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    Smim5 small integral membrane protein 5 [ Mus musculus (house mouse) ]

    Gene ID: 66528, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Smim5provided by MGI
    Official Full Name
    small integral membrane protein 5provided by MGI
    Primary source
    MGI:MGI:1913778
    See related
    Ensembl:ENSMUSG00000048442 AllianceGenome:MGI:1913778
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2210020M01Rik
    Summary
    Predicted to be located in membrane. Is expressed in choroid invagination; clavicle; diencephalon roof plate; and metencephalon part of 4th ventricle choroid plexus. Orthologous to human SMIM5 (small integral membrane protein 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in liver E14.5 (RPKM 3.3), liver E14 (RPKM 3.2) and 21 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Smim5 in Genome Data Viewer
    Location:
    11 E2; 11 80.91 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115789575..115797095)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115897806..115906269)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_31175 Neighboring gene LLGL2 scribble cell polarity complex component Neighboring gene STARR-seq mESC enhancer starr_31178 Neighboring gene myosin XVB Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115759828-115760025 Neighboring gene RecQ protein-like 5 Neighboring gene endoregulin Neighboring gene STARR-positive B cell enhancer ABC_E1850 Neighboring gene STARR-seq mESC enhancer starr_31180 Neighboring gene SAP30 binding protein Neighboring gene predicted gene, 39474

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    small integral membrane protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183259.3 → NP_899082.1  small integral membrane protein 5

      See identical proteins and their annotated locations for NP_899082.1

      Status: PROVISIONAL

      Source sequence(s)
      AK004370, AL645647, AW124215
      Consensus CDS
      CCDS70347.1
      UniProtKB/Swiss-Prot
      Q8BT42
      Related
      ENSMUSP00000139148.2, ENSMUST00000152171.8
      Conserved Domains (1) summary
      cl24410
      Location:5 → 75
      CASIMO1; Cancer Associated Small Integral Membrane Open reading frame 1 (CASIMO1)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      115789575..115797095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533943.5 → XP_006534006.1  small integral membrane protein 5 isoform X2

      See identical proteins and their annotated locations for XP_006534006.1

      UniProtKB/Swiss-Prot
      Q8BT42
      Related
      ENSMUSP00000138928.2, ENSMUST00000142089.2
      Conserved Domains (1) summary
      cl24410
      Location:5 → 75
      CASIMO1; Cancer Associated Small Integral Membrane Open reading frame 1 (CASIMO1)

    2. XM_006533942.4 → XP_006534005.1  small integral membrane protein 5 isoform X1

      Conserved Domains (1) summary
      cd20254
      Location:29 → 99
      CASIMO1_SMIM5; small integral membrane protein 5 (SMIM5) of CASIMO1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NR_027815.1: Suppressed sequence

      Description
      NR_027815.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BT42.1 GenPept UniProtKB/Swiss-Prot:Q8BT42

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