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    Gr59c Gustatory receptor 59c [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 192481, updated on 17-Dec-2024

    Summary

    Official Symbol
    Gr59cprovided by FlyBase
    Official Full Name
    Gustatory receptor 59cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0041235
    Locus tag
    Dmel_CG30186
    See related
    AllianceGenome:FB:FBgn0041235
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    59D.2; 59D2; CG13543; CG30186; Dmel\CG30186; GR59c; GR59D.2; Gr59D2
    Summary
    Enables ionotropic bitter taste receptor activity and ionotropic sweet taste receptor activity. Involved in sensory perception of bitter taste and sensory perception of sweet taste. Predicted to be located in membrane. Predicted to be active in several cellular components, including axon; dendrite; and neuronal cell body. Is expressed in adult labellum sensillum; gustatory receptor neurons; and larval gnathal ganglion. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Gr59c in Genome Data Viewer
    Location:
    59C4-59C4; 2-102 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23102477..23103733, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18990000..18991256, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L37-2 Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 59d Neighboring gene long non-coding RNA:CR44781

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ionotropic bitter taste receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables ionotropic sweet taste receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables ligand-gated monoatomic ion channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables sweet taste receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables taste receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables taste receptor activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in monoatomic ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in sensory perception of bitter taste IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in sensory perception of bitter taste IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sensory perception of sweet taste IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sensory perception of taste IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sensory perception of taste ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in sensory perception of taste NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    gustatory receptor 59c
    Names
    CG30186-PA
    Gr59c-PA
    gustatory receptor 59D.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23102477..23103733 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166586.1NP_726292.1  gustatory receptor 59c [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726292.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9W1U5
      Related
      FBpp0071887, FBtr0071977
      Conserved Domains (1) summary
      pfam08395
      Location:9394
      7tm_7; 7tm Chemosensory receptor