U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Nucleotide

    • Showing Current items.

    LOC127823012 OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr11:126477779-126478464 [ Homo sapiens (human) ]

    Gene ID: 127823012, updated on 12-Sep-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    LOC127823012
    Gene description
    OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr11:126477779-126478464
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors and is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See LOC127823012 in Genome Data Viewer
    Location:
    chromosome: 11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (126607884..126608569)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (126639339..126640020)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (126477779..126478464)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:126224473-126225216 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126225217-126225958 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126225959-126226702 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126228189-126228930 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126234481-126234998 Neighboring gene decapping enzyme, scavenger Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126263623-126264550 Neighboring gene ST3 beta-galactoside alpha-2,3-sialyltransferase 4 Neighboring gene Sharpr-MPRA regulatory region 5906 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4052 Neighboring gene G-quadruplex forming sequence containing lncRNA Neighboring gene ReSE screen-validated silencer GRCh37_chr11:126304382-126304547 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126306384-126307384 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126312444-126313126 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126314549-126315102 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126315103-126315656 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126316770-126317338 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5710 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126336189-126336738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126336739-126337286 Neighboring gene kirre like nephrin family adhesion molecule 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126348793-126349294 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126356175-126356675 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126364262-126365032 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126389731-126390232 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126393473-126393972 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126398704-126399204 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126399205-126399705 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126413360-126413866 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126413867-126414371 Neighboring gene KIRREL3 antisense RNA 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:126434244-126434929 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126437665-126438165 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:126455626-126456345 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:126456346-126457066 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:126457067-126457785 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126462463-126462992 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126462993-126463521 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:126471727-126472504 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr11:126477093-126477778 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:126478465-126479149 Neighboring gene uncharacterized LOC101929427 Neighboring gene uncharacterized LOC124902785

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

    Go to the top of the page Help

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See Variation Viewer (GRCh37.p13)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_124451.1 

      Range
      101..786
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      126607884..126608569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      126639339..126640020
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases