identical proteins and their annotated locations for NP_004754.1

Status: REVIEWED

Description

Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 3, 4, and 5 all encode the same isoform (1).

Source sequence(s)

AC080162, BC012264, CA428076, DC361372

Consensus CDS

CCDS1662.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Related

ENSP00000347504.4, ENST00000355346.9

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
NM_022334.5 → NP_071729.1 integrin beta-1-binding protein 1 isoform 2

See identical proteins and their annotated locations for NP_071729.1

Status: REVIEWED

Description

Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 3. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.

Source sequence(s)

AC080162, BG032225, CA428076, DC361372

Consensus CDS

CCDS1663.1

UniProtKB/TrEMBL

C9JBU8

Related

ENSP00000238091.4, ENST00000238091.8

Conserved Domains (1) summary

cl17171
Location:1 → 150

PH-like; Pleckstrin homology-like domain

RNA

NR_134951.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (8) contains two alternate exons in place of the first two exons compared to variant 3. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.

Source sequence(s)

AC080162, BC012264, BE146261, CA428076, DB167886
NR_134952.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (9) differs in the 5' end, uses an alternate internal splice junction, and lacks an alternate 3' exon compared to variant 3. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AC080162, AK092115, CA428076, DC361372
NR_134953.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (10) differs in the 5' end and lacks an alternate 3' exon compared to variant 3. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.

Source sequence(s)

AC080162, CA428076, DA751320, DC361372
NR_134954.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (11) differs in the 5' end and uses an alternate splice junction in the 3' end compared to variant 3. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AC080162, BQ421551, CA428076, DC361372
NR_134955.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (12) differs in the 5' end and uses an alternate splice junction in the 3' end compared to variant 3. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AC080162, BC012264, CA428076, DA087859, DC361372
NR_134956.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (13) differs in the 5' end and lacks an alternate internal exon compared to variant 3. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AC080162, BX647099, CA428076, DC361372
NR_134957.2 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (14) differs in the 5' end and lacks an alternate internal exon compared to variant 3. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.

Source sequence(s)

AC080162, CA428076, CT002942, DC361372

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000002.12 Reference GRCh38.p14 Primary Assembly

Range

9403475..9423569 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_047446338.1 → XP_047302294.1 integrin beta-1-binding protein 1 isoform X2
XM_047446337.1 → XP_047302293.1 integrin beta-1-binding protein 1 isoform X2
XM_006711903.4 → XP_006711966.1 integrin beta-1-binding protein 1 isoform X1

See identical proteins and their annotated locations for XP_006711966.1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein
XM_047446336.1 → XP_047302292.1 integrin beta-1-binding protein 1 isoform X2
XM_017005270.2 → XP_016860759.1 integrin beta-1-binding protein 1 isoform X2

UniProtKB/TrEMBL

C9JBU8

Conserved Domains (1) summary

cl17171
Location:1 → 150

PH-like; Pleckstrin homology-like domain
XM_017005267.2 → XP_016860756.1 integrin beta-1-binding protein 1 isoform X1

UniProtKB/Swiss-Prot

D6W4Y9, O14713, O14714, Q53RS0

UniProtKB/TrEMBL

A8K1A2, Q6IAZ8

Conserved Domains (1) summary

pfam10480
Location:1 → 200

ICAP-1_inte_bdg; Beta-1 integrin binding protein