ERC1 ELKS/RAB6-interacting/CAST family member 1 [Homo sapiens (human)] - Gene

Summary

Official Symbol: ERC1provided by HGNC
Official Full Name: ELKS/RAB6-interacting/CAST family member 1provided by HGNC
Primary source: HGNC:HGNC:17072
See related: Ensembl:ENSG00000082805 MIM:607127; AllianceGenome:HGNC:17072
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: ELKS; Cast2; ERC-1; RAB6IP2
Summary: The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Expression: Ubiquitous expression in thyroid (RPKM 7.0), esophagus (RPKM 6.1) and 25 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 12p13.33

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	12	NC_000012.12 (989959..1495933)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	12	NC_060936.1 (985850..1490194)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	12	NC_000012.11 (1100389..1605099)

Chromosome 12 - NC_000012.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interfering with the ERC1-LL5beta interaction disrupts plasma membrane-Associated platforms and affects tumor cell motility.
Title: Interfering with the ERC1-LL5β interaction disrupts plasma membrane-Associated platforms and affects tumor cell motility.
Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins.
Title: Oligomerized liprin-α promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins.
Volumetric GWAS of medial temporal lobe structures identifies an ERC1 locus using ADNI high-resolution T2-weighted MRI data.
Title: Volumetric GWAS of medial temporal lobe structures identifies an ERC1 locus using ADNI high-resolution T2-weighted MRI data.
The ELKS forms a potent insulin secretion complex with L-type voltage-dependent Ca(2+) channels on the vascular-facing plasma membrane of beta-cells, enabling polarized Ca(2+) influx and first-phase insulin secretion from islets.
Title: Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells.
Several studies had established that ELKS is a redundant scaffold at the active zone, and that disruption of this scaffold impairs fusion of synaptic vesicles. In non-neuronal cells, scaffolding and exocytotic functions of ELKS seem to be important for constitutive secretion of other cargo. [review]
Title: ELKS active zone proteins as multitasking scaffolds for secretion.
Knockdown of ERC1, RAB4B, COPA, and COPB2, caused profound loss of virus production.
Title: Identification of Host Factors Involved in Human Cytomegalovirus Replication, Assembly, and Egress Using a Two-Step Small Interfering RNA Screen.
The results indicate that liprin-alpha1, LL5 and ERC1 define a novel dynamic membrane-less compartment that regulates matrix degradation by affecting invadosome motility.
Title: Identification of a membrane-less compartment regulating invadosome function and motility.
ELKS removal has differential, synapse-specific effects on readily releasable vesicles and probability of release, and findings establish important roles for ELKS N-terminal domains in synaptic vesicle priming.
Title: ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains.
Liprin-alpha1, ERC1a and LL5 also define new highly polarized and dynamic cytoplasmic structures uniquely localized near the protruding cell edge
Title: Liprin-α1, ERC1 and LL5 define polarized and dynamic structures that are implicated in cell migration.
a new, but rare, antigen in Lambert-Eaton myasthenic syndrome
Title: Antibodies to active zone protein ERC1 in Lambert-Eaton myasthenic syndrome.

Submit: New GeneRIF Correction See all GeneRIFs (17)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

G41233 (e-PCR)
- UniSTS:26135

RH91161 (e-PCR)
- UniSTS:90904

RH120809 (e-PCR)
- UniSTS:132890

D12S1285 (e-PCR)
- UniSTS:70426

SHGC-144473 (e-PCR)
- UniSTS:182554

D12S2047 (e-PCR)
- UniSTS:43571

D12S1406 (e-PCR)
- UniSTS:69189

G41231 (e-PCR)
- UniSTS:50007

G41234 (e-PCR)
- UniSTS:11352

L18426 (e-PCR)
- UniSTS:34648

WI-13645 (e-PCR)
- UniSTS:81508

G42667 (e-PCR)
- UniSTS:94567

D12S40 (e-PCR)
- UniSTS:147064

G24041 (e-PCR)
- UniSTS:81534

G41235 (e-PCR)
- UniSTS:31871

D12S388 (e-PCR)
- UniSTS:148608

D12S389 (e-PCR), detects polymorphism
- UniSTS:148609

SHGC-152870 (e-PCR)
- UniSTS:173194

RH118903 (e-PCR)
- UniSTS:138895

A004N30 (e-PCR)
- UniSTS:67732

RH45217 (e-PCR)
- UniSTS:58518

D12S1227E (e-PCR)
- UniSTS:151474

D12S972 (e-PCR)
- UniSTS:149943

STS-W47124 (e-PCR)
- UniSTS:76226

G41232 (e-PCR)
- UniSTS:41416

G41791 (e-PCR)
- UniSTS:46280

D12S1587 (e-PCR), detects polymorphism
- UniSTS:7886

RH48779 (e-PCR)
- UniSTS:92113

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables PDZ domain binding	ISS Inferred from Sequence or Structural Similarity more info
enables cadherin binding	HDA more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables small GTPase binding	ISS Inferred from Sequence or Structural Similarity more info
enables structural constituent of presynaptic active zone	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in I-kappaB phosphorylation	IDA Inferred from Direct Assay more info	PubMed
involved_in maintenance of presynaptic active zone structure	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of NF-kappaB transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in retrograde transport, endosome to Golgi	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
part_of IkappaB kinase complex	IDA Inferred from Direct Assay more info	PubMed
located_in anchoring junction	IEA Inferred from Electronic Annotation more info
located_in centrosome	IDA Inferred from Direct Assay more info	PubMed
located_in ciliary basal body	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in podosome	ISS Inferred from Sequence or Structural Similarity more info
is_active_in presynaptic active zone cytoplasmic component	IBA Inferred from Biological aspect of Ancestor more info
located_in presynaptic membrane	TAS Traceable Author Statement more info	PubMed
located_in synapse	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: ELKS/Rab6-interacting/CAST family member 1

Names: RAB6 interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001301248.1 → NP_001288177.1 ELKS/Rab6-interacting/CAST family member 1 isoform zeta

Status: REVIEWED

Description

Transcript Variant: This variant (zeta) contains an additional exon that results in an alternate 3' coding region and 3' UTR, compared to variant epsilon. The encoded isoform (zeta) has a distinct C-terminus and is shorter than isoform epsilon. The 5' UTR of this variant is incomplete due to lack of full-length transcript support and splice site ambiguity in the 5'-most exon.

Source sequence(s)

AC004671, AC004803, BC144287, BM984956

Consensus CDS

CCDS76504.1

UniProtKB/TrEMBL

G8JLD3

Related

ENSP00000347621.5, ENST00000355446.9

Conserved Domains (3) summary

pfam10174
Location:155 → 982

Cast; RIM-binding protein of the cytomatrix active zone

pfam10211
Location:767 → 832

Ax_dynein_light; Axonemal dynein light chain

cl21478
Location:918 → 989

ATP-synt_B; ATP synthase B/B' CF(0)
NM_178039.4 → NP_829883.1 ELKS/Rab6-interacting/CAST family member 1 isoform delta

See identical proteins and their annotated locations for NP_829883.1

Status: REVIEWED

Description

Transcript Variant: This variant (delta) lacks an alternate in-frame exon in the central coding region, compared to variant epsilon, resulting in a shorter isoform (delta), compared to isoform epsilon.

Source sequence(s)

AB053470, AC004671, AC004803, BM984956, DR000847

Consensus CDS

CCDS53732.1

UniProtKB/Swiss-Prot

Q8IUD2

Related

ENSP00000438546.1, ENST00000543086.7

Conserved Domains (4) summary

pfam09457
Location:1040 → 1080

RBD-FIP; FIP domain

pfam10174
Location:155 → 954

Cast; RIM-binding protein of the cytomatrix active zone

pfam10211
Location:739 → 804

Ax_dynein_light; Axonemal dynein light chain

cl21478
Location:890 → 961

ATP-synt_B; ATP synthase B/B' CF(0)
NM_178040.4 → NP_829884.1 ELKS/Rab6-interacting/CAST family member 1 isoform epsilon

See identical proteins and their annotated locations for NP_829884.1

Status: REVIEWED

Description

Transcript Variant: This variant (epsilon) encodes the longest isoform (epsilon).

Source sequence(s)

AB053471, AC004671, AC004672, AC004803, BM984956, DR000847

Consensus CDS

CCDS8508.1

UniProtKB/Swiss-Prot

A2RU77, A7E295, D3DUP7, D3DUP8, Q6NVK2, Q8IUD2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1

Related

ENSP00000354158.3, ENST00000360905.9

Conserved Domains (4) summary

pfam09457
Location:1068 → 1108

RBD-FIP; FIP domain

pfam10174
Location:155 → 982

Cast; RIM-binding protein of the cytomatrix active zone

pfam10211
Location:767 → 832

Ax_dynein_light; Axonemal dynein light chain

cl21478
Location:918 → 989

ATP-synt_B; ATP synthase B/B' CF(0)

RNA

NR_027946.3 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (alpha) uses an alternate splice site in the 5' terminal exon, lacks two internal exons, and contains two additional exons, compared to variant epsilon. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant epsilon, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AB015617, AC004671, AC004803, BM984956, DR000847
NR_027948.3 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (beta) uses an alternate splice site in the 5' terminal exon, lacks one internal exon, and contains two additional exons, compared to variant epsilon. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant epsilon, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AB053468, AC004671, AC004803, BM984956, DR000847
NR_027949.3 RNA Sequence

Status: REVIEWED

Description

Transcript Variant: This variant (gamma) lacks five internal exons and contains two additional exons, compared to variant epsilon. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant epsilon, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AB053469, AC004671, AC004803, BM984956, DR000847

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000012.12 Reference GRCh38.p14 Primary Assembly

Range

989959..1495933

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_047428566.1 → XP_047284522.1 ELKS/Rab6-interacting/CAST family member 1 isoform X8

UniProtKB/Swiss-Prot

A2RU77, A7E295, D3DUP7, D3DUP8, Q6NVK2, Q8IUD2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1
XM_047428562.1 → XP_047284518.1 ELKS/Rab6-interacting/CAST family member 1 isoform X4
XM_017019055.3 → XP_016874544.1 ELKS/Rab6-interacting/CAST family member 1 isoform X1
XM_047428563.1 → XP_047284519.1 ELKS/Rab6-interacting/CAST family member 1 isoform X7
XM_047428558.1 → XP_047284514.1 ELKS/Rab6-interacting/CAST family member 1 isoform X2
XM_047428570.1 → XP_047284526.1 ELKS/Rab6-interacting/CAST family member 1 isoform X9
XM_047428576.1 → XP_047284532.1 ELKS/Rab6-interacting/CAST family member 1 isoform X12
XM_017019054.2 → XP_016874543.1 ELKS/Rab6-interacting/CAST family member 1 isoform X1
XM_047428557.1 → XP_047284513.1 ELKS/Rab6-interacting/CAST family member 1 isoform X2
XM_047428561.1 → XP_047284517.1 ELKS/Rab6-interacting/CAST family member 1 isoform X4
XM_047428565.1 → XP_047284521.1 ELKS/Rab6-interacting/CAST family member 1 isoform X8

UniProtKB/Swiss-Prot

A2RU77, A7E295, D3DUP7, D3DUP8, Q6NVK2, Q8IUD2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1
XM_047428568.1 → XP_047284524.1 ELKS/Rab6-interacting/CAST family member 1 isoform X9
XM_047428572.1 → XP_047284528.1 ELKS/Rab6-interacting/CAST family member 1 isoform X10
XM_047428574.1 → XP_047284530.1 ELKS/Rab6-interacting/CAST family member 1 isoform X12
XM_047428579.1 → XP_047284535.1 ELKS/Rab6-interacting/CAST family member 1 isoform X15
XM_017019052.2 → XP_016874541.1 ELKS/Rab6-interacting/CAST family member 1 isoform X1
XM_017019061.2 → XP_016874550.1 ELKS/Rab6-interacting/CAST family member 1 isoform X5

Conserved Domains (3) summary

pfam09457
Location:1075 → 1115

RBD-FIP; FIP domain

pfam10174
Location:155 → 989

Cast; RIM-binding protein of the cytomatrix active zone

cl21478
Location:925 → 996

ATP-synt_B; ATP synthase B/B' CF(0)
XM_017019069.2 → XP_016874558.1 ELKS/Rab6-interacting/CAST family member 1 isoform X13
XM_017019059.2 → XP_016874548.1 ELKS/Rab6-interacting/CAST family member 1 isoform X3
XM_017019063.2 → XP_016874552.1 ELKS/Rab6-interacting/CAST family member 1 isoform X7

Conserved Domains (4) summary

pfam09457
Location:1071 → 1111

RBD-FIP; FIP domain

pfam10174
Location:155 → 985

Cast; RIM-binding protein of the cytomatrix active zone

pfam10211
Location:770 → 835

Ax_dynein_light; Axonemal dynein light chain

cl21478
Location:921 → 992

ATP-synt_B; ATP synthase B/B' CF(0)
XM_017019057.2 → XP_016874546.1 ELKS/Rab6-interacting/CAST family member 1 isoform X2
XM_017019062.2 → XP_016874551.1 ELKS/Rab6-interacting/CAST family member 1 isoform X6

UniProtKB/TrEMBL

X6RLX0

Related

ENSP00000442739.2, ENST00000546231.6

Conserved Domains (3) summary

pfam09457
Location:1072 → 1112

RBD-FIP; FIP domain

pfam10174
Location:155 → 986

Cast; RIM-binding protein of the cytomatrix active zone

cl21478
Location:922 → 993

ATP-synt_B; ATP synthase B/B' CF(0)
XM_017019060.2 → XP_016874549.1 ELKS/Rab6-interacting/CAST family member 1 isoform X4

Conserved Domains (1) summary

COG1196
Location:261 → 986

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
XM_017019064.2 → XP_016874553.1 ELKS/Rab6-interacting/CAST family member 1 isoform X8

UniProtKB/Swiss-Prot

A2RU77, A7E295, D3DUP7, D3DUP8, Q6NVK2, Q8IUD2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1

Related

ENSP00000380386.4, ENST00000397203.7

Conserved Domains (4) summary

pfam09457
Location:1068 → 1108

RBD-FIP; FIP domain

pfam10174
Location:155 → 982

Cast; RIM-binding protein of the cytomatrix active zone

pfam10211
Location:767 → 832

Ax_dynein_light; Axonemal dynein light chain

cl21478
Location:918 → 989

ATP-synt_B; ATP synthase B/B' CF(0)
XM_017019070.2 → XP_016874559.1 ELKS/Rab6-interacting/CAST family member 1 isoform X14
XM_017019065.2 → XP_016874554.1 ELKS/Rab6-interacting/CAST family member 1 isoform X9
XM_017019066.2 → XP_016874555.1 ELKS/Rab6-interacting/CAST family member 1 isoform X11

Related

ENSP00000410064.2, ENST00000440394.7
XM_047428571.1 → XP_047284527.1 ELKS/Rab6-interacting/CAST family member 1 isoform X10
XM_017019067.2 → XP_016874556.1 ELKS/Rab6-interacting/CAST family member 1 isoform X12

UniProtKB/Swiss-Prot

Q8IUD2

Conserved Domains (4) summary

pfam09457
Location:1040 → 1080

RBD-FIP; FIP domain

pfam10174
Location:155 → 954

Cast; RIM-binding protein of the cytomatrix active zone

pfam10211
Location:739 → 804

Ax_dynein_light; Axonemal dynein light chain

cl21478
Location:890 → 961

ATP-synt_B; ATP synthase B/B' CF(0)
XM_047428578.1 → XP_047284534.1 ELKS/Rab6-interacting/CAST family member 1 isoform X15
XM_017019072.2 → XP_016874561.1 ELKS/Rab6-interacting/CAST family member 1 isoform X16
XM_047428580.1 → XP_047284536.1 ELKS/Rab6-interacting/CAST family member 1 isoform X17
XM_047428583.1 → XP_047284539.1 ELKS/Rab6-interacting/CAST family member 1 isoform X20
XM_047428581.1 → XP_047284537.1 ELKS/Rab6-interacting/CAST family member 1 isoform X18
XM_047428584.1 → XP_047284540.1 ELKS/Rab6-interacting/CAST family member 1 isoform X21

UniProtKB/TrEMBL

X6RM00

Related

ENSP00000445336.2, ENST00000542302.6
XM_047428582.1 → XP_047284538.1 ELKS/Rab6-interacting/CAST family member 1 isoform X19
XM_017019056.2 → XP_016874545.1 ELKS/Rab6-interacting/CAST family member 1 isoform X1
XM_047428559.1 → XP_047284515.1 ELKS/Rab6-interacting/CAST family member 1 isoform X3
XM_047428564.1 → XP_047284520.1 ELKS/Rab6-interacting/CAST family member 1 isoform X7
XM_047428556.1 → XP_047284512.1 ELKS/Rab6-interacting/CAST family member 1 isoform X2
XM_047428560.1 → XP_047284516.1 ELKS/Rab6-interacting/CAST family member 1 isoform X4
XM_047428567.1 → XP_047284523.1 ELKS/Rab6-interacting/CAST family member 1 isoform X8

UniProtKB/Swiss-Prot

A2RU77, A7E295, D3DUP7, D3DUP8, Q6NVK2, Q8IUD2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1

Related

ENSP00000468263.1, ENST00000589028.6
XM_047428577.1 → XP_047284533.1 ELKS/Rab6-interacting/CAST family member 1 isoform X14
XM_047428569.1 → XP_047284525.1 ELKS/Rab6-interacting/CAST family member 1 isoform X9
XM_047428573.1 → XP_047284529.1 ELKS/Rab6-interacting/CAST family member 1 isoform X10
XM_047428575.1 → XP_047284531.1 ELKS/Rab6-interacting/CAST family member 1 isoform X12
XM_017019074.2 → XP_016874563.1 ELKS/Rab6-interacting/CAST family member 1 isoform X22

RNA

XR_001748631.3 RNA Sequence

Reference GRCh38.p14 PATCHES

Genomic

NW_013171809.1 Reference GRCh38.p14 PATCHES

Range

38589..100408

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

NC_060936.1 Alternate T2T-CHM13v2.0

Range

985850..1490194

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054371509.1 → XP_054227484.1 ELKS/Rab6-interacting/CAST family member 1 isoform X8

UniProtKB/Swiss-Prot

A2RU77, A7E295, D3DUP7, D3DUP8, Q6NVK2, Q8IUD2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1
XM_054371501.1 → XP_054227476.1 ELKS/Rab6-interacting/CAST family member 1 isoform X4
XM_054371492.1 → XP_054227467.1 ELKS/Rab6-interacting/CAST family member 1 isoform X1
XM_054371507.1 → XP_054227482.1 ELKS/Rab6-interacting/CAST family member 1 isoform X7
XM_054371496.1 → XP_054227471.1 ELKS/Rab6-interacting/CAST family member 1 isoform X2
XM_054371514.1 → XP_054227489.1 ELKS/Rab6-interacting/CAST family member 1 isoform X9
XM_054371520.1 → XP_054227495.1 ELKS/Rab6-interacting/CAST family member 1 isoform X12
XM_054371491.1 → XP_054227466.1 ELKS/Rab6-interacting/CAST family member 1 isoform X1
XM_054371502.1 → XP_054227477.1 ELKS/Rab6-interacting/CAST family member 1 isoform X5
XM_054371521.1 → XP_054227496.1 ELKS/Rab6-interacting/CAST family member 1 isoform X13
XM_054371504.1 → XP_054227479.1 ELKS/Rab6-interacting/CAST family member 1 isoform X7
XM_054371495.1 → XP_054227470.1 ELKS/Rab6-interacting/CAST family member 1 isoform X2
XM_054371503.1 → XP_054227478.1 ELKS/Rab6-interacting/CAST family member 1 isoform X6

UniProtKB/TrEMBL

X6RLX0
XM_054371500.1 → XP_054227475.1 ELKS/Rab6-interacting/CAST family member 1 isoform X4
XM_054371508.1 → XP_054227483.1 ELKS/Rab6-interacting/CAST family member 1 isoform X8

UniProtKB/Swiss-Prot

A2RU77, A7E295, D3DUP7, D3DUP8, Q6NVK2, Q8IUD2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1
XM_054371511.1 → XP_054227486.1 ELKS/Rab6-interacting/CAST family member 1 isoform X9
XM_054371516.1 → XP_054227491.1 ELKS/Rab6-interacting/CAST family member 1 isoform X10
XM_054371518.1 → XP_054227493.1 ELKS/Rab6-interacting/CAST family member 1 isoform X12
XM_054371527.1 → XP_054227502.1 ELKS/Rab6-interacting/CAST family member 1 isoform X15
XM_054371528.1 → XP_054227503.1 ELKS/Rab6-interacting/CAST family member 1 isoform X16
XM_054371529.1 → XP_054227504.1 ELKS/Rab6-interacting/CAST family member 1 isoform X17
XM_054371533.1 → XP_054227508.1 ELKS/Rab6-interacting/CAST family member 1 isoform X20
XM_054371530.1 → XP_054227505.1 ELKS/Rab6-interacting/CAST family member 1 isoform X18
XM_054371534.1 → XP_054227509.1 ELKS/Rab6-interacting/CAST family member 1 isoform X21

UniProtKB/TrEMBL

X6RM00
XM_054371532.1 → XP_054227507.1 ELKS/Rab6-interacting/CAST family member 1 isoform X24
XM_054371535.1 → XP_054227510.1 ELKS/Rab6-interacting/CAST family member 1 isoform X25
XM_054371489.1 → XP_054227464.1 ELKS/Rab6-interacting/CAST family member 1 isoform X1
XM_054371505.1 → XP_054227480.1 ELKS/Rab6-interacting/CAST family member 1 isoform X7
XM_054371493.1 → XP_054227468.1 ELKS/Rab6-interacting/CAST family member 1 isoform X2
XM_054371499.1 → XP_054227474.1 ELKS/Rab6-interacting/CAST family member 1 isoform X4
XM_054371510.1 → XP_054227485.1 ELKS/Rab6-interacting/CAST family member 1 isoform X8

UniProtKB/Swiss-Prot

A2RU77, A7E295, D3DUP7, D3DUP8, Q6NVK2, Q8IUD2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1
XM_054371523.1 → XP_054227498.1 ELKS/Rab6-interacting/CAST family member 1 isoform X14
XM_054371512.1 → XP_054227487.1 ELKS/Rab6-interacting/CAST family member 1 isoform X9
XM_054371515.1 → XP_054227490.1 ELKS/Rab6-interacting/CAST family member 1 isoform X10
XM_054371519.1 → XP_054227494.1 ELKS/Rab6-interacting/CAST family member 1 isoform X12
XM_054371525.1 → XP_054227500.1 ELKS/Rab6-interacting/CAST family member 1 isoform X15
XM_054371490.1 → XP_054227465.1 ELKS/Rab6-interacting/CAST family member 1 isoform X1
XM_054371497.1 → XP_054227472.1 ELKS/Rab6-interacting/CAST family member 1 isoform X3
XM_054371506.1 → XP_054227481.1 ELKS/Rab6-interacting/CAST family member 1 isoform X7
XM_054371522.1 → XP_054227497.1 ELKS/Rab6-interacting/CAST family member 1 isoform X23
XM_054371494.1 → XP_054227469.1 ELKS/Rab6-interacting/CAST family member 1 isoform X2
XM_054371498.1 → XP_054227473.1 ELKS/Rab6-interacting/CAST family member 1 isoform X4
XM_054371524.1 → XP_054227499.1 ELKS/Rab6-interacting/CAST family member 1 isoform X14
XM_054371513.1 → XP_054227488.1 ELKS/Rab6-interacting/CAST family member 1 isoform X9
XM_054371517.1 → XP_054227492.1 ELKS/Rab6-interacting/CAST family member 1 isoform X10
XM_054371526.1 → XP_054227501.1 ELKS/Rab6-interacting/CAST family member 1 isoform X15
XM_054371531.1 → XP_054227506.1 ELKS/Rab6-interacting/CAST family member 1 isoform X19
XM_054371536.1 → XP_054227511.1 ELKS/Rab6-interacting/CAST family member 1 isoform X22